Publications

2022

A brief morning rest period benefits cardiac repair in pressure overload hypertrophy and postmyocardial infarction.
Reitz CJ, Rasouli M, Alibhai FJ, Khatua TN, Pyle WG, Martino TA. A brief morning rest period benefits cardiac repair in pressure overload hypertrophy and postmyocardial infarction. JCI Insight. 2022 Nov 22;7(22):e164700. doi: 10.1172/jci.insight.164700. PMID: 36256456; PMCID: PMC9746813.
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The Impact of Sex, Circadian Disruption, and the ClockΔ19/Δ19 Genotype on Alcohol Drinking in Mice.
Rizk AA, Jenkins BW, Al-Sabagh Y, Hamidullah S, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. The Impact of Sex, Circadian Disruption, and the ClockΔ19/Δ19 Genotype on Alcohol Drinking in Mice. Genes (Basel). 2022 Apr 15;13(4):701. doi: 10.3390/genes13040701. PMID: 35456507; PMCID: PMC9031797.
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Rev-erb α Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice
Al-Sabagh Y, Thorpe HHA, Jenkins BW, Hamidullah S, Talhat MA, Suggett CB, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. Rev-erbα Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice. Int J Mol Sci. 2022 May 6;23(9):5197. doi: 10.3390/ijms23095197. PMID: 35563586; PMCID: PMC9104180.
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Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension – 2021 NHLBI Workshop Report.
Gumz ML, Shimbo D, Abdalla M, Balijepalli RC, Benedict C, Chen Y, Earnest DJ, Gamble KL, Garrison SR, Gong MC, Hogenesch JB, Hong Y, Ivy JR, Joe B, Laposky AD, Liang M, MacLaughlin EJ, Martino TA, Pollock DM, Redline S, Rogers A, Dan Rudic R, Schernhammer ES, Stergiou GS, St-Onge MP, Wang X, Wright J, Oh YS. Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension – 2021 NHLBI Workshop Report. Hypertension. 2023 Mar;80(3):503-522. doi: 10.1161/HYPERTENSIONAHA.122.19372. Epub 2022
Nov 30. PMID: 36448463; PMCID: PMC9931676.
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2021

Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress.
Inna Rabinovich-Nikitin, Mina Rasouli, Cristine J Reitz, Illana Posen, Victoria Margulets, Rimpy Dhingra, Tarak N Khatua, James A Thliveris, Tami A Martino , Lorrie A Kirshenbaum. Autophagy. 2021 Nov;17(11):3794-3812. PMID: 34085589
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Circadian influence on inflammatory response during cardiovascular disease.
Iman S Aziz, Adam M McMahon, David Friedman, Inna Rabinovich-Nikitin, Lorrie A Kirshenbaum, Tami A Martino. Curr Opin Pharmacol. 2021 Apr;57:60-70. PMID: 33340915
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Blood flow restriction training and the high-performance athlete: science to application.
Christopher Pignanelli, Danny Christiansen, Jamie F Burr. J Appl Physiol (1985). 2021 Apr 1;130(4):1163-1170. PMID: 33600282.
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Cannabis and Athletic Performance.
Jamie F Burr, Christian P Cheung, Andreas M Kasper, Scott H Gillham, Graeme L Close. Sports Med. 2021 Sep;51(Suppl 1):75-87. PMID: 34515970.
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Editorial: Blood Flow Restriction: Rehabilitation to Performance.
Stephen D Patterson, Jamie F Burr, Stuart Warmington. Front Physiol. 2021 Apr 30;12:566421. PMID: 33995115.
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Sink or swim: innovations in aquatic health.
Lee Hill, Margo Mountjoy, James Miller, Jamie Burr. J Sports Med Phys Fitness. 2021 Aug;61(8):1104-1114. PMID: 34137575.
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Ischemic Preconditioning: Modulating Pain Sensitivity and Exercise Performance.
Joshua T Slysz, Jamie F Burr. Front Physiol. 2021 Jun 22;12:696488. PMID: 34239452.
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Vascular Function Is Differentially Altered by Distance after Prolonged Running.
Trevor J King, Alexandra M Coates, Joshua C Tremblay, Joshua T Slysz, Heather L Petrick, Christopher Pignanelli, Philip J Millar, Jamie F Burr. Med Sci Sports Exerc. 2021 Mar 1;53(3):597-605. PMID: 32804900.
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Cardiac autonomic recovery following traditional and augmented remote ischemic preconditioning.
William N Morley, Alexandra M Coates, Jamie F Burr. Eur J Appl Physiol. 2021 Jan;121(1):265-277. PMID: 33047259.
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Blood Flow Restriction Combined with Electrical Stimulation Attenuates Thigh Muscle Disuse Atrophy.
Joshua T Slysz, Matthew Boston, Robert King, Christopher Pignanelli, Geoffrey A Power, Jamie F Burr. Med Sci Sports Exerc. 2021 May 1;53(5):1033-1040. PMID: 33105390.
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Exercise alters cardiac function independent of acute systemic inflammation in healthy men.
Alexandra M Coates, Heather L Petrick, Philip J Millar, Jamie F Burr. Am J Physiol Heart Circ Physiol. 2021 May 1;320(5):H1762-H1773. PMID: 33710926.
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Examining the relationship between arterial stiffness and swim-training volume in elite aquatic athletes.
Christian P Cheung, Alexandra M Coates, Katharine D Currie, Trevor J King, Margo L Mountjoy, Jamie F Burr. Eur J Appl Physiol. 2021 Sep;121(9):2635-2645. PMID: 34132871.
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Examining the Relationship between Exercise Dependence, Disordered Eating, and Low Energy Availability.
Megan A Kuikman, Margo Mountjoy, Jamie F Burr. Nutrients. 2021 Jul 28;13(8):2601. PMID: 34444761.
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Moderate Load Resisted Sprints Do Not Improve Subsequent Sprint Performance in Varsity-Level Sprinters.
Kyle M A Thompson, Alanna K Whinton, Shane Ferth, Lawrence L Spriet, Jamie F Burr. J Strength Cond Res. 2021 Jan 1;35(1):72-77. PMID: 29570579.
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Endurance and Sprint Training Improve Glycemia and V?O2peak but only Frequent Endurance Benefits Blood Pressure and Lipidemia.
Heather L Petrick, Trevor J King, Christopher Pignanelli, Tara E Vanderlinde, Jeremy N Cohen, Graham P Holloway, Jamie F Burr. Med Sci Sports Exerc. 2021 Jun 1;53(6):1194-1205. PMID: 33315809.
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Habitual cannabis use is associated with altered cardiac mechanics and arterial stiffness, but not endothelial function in young healthy smokers.
Christian P Cheung, Alexandra M Coates, Philip J Millar, Jamie F Burr. J Appl Physiol (1985). 2021 Mar 1;130(3):660-670. PMID: 33444123.
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Blood flow restriction in the presence or absence of muscle contractions does not preserve vasculature structure and function following 14-days of limb immobilization.
Jeremy N Cohen, Joshua T Slysz, Trevor J King, Alexandra M Coates, Robert T King, Jamie F Burr. Eur J Appl Physiol. 2021 Sep;121(9):2437-2447. PMID: 34002326.
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The Dendrite Arbor of Purkinje Cells Is Altered Following to Tail Regeneration in the Leopard Gecko.
Stefanie S Bradley, Erika Howe, Craig D C Bailey, Matthew K Vickaryous. Integr Comp Biol. 2021 Sep 8;61(2):370-384. PMID: 34038505.
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Cranial ornamentation in the Late Cretaceous nodosaurid ankylosaur Hungarosaurus.
Attila Osi, Janos Magyar, Karoly Rosta, Matthew Vickaryous. PeerJ. 2021 Mar 3;9:e11010. PMID: 33717709.
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Lizard osteoderms – Morphological characterisation, biomimetic design and manufacturing based on three species.
Ce Liang, Arsalan Marghoub, Loic Kever, Sergio Bertazzo, Arkhat Abzhanov, Matthew Vickaryous, Anthony Herrel, Susan E Evans, Mehran Moazen. Bioinspir Biomim. 2021 Oct 25;16(6). PMID: 34525458.
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Future Tail Tales: A Forward-Looking, Integrative Perspective on Tail Research.
M J Schwaner, S T Hsieh, I Braasch, S Bradley, C B Campos, C E Collins, C M Donatelli, F E Fish, O E Fitch, B E Flammang, B E Jackson, A Jusufi, P J Mekdara, A Patel, B J Swalla, M Vickaryous, C P McGowan. Integr Comp Biol. 2021 Sep 8;61(2):521-537. PMID: 33999184.
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Cutaneous tactile sensitivity before and after tail loss and regeneration in the leopard gecko ( Eublepharis macularius)
Stefanie S Bradley, Erika Howe, Leah R Bent, Matthew K Vickaryous. J Exp Biol. 2021 Mar 1;224(Pt 5):jeb234054. PMID: 33526555.
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Characteristics and outcomes of cats with and without pacemaker placement for high-grade atrioventricular block.
M E Colpitts, S Fonfara, G Monteith, A R Pires, A Wong, S Raheb, M Lynne O’Sullivan. J Vet Cardiol. 2021 Apr;34:37-47. PMID: 33548737.
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ShcA expression in podocytes is dispensable for glomerular development but its upregulation is associated with kidney disease.
Claire E Martin, Nina Jones. Am J Transl Res. 2021 Aug 15;13(8):9874-9882. PMID: 34540124.
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Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma Multiforme.
Manali Tilak, Jennifer Holborn, Laura A New, Jasmin Lalonde, Nina Jones. Int J Mol Sci. 2021 Feb 12;22(4):1831. PMID: 33673213.
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Lower sympathetic transduction of blood pressure in uncontrolled hypertensives: physiological adaptation, methodological limitation, or both?
Massimo Nardone, Philip J Millar. J Hum Hypertens. 2021 Nov 18. PMID: 34795392.
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Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow.
Massimo Nardone, Carlin Katerberg, Anthony V Incognito, Andre L Teixeira, Lauro C Vianna, Philip J Millar. Am J Physiol Heart Circ Physiol. 2021 Oct 1;321(4):H798-H806. PMID: 34506224.
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Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise.
Jordan B Lee, Karambir Notay, Jeremy D Seed, Massimo Nardone, Lucas J Omazic, Philip J Millar. Med Sci Sports Exerc. 2021 Dec 1;53(12):2596-2604. PMID: 34310499.
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Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?
Massimo Nardone, Anthony V Incognito, Muhammad M Kathia, Lucas J Omazic, Jordan B Lee, Andre L Teixeira, Shengkun Xie, Lauro C Vianna, Philip J Millar. Am J Physiol Regul Integr Comp Physiol. 2021 Sep 1;321(3):R484-R494. PMID: 34287075.
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Postprandial superior mesenteric artery blood flow is related to changes in peripheral pulse wave harmonics and heart rate: implications for wearable technology?
Eamon Abdullah, Jordan B Lee, Karambir Notay, Philip J Millar. J Appl Physiol (1985). 2021 Aug 1;131(2):681-688. PMID: 34264128.
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Muscle sympathetic single-unit responses during rhythmic handgrip exercise and isocapnic hypoxia in males: the role of sympathoexcitation magnitude.
Anthony V Incognito, Andre L Teixeira, Brooke M Shafer, Massimo Nardone, Tyler D Vermeulen, Glen E Foster, Philip J Millar. Neurophysiol. 2021 Jul 1;126(1):170-180. PMID: 34133241.
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Blood Pressure Responses to Static and Dynamic Knee Extensor Exercise between Sexes: Role of Absolute Contraction Intensity.
Jordan B Lee, William Lutz, Lucas J Omazic, Mitchell A Jordan, Joseph Cacoilo, Matthew Garland, Geoffrey A Power, Philip J Millar. Med Sci Sports Exerc. 2021 Sep 1;53(9):1958-1968. PMID: 33756524.
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Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury.
Jordan W Squair, Matthieu Gautier, Lois Mahe, Jan Elaine Soriano, Andreas Rowald, Arnaud Bichat, Newton Cho, Mark A Anderson, Nicholas D James, Jerome Gandar, Anthony V Incognito, Giuseppe Schiavone, Zoe K Sarafis, Achilleas Laskaratos, Kay Bartholdi, Robin Demesmaeker, Salif Komi, Charlotte Moerman, Bita Vaseghi, Berkeley Scott, Ryan Rosentreter, Claudia Kathe, Jimmy Ravier, Laura McCracken, Xiaoyang Kang, Nicolas Vachicouras, Florian Fallegger, Ileana Jelescu, YunLong Cheng, Qin Li, Rik Buschman, Nicolas Buse, Tim Denison, Sean Dukelow, Rebecca Charbonneau, Ian Rigby, Steven K Boyd, Philip J Millar, Eduardo Martin Moraud, Marco Capogrosso, Fabien B Wagner, Quentin Barraud, Erwan Bezard, Stephanie P Lacour, Jocelyne Bloch, Gregoire Courtine, Aaron A Phillips. Nature. 2021 Feb;590(7845):308-314. PMID: 33505019.
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Remote ischemic conditioning for acute respiratory distress syndrome in COVID-19.
Anthony V Incognito, Philip J Millar, W Glen Pyle. Am J Physiol Lung Cell Mol Physiol. 2021 Mar 1;320(3):L331-L338. PMID: 33404365.
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Do skeletal muscle motor units and microvascular units align to help match blood flow to metabolic demand?
Coral L Murrant, Nicole M Fletcher, Eamon J H Fitzpatrick, Kinley S Gee. Eur J Appl Physiol. 2021 May;121(5):1241-1254. PMID: 33538852.
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Capillaries communicate with the arteriolar microvascular network by a pannexin/purinergic-dependent pathway in hamster skeletal muscle.
Iain R Lamb, Nicole M Novielli-Kuntz, Coral L Murrant. Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1699-H1711. PMID: 33606585.
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Cold acclimation induces life stage-specific responses in the cardiac proteome of western painted turtles (Chrysemys picta bellii): implications for anoxia tolerance.
Sarah L Alderman, Claire L Riggs, Oliver M N Bullingham, Todd E Gillis, Daniel E Warren. J Exp Biol. 2021 Jul 15;224(14):jeb242387. PMID: 34328184.
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Pharmacokinetics and bioavailability of ketoprofen when compounded with iron dextran for use in nursing piglets.
Kristen J Reynolds, Ron Johnson, Robert M Friendship, Jennifer Brown, Saad Enouri, Ronette Gehring, Terri L O’Sullivan. Can Vet J. 2021 Nov;62(11):1211-1218. PMID: 34728849.
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Pharmacokinetics and pharmacodynamics of doxycycline in a Streptococcusequi subsp. zooepidemicus infection model in horses.
Ronan J J Chapuis, Joe S Smith, Fabienne D Uehlinger, Melissa Meachem, Ron Johnson, Patricia M Dowling. J Vet Pharmacol Ther. 2021 Sep;44(5):766-775. PMID: 34057219.
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Feline hypertrophic cardiomyopathy: reduced microvascular density and involvement of CD34+ interstitial cells.
Josep M Monne Rodriguez, Sonja Fonfara, Udo Hetzel, Anja Kipar. Vet Pathol. 2021 Dec 27:3009858211062631. PMID: 34955067.
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Association of myocardial parasitic load with cardiac biomarkers and other selected variables in 10 dogs with advanced Canine Leishmaniasis.
Domingo Casamian-Sorrosal, Rafael Barrera-Chacon, Sonja Fonfara, Silvia Belinchon-Lorenzo, Luis Gomez-Gordo, Javier Galapero-Arroyo, Javier Fernandez-Cotrina, Jose Ignacio Cristobal-Verdejo, Francisco Javier Duque. Vet Rec. 2021 Sep;189(6):e198. PMID: 33899945.
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Myocardial transcription of inflammatory and remodeling markers in cats with hypertrophic cardiomyopathy and systemic diseases associated with an inflammatory phenotype.
Sonja Fonfara, Sarah Kitz, Gabrielle Monteith, Shelley Hahn, Anja Kipar. Res Vet Sci. 2021 May;136:484-494. PMID: 33848803.
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2020

