Publications

2024

Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure Eckle, T., Bertazzo, J., Khatua, T. N., Fatemi Tabatabaei, S. R., Moori Bakhtiari, N., Walker, L. A., & Martino, T. A. (2024). Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure. Circulation research, 134(6), 675–694. https://doi.org/10.1161/CIRCRESAHA.123.323522. PMID: 38484024.
PMCID: PMC10947118

Translating metabolic and cardiovascular research into effective treatments: What’s next? Zierath, J. R., van der Velden, J., Javaheri, A., Rosenzweig, A., Muoio, D. M., Mulvihill, E. E., Martino, T. A., Rasheed, A., Chen, X. W., & Arany, Z. P. (2024). Translating metabolic and cardiovascular research into effective treatments: What’s next?. Cell, 187(15), 3880–3884. https://doi.org/10.1016/j.cell.2024.06.034. PMID: 38458859
DOI: 10.1016/j.tem.2024.02.011

Pioneering new frontiers in circadian medicine chronotherapies for cardiovascular health. Festus, I. D., Spilberg, J., Young, M. E., Cain, S., Khoshnevis, S., Smolensky, M. H., Zaheer, F., Descalzi, G., & Martino, T. A. (2024). Pioneering new frontiers in circadian medicine chronotherapies for cardiovascular health. Trends in endocrinology and metabolism: TEM, 35(7), 607–623. https://doi.org/10.1016/j.tem.2024.02.011. PMID: 38458859. DOI: 10.1016/j.tem.2024.02.011

Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats. McCallum, R. T., Thériault, R. K., Manduca, J. D., Russell, I. S. B., Culmer, A. M., Doost, J. S., Martino, T. A., & Perreault, M. L. (2024). Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats. Biology of sex differences, 15(1), 16. https://doi.org/10.1186/s13293-024-00589-0. PMID: 38350966. PMCID: PMC10863247. DOI: 10.1186/s13293-024-00589-0

One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike. Farag, H. I., Murphy, B. A., Templeman, J. R., Hanlon, C., Joshua, J., Koch, T. G., Niel, L., Shoveller, A. K., Bedecarrats, G. Y., Ellison, A., Wilcockson, D., & Martino, T. A. (2024). One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike. Journal of biological rhythms, 39(3), 237–269. https://doi.org/10.1177/07487304241228021. PMID: 38379166. PMCID: PMC11141112. DOI: 10.1177/07487304241228021

Correction: Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats. McCallum, R. T., Thériault, R. K., Manduca, J. D., Russell, I. S. B., Culmer, A. M., Doost, J. S., Martino, T. A., & Perreault, M. L. (2024). Correction: Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats. Biology of sex differences, 15(1), 31. https://doi.org/10.1186/s13293-024-00605-3. PMID: 38570795. PMCID: PMC10988937. DOI: 10.1186/s13293-024-00605-3.

High-intensity interval versus moderate-intensity continuous cycling training in Parkinson’s disease: a randomized trial. Kathia, M. M., Duplea, S. G., Bommarito, J. C., Hinks, A., Leake, E., Shannon, J., Pitman, J., Khangura, P. K., Coates, A. M., Slysz, J. T., Katerberg, C., McCarthy, D. G., Beedie, T., Malcolm, R., Witton, L. A., Connolly, B. S., Burr, J. F., Vallis, L. A., Power, G. A., & Millar, P. J. (2024). High-intensity interval versus moderate-intensity continuous cycling training in Parkinson’s disease: a randomized trial. Journal of applied physiology (Bethesda, Md. : 1985), 137(3), 603–615. PMID: 39008618. DOI: 10.1152/japplphysiol.00219.2024. https://doi.org/10.1152/japplphysiol.00219.2024

No effect of aerobic fitness on exercise-induced diaphragm fatigue in females. Payne, O. T., Leahy, M. G., Burr, J. F., Road, J. D., McKenzie, D. C., & Sheel, A. W. (2024). No effect of aerobic fitness on exercise-induced diaphragm fatigue in females. Journal of applied physiology (Bethesda, Md. : 1985), 137(5), 1145–1157. https://doi.org/10.1152/japplphysiol.00239.2024. PMID: 39236143. DOI: 10.1152/japplphysiol.00239.2024

Acute partial sleep deprivation attenuates blood pressure responses to cycling exercise. Bommarito, J. C., Stapleton, R. K., Murray, N. S., Burr, J. F., & Millar, P. J. (2024). Acute partial sleep deprivation attenuates blood pressure responses to cycling exercise. American journal of physiology. Heart and circulatory physiology, 327(4), H947–H955. https://doi.org/10.1152/ajpheart.00453.2024. PMID: 39178028. DOI: 10.1152/ajpheart.00453.2024

Blood Flow-Restricted Training and Time Trial Performance: A Cohort Study of World-Class Rowers. Thompson, K. M. A., Pethick, W. A., Clarke, J., Winegarden, A., Johnson, E., Coates, A. M., Stellingwerff, T., & Burr, J. F. (2024). Blood Flow-Restricted Training and Time Trial Performance: A Cohort Study of World-Class Rowers. Medicine and science in sports and exercise, 56(9), 1606–1614. https://doi.org/10.1249/MSS.0000000000003459. PMID: 38619968. DOI: 10.1249/MSS.0000000000003459