Circadian Mutant Mice with Obesity and Metabolic Syndrome are Resilient to Cardiovascular Disease.
Cristine J Reitz, Faisal J Alibhai , Bruna Gazzi de Lima Seolin, Ashley Susan Nemec-Bakk, Neelam Khaper, Tami A Martino. Am J Physiol Heart Circ Physiol. 2020 Sep 28. PMID: 32986958
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Circadian influence on the microbiome improves heart failure outcomes.
Priya Mistry, Cristine J Reitz, Tarak Nath Khatua, Mina Rasouli, Kaitlyn Oliphant, Martin E Young, Emma Allen-Vercoe, Tami A Martino. J Mol Cell Cardiol. 2020 Sep 19;149:54-72. PMID: 32961201
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Differential effects of REV-ERBa/b agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption.
Sobuj Mia, Mariame S Kane , Mary N Latimer , Cristine J Reitz , Ravi Sonkar, Gloria A Benavides, Samuel R Smith, Stuart J Frank , Tami A Martino , Jianhua Zhang , Victor M Darley-Usmar , Martin E Young. Am J Physiol Heart Circ Physiol. 2020 Jun 1PMID: 32357113
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The Time for Circadian Medicine.
Tami A Martino, Mary E Harrington. J Biol Rhythms. 2020 Oct;35(5):419-420. PMID: 32746705
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Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study.
Adrian Boswood, Sonya G Gordon, Jens Haggstrom, Martin Vanselow, Gerhard Wess, Rebecca L Stepien, Mark A Oyama, Bruce W Keene, John Bonagura, Kristin A MacDonald, Mark Patteson , Sarah Smith , Philip R Fox, Karen Sanderson, Richard Woolley , Viktor Szatmari , Pierre Menaut , Whitney M Church , M Lynne OSullivan , Jean-Philippe Jaudon , Jan-Gerd Kresken, John Rush , Kirstie A Barrett , Steven L Rosenthal , Ashley B Saunders , Ingrid Ljungvall , Michael Deinert, Eric Bomassi, Amara H Estrada, Maria J Fernandez Del Palacio, N Sydney Moise , Jonathan A Abbott, Yoko Fujii, Alan Spier , Michael W Luethy , Roberto A Santilli , Masami Uechi, Anna Tidholm , Christoph Schummer, Philip Watson J Vet Intern Med. 2020 May PMID: 32200574
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Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases.
Kendal Prill, John F Dawson. Int J Mol Sci. 2020 Jan 15;21(2):542. PMID: 31952119
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The Dark Side of Actin: Cardiac actin variants highlight the role of allostery in disease development.
Grace Zi Teng, John F Dawson. Arch Biochem Biophys. 2020 Oct 10;695:108624.PMID: 33049292
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An examination of individual responses to ischemic preconditioning and the effect of repeated ischemic preconditioning on cycling performance.
J T Slysz, H L Petrick, J P Marrow, J F Burr. Eur J Sport Sci. 2020 Jun;20(5):633-640. PMID: 31429381
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Low-load resistance training to task failure with and without blood flow restriction: muscular functional and structural adaptations.
Christopher Pignanelli, Heather L Petrick, Fatemeh Keyvani, George J F Heigenhauser, Joe Quadrilatero, Graham P Holloway, Jamie F Burr. Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R284-R295. PMID: 31823670
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Impairment of Thermoregulation and Performance via Mild Dehydration in Ice Hockey Goaltenders.
CDevin G McCarthy, Kate A Wickham, Tyler F Vermeulen, Danielle L Nyman, Shane Ferth, Jamie M Pereira, Dennis J Larson, Jamie F Burr, Lawrence L Spriet. Int J Sports Physiol Perform. 2020 Feb 25;15(6):833-840. PMID: 32101792
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In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle.
Heather L Petrick, Henver S Brunetta, Chris Pignanelli, Everson A Nunes, Luc J C van Loon, Jamie F Burr, Graham P Holloway. J Physiol. 2020 Jul 31. doi: 10.1113/JP280032. PMID: 32735362
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Vascular Function Is Differentially Altered by Distance following Prolonged Running.
Trevor J King, Alexandra M Coates, Joshua C Tremblay, Joshua T Slysz, Heather L Petrick, Christopher Pignanelli, Philip J Millar, Jamie F Burr. Med Sci Sports Exerc. 2020 Aug 15. PMID: 32804900
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Repeated Application of a Novel Creatine Cream Improves Muscular Peak and Average Power in Male Subjects.
Alanna K Whinton, Katelynn Donahoe, Ruirui Gao, Kyle M A Thompson, Rachel Aubry, Travis J Saunders, Adam Johnston, Philip D Chilibeck, Jamie F Burr. J Strength Cond Res. 2020 Sep;34(9):2482-2491. PMID: 32865944
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In Response to: Risk of Muscle Damage With Blood Flow-Restricted Exercise Should Not Be Overlooked.
Kyle M A Thompson, Jamie F Burr. Clin J Sport Med. 2020 Sep 15. PMID: 32941382
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The Effect of a Stretch-Shortening Cycle on Muscle Activation and Muscle Oxygen Consumption: A Study of History-Dependenc.
Kevin E Caron, Jamie F Burr, Geoffrey A Power. J Strength Cond Res. 2020 Sep 16. PMID: 32947570
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Cardiac autonomic recovery following traditional and augmented remote ischemic preconditioning.
William N Morley, Alexandra M Coates, Jamie F Burr. Eur J Appl Physiol. 2020 Oct 13.
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Alterations in Cardiac Function Following Endurance Exercise Are Not Duration Dependent.
Alexandra M Coates, Trevor J King, Katharine D Currie, Joshua C Tremblay, Heather L Petrick, Joshua T Slysz, Christopher Pignanelli, Jordan A Berard, Philip J Millar, Jamie F Burr. Front Physiol. 2020 Sep 18 PMID: 33071833.
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Blood Flow Restriction Combined with Electrical Stimulation Attenuates Thigh Muscle Disuse Atrophy.
Joshua T Slysz, Matthew Boston, Robert King, Christopher Pignanelli, Geoffrey A Power, Jamie F Burr. Med Sci Sports Exerc. 2020 Oct 22.
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Off-Ice Resisted Sprints Best Predict All-Out Skating Performance in Varsity Hockey Players.
Kyle M A Thompson, Abdul Safadie, Josh Ford, Jamie F Burr. J Strength Cond Res. 2020 Oct 30.
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Response: Commentary: Can Blood Flow Restricted Exercise Cause Muscle Damage? Commentary on Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety.
Jamie F Burr, Luke Hughes, Stuart Warmington, Brendan R Scott, Johnny Owens, Takashi Abe, Jakob L Nielsen, Cleiton Augusto Libardi, Gilberto Laurentino, Gabriel Rodrigues Neto, Christopher Brandner, Juan Martin-Hernandez, Jeremy Loenneke, Stephen D Patterson. Front Physiol. 2020 Oct 30;11:574633.
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Multivalent nephrin-Nck interactions define a threshold for clustering and tyrosine-dependent nephrin endocytosis.
Claire E Martin, Laura A New, Noah J Phippen, Ava Keyvani Chahi, Alexander E Mitro, Tomoko Takano, Tony Pawson, Ivan M Blasutig, Nina Jones. J Cell Sci. 2020 Feb 24 PMID: 31974115.
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Sympathetic neural modulation of arterial stiffness in humans.
Massimo Nardone, John S Floras, Philip J Millar. Am J Physiol Heart Circ Physiol. 2020 Oct 9 PMID: 33035441.
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Sympathetic arterial baroreflex hysteresis in humans: different patterns during low- and high-pressure levels.
Anthony V Incognito , Milena Samora, Andrew D Shepherd, Roberta A Cartafina , Gabriel M N Guimaraes , Mauricio Daher , Lauro C Vianna , Philip J Millar. Am J Physiol Heart Circ Physiol. 2020 Oct 1 PMID: 32857604.
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Influence of Sex and Age on Muscle Sympathetic Nerve Activity of Healthy Normotensive Adults.
Daniel A Keir, Mark B Badrov, George Tomlinson, Catherine F Notarius, Derek S Kimmerly, Philip J Millar, J Kevin Shoemaker, John S Floras Hypertension. 2020 Sep. PMID: 32783757.
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Case Studies in Physiology: Sympathetic neural discharge patterns in a healthy young male during end-expiratory breath hold-induced sinus pause.
Tyler D Vermeulen, Brooke M Shafer, Anthony V Incognito, Massimo Nardone, Andre L Teixeira, Philip J Millar, J Kevin Shoemaker, Glen E Foster. J Appl Physiol (1985). 2020 Aug 1. PMID: 32644911.
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Within-breath sympathetic baroreflex sensitivity is modulated by lung volume but unaffected by acute intermittent hypercapnic hypoxia in men.
Massimo Nardone, Andre L Teixeira, Anthony V Incognito, Tyler D Vermeulen, Brooke M Shafer, Philip J Millar, Glen E Foster. Am J Physiol Heart Circ Physiol. 2020 Jul 1. PMID: 32502372.
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Looking beyond the mean: Are racial differences in beat-to-beat blood pressure variability among young men a harbinger for future cardiovascular risk?
Philip J Millar. Exp Physiol. 2020 Jul PMID: 32428314.
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New insights into the complexity of arterial baroreflex control of muscle sympathetic outflow in humans.
Anthony V Incognito, Philip J Millar. J Physiol 2020 May PMID: 32246770.
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Muscle sympathetic single-unit response patterns during progressive muscle metaboreflex activation in young healthy adults.
Anthony V Incognito, Massimo Nardone, Andr� L Teixeira, Jordan B Lee, Muhammad M Kathia, Philip J Millar J Neurophysiol . 2020 Sep 1;124(3):682-690. PMID: 32727266.
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2019

SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome.
Cristine J Reitz , Faisal J Alibhai , Tarak N Khatua , Mina Rasouli , Byram W Bridle , Thomas P Burris, Tami A Martino, Commun Biol. 2019 Oct 3;2:353. PMID: 31602405
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Circadian-Regulated Cell Death in Cardiovascular Diseases.
Inna Rabinovich-Nikitin , Brooke Lieberman , Tami A Martino , Lorrie A Kirshenbaum, Circulation. 2019 Feb 12;139(7):965-980.PMID: 30742538
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The Clock Mechanism Influences Neurobiology and Adaptations to Heart Failure in Clock 19/19 Mice With Implications for Circadian Medicine.
Austin T H Duong , Cristine J Reitz , Emma L Louth , Samantha D Creighton, Mina Rasouli , Ashley Zwaiman , Jeffrey T Kroetsch , Steffen-Sebastian Bolz , Boyer D Winters , Craig D C Bailey , Tami A Martino, Sci Rep. 2019 Mar 21;9(1):4994. PMID: 30899044
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A crosslinked and ribosylated actin trimer does not interact productively with myosin.
Navneet Sidhu, John F Dawson. Biochem Cell Biol. 2019 Apr;97(2):140-147. PMID: 30193076
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M-class hypertrophic cardiomyopathy cardiac actin mutations increase calcium sensitivity of regulated thin filaments.
Grace Zi Teng, Zeeshan Shaikh, Haidun Liu, John F Dawson. Biochem Biophys Res Commun. 2019 Oct 29;519(1):148-152. PMID: 31481237
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Impact of 8 weeks of repeated ischemic preconditioning on running performance.
Joshua T Slysz, Jamie F Burr. Eur J Appl Physiol. 2019 Jun;119(6):1431-1437. PMID: 30953176
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Ischemic Preconditioning: Improved Cycling Performance Despite Nocebo Expectation.
Christian P Cheung, Joshua T Slysz, Jamie F Burr. Int J Sports Physiol Perform. 2019 Oct 11;1-7. PMID: 31188700
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Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H 2 O 2 emission rates in human skeletal muscle.
Heather L Petrick, Christopher Pignanelli, Pierre-Andre Barbeau, Tyler A Churchward-Venne, Kaitlyn M J H Dennis, Luc J C van Loon, Jamie F Burr, Gijs H Goossens, Graham P Holloway. J Physiol. 2019 Aug;597(15):3985-3997. PMID: 31194254
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Effects of dynamic arm and leg exercise on muscle sympathetic nerve activity and vascular conductance in the inactive leg.
Connor J Doherty, Trevor J King, Anthony V Incognito, Jordan B Lee, Andrew D Shepherd, Joseph A Cacoilo, Joshua T Slysz, Jamie F Burr, Philip J Millar. J Appl Physiol (1985). 2019 Aug 1;127(2):464-472. PMID: 31246555
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The relationship of high-intensity cross-training with arterial stiffness.
Jamie F Burr, Jenny L Beck, John J Duroche. J Sport Health Sci. 2019 Jul;8(4):370-375. PMID: 31333891
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Localization of phosphotyrosine adaptor protein ShcD/SHC4 in the adult rat central nervous system.
Hannah N Robeson, Hayley R Lau, Laura A New , Jasmin Lalonde, John N Armstrong, Nina Jones. BMC Neurosci. 2019 Dec 10 PMID: 31823725
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2018

Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology.
Khaper N, Bailey CDC, Ghugre NR, Reitz C, Awosanmi Z, Waines R, Martino TA. Free Radic Biol Med. 2018:1;119:85-92. PMID: 29146117
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Constitutive cardiomyocyte proliferation in the leopard gecko (Eublepharis macularius).
Jacyniak K, Vickaryous MK. J Morphol. 2018 Sep;279(9):1355-1367.PMID: 30221788
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PI3Ka-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.
Patel VB, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, McLean BA, Basu R, Zhang P, Shah S, Dawson JF, Pyle WG, Hazra M, Kassiri Z, Hazra S, Vanhaesebroeck B, McCulloch CA, Oudit GY. Nat Commun. 2018;9(1):5390. PMID: 30568254
– Print Publication

Analytical validation of cardiac troponin I assays in horses.
Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW. J Vet Diagn Invest. 2018;(2):226-232. PMID: 29224512
– Print Publication

A crosslinked and ribosylated actin trimer does not interact productively with myosin.
Sidhu N, Dawson JF. Biochem Cell Biol. 2018. PMID: 30193076
– Print Publication

Identification of the actc1c cardiac actin gene in zebrafish.
Ojehomon M, Alderman SL, Sandhu L, Sutcliffe S, Van Raay T, Gillis TE, Dawson JF. Prog Biophys Mol Biol. 2018;138:32-37. PMID: 29913180
– Print Publication

Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy.
Despond EA, Dawson JF. Front Physiol. 2018;9:405. PMID: 29719515
– Print Publication

How the expression of green fluorescent protein and human cardiac actin in the heart influences cardiac function and aerobic performance in zebrafish Danio rerio.
Avey SR, Ojehomon M, Dawson JF, Gillis TE. J Fish Biol. 2018;92(1):177-189. PMID: 29194605
– Print Publication

Cardiac actin changes in the actomyosin interface have different effects on myosin duty ratio.
Liu H, Henein M, Anillo M, Dawson JF. Biochem Cell Biol. 2018;96(1):26-31. PMID: 28972856
– Print Publication

Characterization of a novel disease-associated mutation within NPHS1 and its effects on nephrin phosphorylation and signaling.
Cooper CJ, Dutta NT, Martin CE, Piscione TD, Thorner PS, Jones N. PLoS One. 2018;13(9):e0203905. PMID: 30212551
– Print Publication

Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation.
Smith TL, Van Slyke P, Jones N, Dumont DJ, McGlade CJ. Cell Signal. 2018 Nov;51:211-221. PMID: 30077653
– Print Publication

Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond.
Martin CE, Jones N. Front Endocrinol (Lausanne). 2018;9:302. PMID: 29922234
– Print Publication

Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors.
Kostas M, Haugsten EM, Zhen Y, Sorensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J. Mol Cell Proteomics. 2018;17(5):850-870. PMID: 29371290
– Print Publication

ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.
Martin CE, Petersen KA, Aoudjit L, Tilak M, Eremina V, Hardy WR, Quaggin SE, Takano T, Jones N. J Am Soc Nephrol. 2018;29(1):92-103. PMID: 29018139
– Print Publication

Left Ventricular Structure and Function in Elite Swimmers and Runners.
Currie KD, Coates AM, Slysz JT, Aubry RL, Whinton AK, Mountjoy ML, Millar PJ, Burr JF. Front Physiol. 2018;9:1700. PMID: 30546320
– Print Publication

Evidence for differential control of muscle sympathetic single units during mild sympathoexcitation in young healthy humans.
Incognito AV, Doherty CJ, Nardone M, Lee JB, Notay K, Seed JD, Millar PJ. Am J Physiol Heart Circ Physiol. 2018. PMID: 30388036
– Print Publication

Cardiovascular responses during isometric exercise following lengthening and shortening contractions.
Seed JD, St Peters B, Power GA, Millar PJ. J Appl Physiol (1985). 2018. PMID: 30382808
– Print Publication

TRPV1 and BDKRB2 receptor polymorphisms can influence the exercise pressor reflex.
Notay K, Klingel SL, Lee JB, Doherty CJ, Seed JD, Swiatczak M, Mutch DM, Millar PJ. J Physiol. 2018;596(21):5135-5148. PMID: 30206938
– Print Publication

Pharmacological assessment of the arterial baroreflex in a young healthy obese male with extremely low baseline muscle sympathetic nerve activity.
Incognito AV, Samora M, Cartafina RA, Guimaraes GMN, Daher M, Millar PJ, Vianna LC. Clin Auton Res. 2018;28(6):593-595. PMID: 30128682
– Print Publication

Blunted Cardiac Output from Overtraining Is Related to Increased Arterial Stiffness.
Coates AM, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018;50(12):2459-2464. PMID: 30102678
– Print Publication

Microneurographic characterization of sympathetic responses during 1-leg exercise in young and middle-aged humans.
Notarius CF, Millar PJ, Doherty CJ, Incognito AV, Haruki N, O’Donnell E, Floras JS. Appl Physiol Nutr Metab. 2018. PMID: 30063163
– Print Publication

Hypertensive Response With Exercise to Reveal Increased Cardiovascular Risk in Adults With Aortic Coarctation Repair: Value and Caution.
Millar PJ, Oechslin EN. Can J Cardiol. 2018;34(5):536-539. PMID: 29731016
– Print Publication

Heart Rate Variability Responses of Individuals With and Without Saline-Induced Obstructive Sleep Apnea.
Vena D, Bradley TD, Millar PJ, Floras JS, Rubianto J, Gavrilovic B, Perger E, Yadollahi A. J Clin Sleep Med. 2018;14(4):503-510. PMID: 29609720
– Print Publication

Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms.
Allwood MA, Edgett BA, Eadie AL, Huber JS, Romanova N, Millar PJ, Brunt KR, Simpson JA. J Physiol. 2018;596(15):3391-3410. PMID: 29604069
– Print Publication

Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.
Munoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H. J Hypertens. 2018;36(7):1477-1485. PMID: 29557905
– Print Publication

Comparison of laboratory and ambulatory measures of central blood pressure and pulse wave reflection: hitting the target or missing the mark?.
Burns MJ, Seed JD, Incognito AV, Doherty CJ, Notay K, Millar PJ. J Am Soc Hypertens. 2018;12(4):275-284. PMID: 29477564
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Evidence for Pressure-Independent Sympathetic Modulation of Central Pulse Wave Velocity.
Nardone M, Incognito AV, Millar PJ. J Am Heart Assoc. 2018;7(3). PMID: 29378730
– Print Publication

A comparison of static and dynamic cerebral autoregulation during mild whole-body cold stress in individuals with and without cervical spinal cord injury: a pilot study.
van der Scheer JW, Kamijo YI, Leicht CA, Millar PJ, Shibasaki M, Goosey-Tolfrey VL, Tajima F. Spinal Cord. 2018;56(5):469-477. PMID: 29330514
– Print Publication

Three Weeks of Overload Training Increases Resting Muscle Sympathetic Activity.
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018;50(5):928-937. PMID: 29206785
– Print Publication

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women.
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ. Med Sci Sports Exerc. 2018;50(4):778-784. PMID: 29135658
– Print Publication

Interindividual variability in muscle sympathetic responses to static handgrip in young men: evidence for sympathetic responder types?.
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Am J Physiol Regul Integr Comp Physiol. 2018;314(1):R114-R121. PMID: 29070505
– Print Publication

Muscle sympathetic nerve responses to passive and active one-legged cycling: insights into the contributions of central command.
Doherty CJ, Incognito AV, Notay K, Burns MJ, Slysz JT, Seed JD, Nardone M, Burr JF, Millar PJ. Am J Physiol Heart Circ Physiol. 2018;314(1):H3-H10. PMID: 28939650
– Print Publication

Enhanced Metabolic Stress Augments Ischemic Preconditioning for Exercise Performance.
Slysz JT, Burr JF. Front Physiol. 2018;9:1621. PMID: 30498458
– Print Publication

The Acute Metabolic and Vascular Impact of Interrupting Prolonged Sitting: A Systematic Review and Meta-Analysis.
Saunders TJ, Atkinson HF, Burr J, MacEwen B, Skeaff CM, Peddie MC. Sports Med. 2018;48(10):2347-2366. PMID: 30078066
– Print Publication

Testing a novel isokinetic dynamometer constructed using a 1080 Quantum.
Whinton AK, Thompson KMA, Power GA, Burr JF. PLoS One. 2018;13(7):e0201179. PMID: 30028864
– Print Publication

An Assessment of Running Power as a Training Metric for Elite and Recreational Runners.
Aubry RL, Power GA, Burr JF. J Strength Cond Res. 2018;32(8):2258-2264. PMID: 29912073
– Print Publication

Prevalence of Indicators of Low Energy Availability in Elite Female Sprinters.
Sygo J, Coates AM, Sesbreno E, Mountjoy ML, Burr JF. Int J Sport Nutr Exerc Metab. 2018;28(5):490-496. PMID: 29757049
– Print Publication

Investigating the use of pre-training measures of autonomic regulation for assessing functional overreaching in endurance athletes.
Coates AM, Hammond S, Burr JF. Eur J Sport Sci. 2018;18(7):965-974. PMID: 29635969
– Print Publication

Moderate Load Resisted Sprints do Not Improve Subsequent Sprint Performance in Varsity Level Sprinters.
Thompson KMA, Whinton AK, Ferth S, Spriet LL, Burr JF. J Strength Cond Res. 2018. PMID: 29570579
– Print Publication

Ischemic Preconditioning: No Influence on Maximal Sprint Acceleration Performance.
Thompson KMA, Whinton AK, Ferth S, Spriet LL, Burr JF. Int J Sports Physiol Perform. 2018;13(8):986-990. PMID: 29345532
– Print Publication

Risks of Exertional Rhabdomyolysis With Blood Flow-Restricted Training: Beyond the Case Report.
Thompson KMA, Slysz JT, Burr JF. Clin J Sport Med. 2018;28(6):491-492. PMID: 29084035
– Print Publication

The Effects of Blood Flow Restricted Electrostimulation on Strength and Hypertrophy.
Slysz JT, Burr JF. J Sport Rehabil. 2018;27(3):257-262. PMID: 28513326
– Print Publication

Clinicopathological features and comorbidities of cats with mild, moderate or severe hyperthyroidism: a radioiodine referral population.
Watson N, Murray JK, Fonfara S, Hibbert A. J Feline Med Surg. 2018 Dec;20(12):1130-1137. PMID: 29432704
– Print Publication

Splenic blood-flow response following myocardial infarction in rat.
Ruggiero SA, Huber JS, Murrant CL, Brunt KR, Simpson JA. Can J Physiol Pharmacol. 2018;96(11):1060-1068. PMID: 30102865
– Print Publication

Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct.
Platt MJ, Huber JS, Romanova N, Brunt KR, Simpson JA. Front Physiol. 2018;9:472. PMID: 29867532
– Print Publication

A Comparison and Calibration of a Wrist-Worn Blood Pressure Monitor for Patient Management: Assessing the Reliability of Innovative Blood Pressure Devices.
Melville S, Teskey R, Philip S, Simpson JA, Lutchmedial S, Brunt KR. J Med Internet Res. 2018;20(4):e111. PMID: 29695375
– Print Publication

Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats.
Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP. Am J Physiol Regul Integr Comp Physiol. 2018;315(2):R191-R204. PMID: 29513565
– Print Publication

Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain.
Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou YQ, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT. Am J Physiol Regul Integr Comp Physiol. 2018;314(4):R611-R622. PMID: 29351418
– Print Publication