Impact of Blood Flow Restriction Exercise on Central Hemodynamics and Fluid Regulating Hormones. Thompson, K. M. A., Gamble, A. S. D., Coates, A. M., & Burr, J. F. (2024). Impact of Blood Flow Restriction Exercise on Central Hemodynamics and Fluid Regulating Hormones. Medicine and science in sports and exercise, 56(2), 362–369. https://doi.org/10.1249/MSS.0000000000003307. PMID: 37735813.
DOI: 10.1249/MSS.0000000000003307

Assessing Leg Blood Flow and Cardiac Output During Running Using Thermodilution. Leahy, M. G., Thompson, K. M. A., Skattebo, Ø., de Paz, J. A., Martin-Rincon, M., Garcia-Gonzalez, E., Galvan-Alvarez, V., Boushel, R., Hallén, J., Burr, J. F., & Calbet, J. A. L. (2024). Assessing Leg Blood Flow and Cardiac Output During Running Using Thermodilution. Scandinavian journal of medicine & science in sports, 34(8), e14705. https://doi.org/10.1111/sms.14705. PMID: 39056564. DOI: 10.1111/sms.14705

Carbohydrate Ingestion Increases Interstitial Glucose and Mitigates Neuromuscular Fatigue during Single-Leg Knee Extensions. Elghobashy, M. E., Richards, A. J., Malekzadeh, R., Patel, D., Turner, L. V., Burr, J. F., Power, G. A., Laham, R., Riddell, M. C., & Cheng, A. J. (2024). Carbohydrate Ingestion Increases Interstitial Glucose and Mitigates Neuromuscular Fatigue during Single-Leg Knee Extensions. Medicine and science in sports and exercise, 56(8), 1495–1504. https://doi.org/10.1249/MSS.0000000000003440. PMID: 38595179.
DOI: 10.1249/MSS.0000000000003440

The addition of blood flow restriction during resistance exercise does not increase prolonged low-frequency force depression. Pignanelli, C., Robertson, A. A., Hirsch, S. M., Power, G. A., & Burr, J. F. (2024). The addition of blood flow restriction during resistance exercise does not increase prolonged low-frequency force depression. Experimental physiology, 109(5), 738–753. https://doi.org/10.1113/EP091753. PMID: 38562023. PMCID: PMC11061635. DOI: 10.1113/EP091753

Cannabis containing THC impairs 20-min cycling time trial performance irrespective of the method of inhalation. Cheung, C. P., Baker, R. E., Coates, A. M., & Burr, J. F. (2024). Cannabis containing THC impairs 20-min cycling time trial performance irrespective of the method of inhalation. Journal of applied physiology (Bethesda, Md. : 1985), 136(3), 583–591. https://doi.org/10.1152/japplphysiol.00757.2023. PMID: 38299223. DOI: 10.1152/japplphysiol.00757.2023

Investigating the Relevance of Maximal Speed and Acceleration in Varsity-Level Female Ice Hockey Players. Gamble, A. S. D., Thompson, K. M. A., Bigg, J. L., Pignanelli, C., Spriet, L. L., & Burr, J. F. (2024). Investigating the Relevance of Maximal Speed and Acceleration in Varsity-Level Female Ice Hockey Players. International journal of sports physiology and performance, 19(5), 496–504. https://doi.org/10.1123/ijspp.2023-0417. PMID: 38503279. DOI: 10.1123/ijspp.2023-0417

A Characterization of the Cardiac Physiology and Aortic Pulse Wave Properties of Artistic Swimmers Across Competitive Levels. Baker, R. E., Cheung, C. P., Coates, A. M., Currie, K. D., King, T. J., Mountjoy, M. L., & Burr, J. F. (2024). A Characterization of the Cardiac Physiology and Aortic Pulse Wave Properties of Artistic Swimmers Across Competitive Levels. Medicine and science in sports and exercise, 10.1249/MSS.0000000000003523. Advance online publication. https://doi.org/10.1249/MSS.0000000000003523. PMID: 39083845. DOI: 10.1249/MSS.0000000000003523

Effect of blood flow restriction and electrical muscle stimulation on human glycemic response to a glucose challenge. Robertson, A. A., Pignanelli, C., & Burr, J. F. (2024). Effect of blood flow restriction and electrical muscle stimulation on human glycemic response to a glucose challenge. European journal of applied physiology, 124(8), 2251–2260. https://doi.org/10.1007/s00421-024-05444-z. PMID: 38441689.
DOI: 10.1007/s00421-024-05444-z

Altered carbohydrate oxidation during exercise in overreached endurance athletes is applicable to training monitoring with continuous glucose monitors. Coates, A. M., Thompson, K. M. A., Grigore, M. M., Baker, R. E., Pignanelli, C., Robertson, A. A., Frangos, S. M., Cheung, C. P., & Burr, J. F. (2024). Altered carbohydrate oxidation during exercise in overreached endurance athletes is applicable to training monitoring with continuous glucose monitors. Scandinavian journal of medicine & science in sports, 34(1), e14551. https://doi.org/10.1111/sms.14551. PMID: 38093477. DOI: 10.1111/sms.14551