Heritable Skeletal Disorders Arising from Defects in Processing and Transport of Type I Procollagen from the ER: Perspectives on Possible Therapeutic Approaches.
Cutrona MB, Morgan NE, Simpson JC. Handb Exp Pharmacol. 2018;245:191-225. PMID: 29071510
– Print Publication

Transforming growth factor-B1 induces differentiation of rainbow trout (Oncorhynchus mykiss) cardiac fibroblasts into myofibroblasts.
Johnston EF, Gillis TE. J Exp Biol. 2018;221(Pt 24). PMID: 30397172
– Print Publication

Developmental and latent effects of diluted bitumen exposure on early life stages of sockeye salmon (Oncorhynchus nerka).
Alderman SL, Lin F, Gillis TE, Farrell AP, Kennedy CJ. Aquat Toxicol. 2018 Sep;202:6-15. PMID: 29966910
– Print Publication

Cellular mechanisms of slime gland refilling in Pacific hagfish (Eptatretus stoutii).
Schorno S, Gillis TE, Fudge DS. J Exp Biol. 2018;221(Pt 16). PMID: 29941614
– Print Publication

Emptying and refilling of slime glands in Atlantic (Myxine glutinosa) and Pacific (Eptatretus stoutii) hagfishes.
Schorno S, Gillis TE, Fudge DS. J Exp Biol. 2018;221(Pt 7). PMID: 29487153
– Print Publication

Arteriolar and capillary responses to CO2 and H+ in hamster skeletal muscle microvasculature: Implications for active hyperemia.
Charter ME, Lamb IR, Murrant CL. Microcirculation. 2018;25(7):e12494. PMID: 30030943
– Print Publication

Capillary response to skeletal muscle contraction: evidence that redundancy between vasodilators is physiologically relevant during active hyperaemia.
Lamb IR, Novielli NM, Murrant CL. J Physiol. 2018;596(8):1357-1372. PMID: 29417589
– Print Publication

Marginal ancestral contributions to atrial fibrillation in the Standardbred racehorse: Comparison of cases and controls.
Kraus M, Physick-Sheard P, Brito LF, Sargolzaei M, Schenkel FS. PLoS One. 2018;13(5):e0197137. PMID: 29763439
– Print Publication

2017

Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Alibhai FJ, LaMarre J, Reitz CJ, Tsimakouridze EV, Kroetsch JT, Bolz SS, Shulman A, Steinberg S, Burris TP, Oudit GY, Martino TA. J Mol Cell Cardiol. 2017;105:24-37. PMID: 28223222
– Print Publication

Female Clockd19/d19 Mice are Protected from the Development of Age-Dependent Cardiomyopathy.
Alibhai FJ, Reitz CJ, Peppler WT, Basu P, Sheppard P, Choleris E, Bakovic M, Martino TA. Cardiovasc Res. 2017 Sep 12. [Epub ahead of print]. PMID: 28927226
– Print Publication

Guidelines for Genome-Scale Analysis of Biological Rhythms.
Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, et al. Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptacek LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB. J Biol Rhythms. 2017;32(5):380-393. PMID: 29098954
– Print Publication

Cardiac Clocks and Preclinical Translation.
Mistry P, Duong A, Kirshenbaum L, Martino TA. Heart Fail Clin. 2017;13(4):657-672. Review. PMID: 28865775
– Print Publication

Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology.
Khaper N, Bailey CDC, Ghugre NR, Reitz C, Awosanmi Z, Waines R, Martino TA. Free Radic Biol Med. 2017. pii: S0891-5849(17)31199-1. [Epub ahead of print] Review. PMID: 29146117
– Print Publication

Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart.
Feridooni HA, MacDonald JK, Ghimire A, Pyle WG, Howlett SE. Am J Physiol Heart Circ Physiol. 2017;312(1):H46-H59. PMID: 27793852
– Print Publication

Analytical validation of cardiac troponin I assays in horses.
Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW. J Vet Diagn Invest. 2017 Dec 1:1040638717747070. [Epub ahead of print] PMID: 29224512
– Print Publication

Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015).
Bascunan A, Thieman Mankin KM, Saunders AB, Bright JM, Scharf V, Singh A, O’Sullivan L, Brisson B, Estrada AH, Tou SP, Ruoff C. J Vet Cardiol. 2017;19(1):35-43. PMID: 27919727
– Print Publication

Development of a technique for determination of pulmonary artery pulse wave velocity in horses.
Silva GTA, Guest BB, Gomez DE, McGregor M, Viel L, O’Sullivan ML, Runciman J, Arroyo LG. J Appl Physiol (1985). 2017;122(5):1088-1094. PMID: 28183822
– Print Publication

Assessment of platelet function in healthy cats in response to commonly prescribed antiplatelet drugs using three point-of-care platelet function tests.
Ho KK, Abrams-Ogg AC, Wood RD, O’Sullivan ML, Kirby GM, Blois SL. J Feline Med Surg. 2017;19(6):638-647. PMID: 27170631
– Print Publication

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.
Boswood A, Gordon SG, Haggstrom J, Wess G, Stepien RL, Oyama MA, Keene BW, Bonagura J, MacDonald KA, Patteson M, Smith S, Fox PR, Sanderson K, Woolley R, Szatm�ri V, Menaut P, Church WM, O’Sullivan ML, Jaudon JP, Kresken JG, Rush J, Barrett KA, Rosenthal SL, Saunders AB, Ljungvall I, Deinert M, Bomassi E, Estrada AH, Fernandez Del Palacio MJ, Moise NS, Abbott JA, Fujii Y, Spier A, Luethy MW, Santilli RA, Uechi M, Tidholm A, Schummer C, Watson P. J Vet Intern Med. 2017 Dec 6. [Epub ahead of print] PMID: 29214723
– Print Publication

Cardiac actin changes in the actomyosin interface have different effects on myosin duty ratio.
Liu H, Henein ME, Anillo M, Dawson JF. Biochem Cell Biol. 2017 Oct 3. [Epub ahead of print] PMID: 28972856
– Print Publication

How the expression of green fluorescent protein and human cardiac actin in the heart influences cardiac function and aerobic performance in zebrafish Danio rerio.
Avey SR, Ojehomon M, Dawson JF, Gillis TE. J Fish Biol. 2017 Nov 30. [Epub ahead of print] PMID: 29194605

Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Wills MK, Keyvani Chahi A, Lau HR, Tilak M, Guild BD, New LA, Lu P, Jacquet K, Meakin SO, Bisson N, Jones N. J Biol Chem. 2017;292(14):5748-5759. PMID: 28213521
– Print Publication

The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking.
Wills MKB, Lau HR, Jones N. J Cell Sci. 2017;130(17):2808-2820. PMID: 28724758
– Print Publication

ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.
Martin CE, Petersen KA, Aoudjit L, Tilak M, Eremina V, Hardy WR, Quaggin SE, Takano T, Jones N. J Am Soc Nephrol. 2017 Oct 10. pii: ASN.2017030285. [Epub ahead of print] PMID: 29018139
– Print Publication

Ischemic preconditioning does not alter muscle sympathetic responses to static handgrip and metaboreflex activation in young healthy men.
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Physiol Rep. 2017;5(14). pii: e13342. PMID: 28720715
– Print Publication

Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study.
Notay K, Incognito AV, Millar PJ. Am J Physiol Heart Circ Physiol. 2017;313(1):H59-H65. PMID: 28476923
– Print Publication

Muscle sympathetic nerve responses to passive and active one-legged cycling: Insight into the contributions of central command.
Doherty CJ, Incognito AV, Notay K, Burns MJ, Slysz JT, Seed JD, Nardone M, Burr JF, Millar PJ. Am J Physiol Heart Circ Physiol. 2017 Sep 22:ajpheart.00494.2017. [Epub ahead of print] PMID: 28939650
– Print Publication

Inter-individual variability in muscle sympathetic responses to static handgrip in young men: Evidence for sympathetic responder types?
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Am J Physiol Regul Integr Comp Physiol. 2017 Oct 25:ajpregu.00266.2017. [Epub ahead of print] PMID: 29070505
– Print Publication

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women.
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ. Med Sci Sports Exerc. 2017 Nov 10. [Epub ahead of print] PMID: 29135658
– Print Publication

Sex Differences in Cardiac Baroreflex Sensitivity following Isometric Handgrip Exercise.
Teixeira AL, Ritti-Dias R, Antonino D, Bottaro M, Millar PJ, Vianna LC. Med Sci Sports Exerc. 2017 Nov 13. [Epub ahead of print] PMID: 29135601
– Print Publication

Three Weeks of Overload Training Increases Resting Muscle Sympathetic Activity.
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF. Med Sci Sports Exerc. 2017 Dec 2. [Epub ahead of print] PMID: 29206785
– Print Publication

The Effects of Blood Flow Restricted Electrostimulation on Strength & Hypertrophy.
Slysz J, Burr JF. J Sport Rehabil. 2017:1-17. [Epub ahead of print] PMID: 28513326
-Print Publication

Incidence of Iron Deficiency and Iron Deficient Anemia in Elite Runners and Triathletes.
Coates A, Mountjoy M, Burr J. Clin J Sport Med. 2017;27(5):493-498. PMID: 27606953
– Print Publication

Risks of Exertional Rhabdomyolysis With Blood Flow-Restricted Training: Beyond the Case Report.
Thompson KMA, Slysz JT, Burr JF. Clin J Sport Med. 2017 Oct 26. [Epub ahead of print] PMID: 29084035
– Print Publication

UPEI-400, a conjugate of lipoic acid and scopoletin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Connell BJ, Saleh MC, Rajagopal D, Saleh TM. Food Chem Toxicol. 2017;100:175-182. PMID: 28017701
– Print Publication

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents.
Afifi TH, Okasha RM, Ahmed HEA, Ilas J, Saleh T, Abd-El-Aziz AS. EXCLI J. 2017;16:868-902. PMID: 28828001
– Print Publication

A novel synthetic chemical entity (UPEI-800) is neuroprotective in vitro and in an in vivo rat model of oxidative stress.
Saleh TM, Saleh MC, Connell BJ, Kucukkaya I, Abd-El-Aziz AS. Clin Exp Pharmacol Physiol. 2017;44(10):993-1000. PMID: 28504843
– Print Publication

A co-drug conjugate of naringenin and lipoic acid mediates neuroprotection in a rat model of oxidative stress.
Saleh TM, Saleh MC, Connell BJ, Song YH. Clin Exp Pharmacol Physiol. 2017;44(10):1008-1016. PMID: 28636787
– Print Publication

Myocardial leptin transcription in feline hypertrophic cardiomyopathy.
Fonfara S, Kitz S, Hetzel U, Kipar A. Res Vet Sci. 2017;112:105-108. PMID: 28213270
– Print Publication

Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.
Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA. Sci Transl Med. 2017;9(390). pii: eaag1303. PMID: 28515334
– Print Publication

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.
Yin JC, Platt MJ, Tian X, Wu X, Backx PH, Simpson JA, Araki T, Neel BG. Nat Commun. 2017;8:15518. PMID: 28548091
– Print Publication

Pulmonary Flow as an Improved Method for Determining Cardiac Output in Mice after Myocardial Infarction.
Platt MJ, Huber JS, Brunt KR, Simpson JA. J Am Soc Echocardiogr. 2017;30(6):612-623.e1. PMID: 28528655
– Print Publication

The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and Beta-cell mass.
Paglialunga S, Simnett G, Robson H, Hoang M, Pillai R, Arkell AM, Simpson JA, Bonen A, Huising M, Joseph JW, Holloway GP. Appl Physiol Nutr Metab. 2017;42(6):647-655. PMID: 28177704
– Print Publication

The Effect of Anthocyanin-Rich Purple Vegetable Diets on Metabolic Syndrome in Obese Zucker Rats.
Ayoub HM, McDonald MR, Sullivan JA, Tsao R, Platt M, Simpson J, Meckling KA. J Med Food. 2017;20(12):1240-1249. PMID: 28956702
– Print Publication

Temperature-induced cardiac remodelling in fish.
Keen AN, Klaiman JM, Shiels HA, Gillis TE. J Exp Biol. 2017;220(Pt 2):147-160. Review. PMID: 27852752
– Print Publication

Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance.
Alderman SL, Lin F, Farrell AP, Kennedy CJ, Gillis TE. Environ Toxicol Chem. 2017;36(2):354-360. PMID: 27328800
– Print Publication

Data for iTRAQ-based quantification of the cardiac proteome of rainbow trout (Oncorhynchus mykiss) at rest and with exercise training.
Dindia LA, Alderman SL, Gillis TE. Data Brief. 2017;13:32-36. PMID: 28560280
– Print Publication

Novel insights into cardiac remodelling revealed by proteomic analysis of the trout heart during exercise training.
Dindia LA, Alderman SL, Gillis TE. J Proteomics. 2017;161:38-46. PMID: 28365405
– Print Publication

Proteomic analysis of sockeye salmon serum as a tool for biomarker discovery and new insight into the sublethal toxicity of diluted bitumen.
Alderman SL, Dindia LA, Kennedy CJ, Farrell AP, Gillis TE. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:157-166. PMID: 28433920
– Print Publication

Transforming growth factor beta-1 (TGF-beta1) stimulates collagen synthesis in cultured rainbow trout cardiac fibroblasts.
Johnston EF, Gillis TE. J Exp Biol. 2017;220(Pt 14):2645-2653. PMID: 28495868
– Print Publication

Canadian Society for Exercise Physiology Symposium on Integrative Physiology Honouring Dr. Bengt Saltin: The use of Exercise to Study Integrative Physiology.
Murrant CL, MacDonald MJ. Appl Physiol Nutr Metab. 2017;42(1):99. PMID: 28055244
– Print Publication

Dose-dependent inhibition of uterine contractility by nitric oxide: A potential mechanism underlying persistent breeding-induced endometritis in the mare.
Khan FA, Chenier TS, Murrant CL, Foster RA, Hewson J, Scholtz EL. Theriogenology. 2017;90:59-64. PMID: 28166989
– Print Publication

Capillary endothelial cells as coordinators of skeletal muscle blood flow during active hyperemia.
Murrant CL, Lamb IR, Novielli NM. Microcirculation. 2017;24(3). Review. PMID: 28036147
– Print Publication

Associations of acute stress and overnight heart rate with feed efficiency in beef heifers.
Munro JC, Schenkel FS, Physick-Sheard PW, Fontoura AB, Miller SP, Tennessen T, Montanholi YR. Animal. 2017;11(3):452-460. PMID: 27514832
– Print Publication

Estimates of heritability of atrial fibrillation in the Standardbred racehorse.
Kraus M, Physick-Sheard PW, Brito LF, Schenkel FS. Equine Vet J. 2017;49(6):718-722. PMID: 28391631
– Print Publication

Perioperative analgesic use by Ontario veterinarians, 2012.
Reimann J, Dewey C, Bateman SW, Kerr C, Johnson R. Can Vet J. 2017;58(2):149-156. PMID: 28216684
– Print Publication

Pharmacokinetics of liposomal encapsulated buprenorphine suspension following subcutaneous administration to cats.
Johnson RJ, Kerr CL, Enouri SS, Modi P, Lascelles BDX, Del Castillo JRE. J Vet Pharmacol Ther. 2017;40(3):256-269. PMID: 27647259
– Print Publication

The Analysis of Phenylbutazone and Its Active Metabolite, Oxyphenbutazone, in Equine Tissues (Muscle, Kidney, and Liver), Urine, and Serum by LC-MS/MS.
Boison JO, Dowling P, Matus JL, Kinar J, Johnson R. J AOAC Int. 2017;100(4):1110-1122. PMID: 28145218
– Print Publication

2016

Day-Night Dependence of Gene Expression and Inflammatory Responses in the Remodeling Murine Heart post-Myocardial Infarction.
Bennardo M, Alibhai FJ, Tsimakouridze EV, Chinnappareddy N, Podobed P, Reitz CJ, Pyle WG, Simpson JA, Martino TA. Am J Physiol Regul Integr Comp Physiol. 2016:ajpregu.00200.2016. PMID: 27733386
– Print Publication

The neglected messengers: Control of cardiac myofilaments by protein phosphatases.
Lorenzen-Schmidt I, Clarke SB, Pyle WG. J Mol Cell Cardiol. 2016;101:81-89. PMID: 27721025
– Print Publication

Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015).
Bascunan A, Thieman Mankin KM, Saunders AB, Bright JM, Scharf V, Singh A, O’Sullivan L, Brisson B, Estrada AH, Tou SP, Ruoff C. J Vet Cardiol. 2016. pii: S1760-2734(16)30116-3. PMID: 27919727
– Print Publication

Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP.
Keyvani Chahi A, Martin CE, Jones N. J Biol Chem. 2016;291(24):12799-808. PMID: 27033705
– Print Publication

Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.
New LA, Martin CE, Scott RP, Platt MJ, Keyvani Chahi A, Stringer CD, Lu P, Samborska B, Eremina V, Takano T, Simpson JA, Quaggin SE, Jones N. J Am Soc Nephrol. 2016;27(8):2422-35. PMID: 26802179
– Print Publication

Cutaneous Mechanoreceptor Feedback from the Hand and Foot Can Modulate Muscle Sympathetic Nerve Activity.
Strzalkowski ND, Incognito AV, Bent LR, Millar PJ. Front Neurosci. 2016;10:568. eCollection 2016. PMID: 28008306
– Print Publication

Validity and reliability of measuring resting muscle sympathetic nerve activity using short sampling durations in healthy humans.
Notay K, Seed JD, Incognito AV, Doherty CJ, Nardone M, Burns MJ, Millar PJ. J Appl Physiol (1985). 2016;121(5):1065-1073. PMID: 27687563
– Print Publication

The Effects of Ischemic Preconditioning on Human Exercise Performance.
Incognito AV, Burr JF, Millar PJ. Sports Med. 2016;46(4):531-44. Review. PMID: 26645697
– Print Publication

Non-invasive electrocardiographic assessments of cardiac autonomic modulation in individuals with spinal cord injury.
Sharif H, Millar PJ, Incognito AV, Ditor DS. Spinal Cord. 2016;54(3):166-71. PMID: 26597693
– Print Publication

Incidence of Iron Deficiency and Iron Deficient Anemia in Elite Runners and Triathletes
Coates A, Mountjoy M, Burr J. Clin J Sport Med. 2016. PMID: 27606953
– Print Publication

The Acute Risks of Exercise in Apparently Healthy Adults and Relevance for Prevention of Cardiovascular Events.
Goodman JM, Burr JF, Banks L, Thomas SG. Can J Cardiol. 2016;32(4):523-32. Review. PMID: 27017149
– Print Publication

The efficacy of blood flow restricted exercise: A systematic review & meta-analysis.
Slysz J, Stultz J, Burr JF. Sci Med Sport. 2016;19(8):669-75. Review. PMID: 26463594
– Print Publication

UPEI-400, a conjugate of lipoic acid and scopoletin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Connell BJ, Saleh MC, Rajagopal D, Saleh TM. Food Chem Toxicol. 2016;100:175-182.[Epub ahead of print]. PMID: 28017701
– Print Publication

Usefulness of serum cardiac troponin I concentration as a marker of survival of harbor seal (Phoca vitulina) pups during rehabilitation.
Fonfara S, Sundermeyer J, Casamian Sorrosal D, Weber C, Rosenberger T. J Am Vet Med Assoc. 2016;249(12):1428-1435. PMID: 27901450
– Print Publication

“Fibroblast” pharmacotherapy – Advancing the next generation of therapeutics for clinical cardiology.
Eadie AL, Simpson JA, Brunt KR. J Mol Cell Cardiol. 2016;94:176-9. PMID: 27060557
– Print Publication

Dissecting the role of the myofilament in diaphragm dysfunction during the development of heart failure in mice.
Gillis TE, Klaiman JM, Foster A, Platt MJ, Huber JS, Corso MY, Simpson JA. Am J Physiol Heart Circ Physiol. 2016 Mar 1;310(5):H572-86. PMID: 26702144
– Print Publication

Temperature-induced cardiac remodeling in fish.
Keen AN, Klaiman JM, Shiels HA, Gillis TE. J Exp Biol. 2016. pii: jeb.128496. [Epub ahead of print] Review. PMID: 27852752
– Print Publication

A functional comparison of cardiac troponin C from representatives of three vertebrate taxa: Linking phylogeny and protein function.
Sears EJ, Gillis TE. Comp Biochem Physiol B Biochem Mol Biol. 2016;202:8-15. PMID: 27453566
– Print Publication

Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance.
Alderman SL, Lin F, Farrell AP, Kennedy CJ, Gillis TE. Environ Toxicol Chem. 2016. [Epub ahead of print]. PMID: 27328800
– Print Publication

Capillary endothelial cells as coordinators of skeletal muscle blood flow during active hyperaemia.
Murrant CL, Lamb IR, Novielli NM. Microcirculation. 2016. [Epub ahead of print]. PMID: 28036147
– Print Publication

Associations of acute stress and overnight heart rate with feed efficiency in beef heifers.
Munro JC, Schenkel FS, Physick-Sheard PW, Fontoura AB, Miller SP, Tennessen T, Montanholi YR. Animal. 2016 Aug 12:1-9. [Epub ahead of print]. PMID: 27514832
– Print Publication

Pharmacokinetics of liposomal encapsulated buprenorphine suspension following subcutaneous administration to cats.
Johnson RJ, Kerr CL, Enouri SS, Modi P, Lascelles BD, Del Castillo JR. J Vet Pharmacol Ther. 2016. [Epub ahead of print]. PMID: 27647259
– Print Publication

2015

Disruption of Circadian Rhythms and Sleep on Critical Illness and the Impact on Cardiovascular Events.
Reitz CJ, Martino TA. Curr Pharm Des. 2015;21(24):3505-11. PMID: 26144940
– Print Publication

Consequences of Circadian and Sleep Disturbances for the Cardiovascular System.
Alibhai FJ, Tsimakouridze EV, Reitz CJ, Pyle WG, Martino TA. Can J Cardiol. 2015;31(7):860-72. Epub 2015 Jan 26. PMID: 26031297
– Print Publication

Male-Specific Cardiac Dysfunction in CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)-Deficient Mice.
Basu P, Alibhai FJ, Tsimakouridze EV, Singh RK, Paglialunga S, Holloway GP, Martino TA, Bakovic M. Mol Cell Biol. 2015;35(15):2641-57. Epub 2015 May 18. PMID: 25986609
– Print Publication

Therapeutic applications of circadian rhythms for the cardiovascular system.
Tsimakouridze EV, Alibhai FJ, Martino TA. Front Pharmacol. 2015;6:77. eCollection 2015. PMID: 25941487
– Print Publication

Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology.
Martino TA, Young ME. J Biol Rhythms. 2015;30(3):183-205. Epub 2015 Mar 22. PMID: 25800587
– Print Publication

‘The Cardiac Clock’ in Circadian Clocks: Role in Health and Disease.
Alibhai FJ, Tsimakouridze EV, Reitz CJ, Pyle WG, Martino TA. Springer APS. 2015. In Press.

2-Deoxy-adenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy.
Cheng Y, Hogarth KA, O’Sullivan ML, Regnier M, Pyle WG. Am J Physiol Heart Circ Physiol. 2015:ajpheart.00530.2015. PMID: 26497964
– Print Publication

Do cardiac actin mutations lead to altered actomyosin interactions?
Dahari M, Dawson JF. Biochem Cell Biol. 2015;93(4):330-4. PMID: 26194323
– Print Publication

The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.
Bai F, Caster HM, Dawson JF, Kawai M. J Mol Cell Cardiol. 2015;79:123-32. PMID: 25451174
– Print Publication

Dissecting the role of the myofilament in diaphragm dysfunction during the development of heart failure in mice.
Gillis TE, Klaiman JM, Foster AJ, Platt MJ, Huber JS, Corso MY, Simpson JA. Am J Physiol Heart Circ Physiol. 2015:ajpheart.00773.2015. PMID: 26702144
– Print Publication

Characterizing the metabolic capacity of the anoxic hagfish heart.
Gillis TE, Regan MD, Cox GK, Harter TS, Brauner CJ, Richards JG, Farrell AP. J Exp Biol. 2015;218(Pt 23):3754-61. PMID: 26486366
– Print Publication

Exercise-mediated IL-6 signaling occurs independent of inflammation and is amplified by training in mouse adipose tissue.
Castellani L, Perry CG, Macpherson RE, Root-McCaig J, Huber JS, Arkell AM, Simpson JA, Wright DC. J Appl Physiol. 2015;119(11):1347-54. PMID: 26472868
– Print Publication

Respiratory muscle weakness in the Zucker diabetic fatty rat.
Allwood MA, Foster AJ, Arkell AM, Beaudoin MS, Snook LA, Romanova N, Murrant CL, Holloway GP, Wright DC, Simpson JA. Am J Physiol Regul Integr Comp Physiol. 2015;309(7):R780-7. PMID: 26246509
– Print Publication

High intensity interval and endurance training have opposing effects on markers of heart failure and cardiac remodeling in hypertensive rats.
Holloway TM, Bloemberg D, da Silva ML, Simpson JA, Quadrilatero J, Spriet LL. PLoS One. 2015 Mar;10(3):e0121138. eCollection 2015. PMID: 25803693
– Print Publication

Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice.
Macpherson RE, Huber JS, Frendo-Cumbo S, Simpson JA, Wright DC. Med Sci Sports Exerc. 2015;47(10):2034-42. PMID: 25785928
– Print Publication

Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFa.
Aschar-Sobbi R, Izaddoustdar F, Korogyi AS, Wang Q, Farman GP, Yang F, Yang W, Dorian D, Simpson JA, Tuomi JM, Jones DL, Nanthakumar K, Cox B, Wehrens XH, Dorian P, Backx PH. Nat Commun. 2015;6:6018. PMID: 25598495
– Print Publication

Lennie: a smartphone application with novel implications for the management of animal colonies.
Allwood MA, Griffith D, Allen C, Reed J, Mahmoud QH, Brunt KR, Simpson JA. Lab Anim. 2015;49(3):258-62. PMID: 25653169
– Print Publication

Muscle sympathetic activity in resting and exercising humans with and without heart failure.
Notarius CF, Millar PJ, Floras JS. Appl Physiol Nutr Metab. 2015;40(11):1107-15. PMID: 26481289
– Print Publication

Paradoxical muscle sympathetic reflex activation in human heart failure.
Millar PJ, Murai H, Floras JS. Circulation. 2015;131(5):459-68. PMID: 25466974
– Print Publication

Divergent muscle sympathetic responses to dynamic leg exercise in heart failure and age-matched healthy subjects.
Notarius CF, Millar PJ, Murai H, Morris BL, Marzolini S, Oh P, Floras JS. J Physiol. 2015;593(3):715-22. PMID: 25398528
– Print Publication

Association between Resting State Brain Functional Connectivity and Muscle Sympathetic Burst Incidence.
Taylor KS, Kucyi A, Millar PJ, Murai H, Kimmerly DS, Morris BL Rn, Bradley TD, Floras JS. J Neurophysiol. 2015:jn.00675.2015. PMID: 26538607
– Print Publication

The efficacy of blood flow restricted exercise: A systematic review & meta-analysis.
Slysz J, Stultz J, Burr JF. J Sci Med Sport. 2015. pii: S1440-2440(15)00182-6. PMID: 26463594
– Print Publication

Influence of Active Recovery on Cardiovascular Function During Ice Hockey.
Burr JF, Slysz JT, Boulter MS, Warburton DE. Sports Med Open. 2015;1(1):27. PMID: 26339567
– Print Publication

Arterial stiffness results from eccentrically biased downhill running exercise.
Burr JF, Boulter M, Beck K. J Sci Med Sport. 2015;18(2):230-5. PMID: 24709362
– Print Publication

A systematic review of standing and treadmill desks in the workplace.
MacEwen BT, MacDonald DJ, Burr JF. Prev Med. 2015;70:50-8. PMID: 25448843
– Print Publication

Sex differences in cardiac function after prolonged strenuous exercise.
Cote AT, Phillips AA, Foulds HJ, Charlesworth SA, Bredin SS, Burr JF, Koehle MS, Warburton DE. Clin J Sport Med. 2015;25(3):276-83. PMID: 25010150
– Print Publication

2014

Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.
Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, Gamble KL. J Biol Rhythms. 2014 Aug;29(4):257-76. doi: 10.1177/0748730414543141. PMID: 25238855
– Print Publication

Circadian regulation of myocardial sarcomeric Titin-cap (Tcap, telethonin): identification of cardiac clock-controlled genes using open access bioinformatics data.
Podobed PS, Alibhai FJ, Chow CW, Martino TA. PLoS One. 2014 Aug 14;9(8):e104907. PMID: 25121604
– Print Publication

The day/night proteome in the murine heart.
Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze EV, Ratcliffe WF, Mackay A, Simpson J, Wright DC, Kirby GM, Young ME, Martino TA. Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R121-37. PMID: 24789993
– Print Publication

Short-term disruption of diurnal rhythms after murine myocardial infarction adversely affects long-term myocardial structure and function.
Alibhai FJ, Tsimakouridze EV, Chinnappareddy N, Wright DC, Billia F, O’Sullivan ML, Pyle WG, Sole MJ, Martino TA. Circ Res. 2014 May 23;114(11):1713-22. doi: 10.1161/CIRCRESAHA.114.302995. PMID: 24687134
– Print Publication

Cardiac contraction, calcium transients, and myofilament calcium sensitivity fluctuate with the estrous cycle in young adult female mice.
MacDonald JK, Pyle WG, Reitz CJ, Howlett SE. Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H938-53. doi: 10.1152/ajpheart.00730.2013. PMID: 24464757
– Print Publication

Cold acclimation increases cardiac myofilament function and ventricular pressure generation in trout.
Klaiman JM, Pyle WG, Gillis TE. J Exp Biol. 2014 Dec 1;217(Pt 23):4132-40. doi: 10.1242/jeb.109041. PMID: 25278471
– Print Publication

Troponin assays in the assessment of the equine myocardium.
Rossi TM, Pyle WG, Maxie MG, Pearl DL, Physick-Sheard PW. Equine Vet J. 2014 May;46(3):270-5. doi: 10.1111/evj.12209. PMID: 24215569
– Print Publication

Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P.
Bai F, Caster HM, Rubenstein PA, Dawson JF, Kawai M. J Mol Cell Cardiol. 2014 Sep;74:64-75. doi: 10.1016/j.yjmcc.2014.04.014. PMID: 24793351
– Print Publication

Altered interactions between cardiac myosin binding protein-C and a-cardiac actin variants associated with cardiomyopathies.
Chow ML, Shaffer JF, Harris SP, Dawson JF. Arch Biochem Biophys. 2014 May 15;550-551:28-32. doi: 10.1016/j.abb.2014.04.003. PMID: 24736382
– Print Publication

Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Allwood MA, Kinobe RT, Ballantyne L, Romanova N, Melo LG, Ward CA, Brunt KR, Simpson JA. Cardiovasc Pathol. 2014 Jul-Aug;23(4):231-7. doi: 10.1016/j.carpath.2014.03.007. PMID: 24813593
– Print Publication

Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Beaudoin MS, Perry CG, Arkell AM, Chabowski A, Simpson JA, Wright DC, Holloway GP. J Physiol. 2014 Jun 15;592(Pt 12):2519-33. doi: 10.1113/jphysiol.2013.270538. PMID: 24639481
– Print Publication

Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats.
Beaudoin MS, Snook LA, Arkell AM, Stefanson A, Wan Z, Simpson JA, Holloway GP, Wright DC. Obesity (Silver Spring). 2014 Jul;22(7):1632-42. doi: 10.1002/oby.20717. PMID: 24500776
– Print Publication

Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine.
Murrant CL, Dodd JD, Foster AJ, Inch KA, Muckle FR, Ruiz DA, Simpson JA, Scholl JH. J Physiol. 2014 Mar 15;592(Pt 6):1267-81. doi: 10.1113/jphysiol.2013.264259. PMID: 24469074
– Print Publication

Cold acclimation alters the connective tissue content of the zebrafish (Danio rerio) heart.
Johnson AC, Turko AJ, Klaiman JM, Johnston EF, Gillis TE. J Exp Biol. 2014 Jun 1;217(Pt 11):1868-75. doi: 10.1242/jeb.101196. PMID: 24577447
– Print Publication

Self-assembly enhances the strength of fibers made from vimentin intermediate filament proteins.
Pinto N, Yang FC, Negishi A, Rheinstadter MC, Gillis TE, Fudge DS. Biomacromolecules. 2014 Feb 10;15(2):574-81. doi: 10.1021/bm401600a. PMID: 24359121
– Print Publication

Exercise as medicine: role in the management of primary hypertension.
Millar PJ, Goodman JM. Appl Physiol Nutr Metab. 2014 Jul;39(7):856-8. doi: 10.1139/apnm-2014-0006. PMID: 24773307
– Print Publication

Isometric exercise training for blood pressure management: a systematic review and meta-analysis.
Carlson DJ, Dieberg G, Hess NC, Millar PJ, Smart NA. Mayo Clin Proc. 2014 Mar;89(3):327-34. doi: 10.1016/j.mayocp.2013.10.030. PMID: 24582191
– Print Publication

Statins and the autonomic nervous system.
Millar PJ, Floras JS. Clin Sci (Lond). 2014 Mar;126(6):401-15. doi: 10.1042/CS20130332. PMID: 24274967
– Print Publication

Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions.
Millar PJ, McGowan CL, Cornelissen VA, Araujo CG, Swaine IL. Sports Med. 2014 Mar;44(3):345-56. doi: 10.1007/s40279-013-0118-x. PMID: 24174307
– Print Publication

Inverse relationship between muscle sympathetic activity during exercise and peak oxygen uptake in subjects with and without heart failure.
Notarius CF, Millar PJ, Murai H, Morris BL, Floras JS. J Am Coll Cardiol. 2014 Feb 18;63(6):605-6. doi: 10.1016/j.jacc.2013.08.693. PMID: 23994407
– Print Publication

Characterisation of baroreflex sensitivity of recreational ultra-endurance athletes.
Foulds HJ, Cote AT, Phillips AA, Charlesworth SA, Bredin SS, Burr JF, Drury CT, Ngai S, Fougere RJ, Ivey AC, Warburton DE. Eur J Sport Sci. 2014;14(7):686-94. doi: 10.1080/17461391.2014.884169. PMID: 24601942
– Print Publication

Temporal response of arterial stiffness to ultra-marathon.
Burr JF, Phillips AA, Drury TC, Ivey AC, Warburton DE. Int J Sports Med. 2014 Jul;35(8):658-63. doi: 10.1055/s-0033-1358478. PMID: 24408767
– Print Publication

Long-term ultra-marathon running and arterial compliance.
Burr JF, Drury CT, Phillips AA, Ivey A, Ku J, Warburton DE. J Sci Med Sport. 2014 May;17(3):322-5. doi: 10.1016/j.jsams.2013.04.018. PMID: 23707138
– Print Publication

Breed predisposition and heritability of atrial fibrillation in the Standardbred horse: a retrospective case-control study.
Physick-Sheard P, Kraus M, Basrur P, McGurrin K, Kenney D, Schenkel F. J Vet Cardiol. 2014 Sep;16(3):173-84. doi: 10.1016/j.jvc.2014.03.006. PMID: 25087649
– Print Publication

2013

The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart.
Fares E, Pyle WG, Ray G, Rose RA, Denovan-Wright EM, Chen RP, Howlett SE. PLoS One. 2013 Sep 18;8(9):e74719. doi: 10.1371/journal.pone.0074719. eCollection 2013. PMID: 24058623
– Print Publication

Low molecular weight fibroblast growth factor-2 signals via protein kinase C and myofibrillar proteins to protect against postischemic cardiac dysfunction.
Manning JR, Perkins SO, Sinclair EA, Gao X, Zhang Y, Newman G, Pyle WG, Schultz Jel J. Am J Physiol Heart Circ Physiol. 2013 May 15;304(10):H1382-96. doi: 10.1152/ajpheart.00613.2012. PMID: 23479264
– Print Publication

Identifying a role of the actin capping protein CapZ in B-adrenergic receptor signalling.
Gaikis L, Stewart D, Johnson R, Pyle WG. Acta Physiol (Oxf). 2013 Jan;207(1):173-82. doi: 10.1111/j.1748-1716.2012.02470.x. PMID: 22882973
– Print Publication

Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions.
Arora PD, Wang Y, Bresnick A, Dawson J, Janmey PA, McCulloch CA. Mol Biol Cell. 2013 Mar;24(6):734-47. doi: 10.1091/mbc.E12-10-0754. PMID: 23325791
– Print Publication

Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats.
Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC. Am J Physiol Regul Integr Comp Physiol. 2013 Sep;305(5):R542-51. doi: 10.1152/ajpregu.00200.2013. PMID: 23824959
– Print Publication

Chronic hypoxia exposure of trout embryos alters swimming performance and cardiac gene expression in larvae.
Johnston EF, Alderman SL, Gillis TE. Physiol Biochem Zool. 2013 Sep-Oct;86(5):567-75. doi: 10.1086/672012. PMID: 23995487
– Print Publication

Nucleus-localized 21.5-kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane-associated 18.5-kDa isoform.
Smith GS, Samborska B, Hawley SP, Klaiman JM, Gillis TE, Jones N, Boggs JM, Harauz G. J Neurosci Res. 2013 Mar;91(3):349-62. doi: 10.1002/jnr.23166. PMID: 23184356
– Print Publication

Alpha males: muscle sympathetic discharge on beat-to-beat forearm vascular conductance.
Millar PJ, O’Donnell E. J Physiol. 2013 Sep 15;591(Pt 18):4375-6. doi: 10.1113/jphysiol.2013.261743. PMID: 24037135
– Print Publication

Microneurographic evidence in healthy middle-aged humans for a sympathoexcitatory reflex activated by atrial pressure.
Millar PJ, Murai H, Morris BL, Floras JS. Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H931-8. doi: 10.1152/ajpheart.00375.2013. PMID: 23851279
– Print Publication

Heart rate recovery and heart rate variability are unchanged in patients with coronary artery disease following 12 weeks of high-intensity interval and moderate-intensity endurance exercise training.
Currie KD, Rosen LM, Millar PJ, McKelvie RS, MacDonald MJ. Appl Physiol Nutr Metab. 2013 Jun;38(6):644-50. doi: 10.1139/apnm-2012-0354. PMID: 23724882
– Print Publication

Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women.
Badrov MB, Bartol CL, DiBartolomeo MA, Millar PJ, McNevin NH, McGowan CL. Eur J Appl Physiol. 2013 Aug;113(8):2091-100. doi: 10.1007/s00421-013-2644-5. PMID: 23588257
– Print Publication

Reduced heart rate variability and baroreflex sensitivity in normotensive children with repaired coarctation of the aorta.
Millar PJ, Proudfoot NA, Dillenburg RF, Macdonald MJ. Int J Cardiol. 2013 Sep 20;168(1):587-8. doi: 10.1016/j.ijcard.2013.01.248. PMID: 23453876
– Print Publication

Cardiovascular stress reactivity tasks successfully predict the hypotensive response of isometric handgrip training in hypertensives.
Badrov MB, Horton S, Millar PJ, McGowan CL. Psychophysiology. 2013 Apr;50(4):407-14. doi: 10.1111/psyp.12031. PMID: 23418955
– Print Publication

Simvastatin reduces sympathetic outflow and augments endothelium-independent dilation in non-hyperlipidaemic primary hypertension.
McGowan CL, Murai H, Millar PJ, Notarius CF, Morris BL, Floras JS. Heart. 2013 Feb;99(4):240-6. doi: 10.1136/heartjnl-2012-302980. PMID: 23257173
– Print Publication

Physical activity series: cardiovascular risks of physical activity in apparently healthy individuals: risk evaluation for exercise clearance and prescription.
Goodman J, Thomas S, Burr JF. Can Fam Physician. 2013 Jan;59(1):46-9, e6-e10. PMID: 23341659
– Print Publication

Effects of injectable anesthetic combinations on left ventricular function and cardiac morphology in Sprague-Dawley rats.
Sabatini CF, O’Sullivan ML, Valcour JE, Sears W, Johnson RJ. J Am Assoc Lab Anim Sci. 2013 Jan;52(1):34-43. PMID: 23562031
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