Acute oral antioxidant consumption does not alter brachial artery flow mediated dilation in young adults independent of exercise training status. King, T. J., Petrick, H. L., Millar, P. J., & Burr, J. F. (2024). Acute oral antioxidant consumption does not alter brachial artery flow mediated dilation in young adults independent of exercise training status. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 49(3), 375–384. https://doi.org/10.1139/apnm-2023-0218. PMID: 37944127. DOI: 10.1139/apnm-2023-0218

Effects of intensified training with insufficient recovery on joint level and single muscle fibre mechanical function: the role of myofibrillar Ca²⁺ sensitivity. Roussel, O. P., Pignanelli, C., Hubbard, E. F., Coates, A. M., Cheng, A. J., Burr, J. F., & Power, G. A. (2024). Effects of intensified training with insufficient recovery on joint level and single muscle fibre mechanical function: the role of myofibrillar Ca²⁺ sensitivity. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 10.1139/apnm-2024-0189. Advance online publication. https://doi.org/10.1139/apnm-2024-0189. PMID: 39121503.
DOI: 10.1139/apnm-2024-0189

Changes in depression symptoms over 10 years after TBI; a long-term prospective study. Singh, R. K., Humphries, T. J., Dawson, J. F., Tiupin-Szulc, J., Mason, S., & Lecky, F. E. (2024). Changes in depression symptoms over 10 years after TBI; a long-term prospective study. Brain injury, 1–8. Advance online publication. https://doi.org/10.1080/02699052.2024.2413639. PMID: 39396206.
DOI: 10.1080/02699052.2024.2413639

The application of the “inverse problem” method for constructing confining potentials that make N-soliton waveforms exact solutions in the Gross-Pitaevskii equation. Cooper, F., Khare, A., Dawson, J. F., Charalampidis, E. G., & Saxena, A. (2024). The application of the “inverse problem” method for constructing confining potentials that make N-soliton waveforms exact solutions in the Gross-Pitaevskii equation. Chaos (Woodbury, N.Y.), 34(4), 043138. https://doi.org/10.1063/5.0183167. PMID: 38619249.
DOI: 10.1063/5.0183167

Duality in disease: how two amino acid substitutions at actin residue 312 result in opposing forms of cardiomyopathy. Steffensen, K. E., Jones, M. R., Misini, E., King, C. J., Pace, A., & Dawson, J. F. (2024). Duality in disease: how two amino acid substitutions at actin residue 312 result in opposing forms of cardiomyopathy. The Journal of biological chemistry, 107961. Advance online publication. https://doi.org/10.1016/j.jbc.2024.107961. PMID: 39510186. DOI: 10.1016/j.jbc.2024.107961

Novel roles of cardiac-derived erythropoietin in cardiac development and function. Allwood, M. A., Edgett, B. A., Platt, M. J., Marrow, J. P., Coyle-Asbil, B., Holjak, E. J. B., Nelson, V. L., Bangali, S., Alshamali, R., Jacyniak, K., Klein, J. M., Farquharson, L., Romanova, N., Northrup, V., Ogilvie, L. M., Ayoub, A., Ask, K., Vickaryous, M. K., Hare, G. M. T., Brunt, K. R., … Simpson, J. A. (2024). Novel roles of cardiac-derived erythropoietin in cardiac development and function. Journal of molecular and cellular cardiology, 188, 90–104. https://doi.org/10.1016/j.yjmcc.2024.01.006. PMID: 38382296. DOI: 10.1016/j.yjmcc.2024.01.006

The effect of a hiding space on the behaviour and heart rate variability of dairy calves during temporary separation from the dam. Spitzer, H. B., Meagher, R. K., Lynne O’Sullivan, M., Montelpare, W., Gordon, M. B., McKenna, S. L., & Proudfoot, K. L. (2024). The effect of a hiding space on the behaviour and heart rate variability of dairy calves during temporary separation from the dam. Animal welfare (South Mimms, England), 33, e2. https://doi.org/10.1017/awf.2023.100. PMID: 38487788. PMCID: PMC10936337.
DOI: 10.1017/awf.2023.100

Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2.  Teyssier, V., Williamson, C. R., Shata, E., Rosen, S. P., Jones, N., & Bisson, N. (2024). Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2. The Biochemical journal, 481(20), 1411–1435. https://doi.org/10.1042/BCJ20230232. PMID: 39392452.
DOI: 10.1042/BCJ20230232

Reduced Nephrin Tyrosine Phosphorylation Enhances Insulin Secretion and Increases Glucose Tolerance With Age. Williamson, C. R., & Jones, N. (2024). Reduced Nephrin Tyrosine Phosphorylation Enhances Insulin Secretion and Increases Glucose Tolerance With Age. Endocrinology, 165(8), bqae078. https://doi.org/10.1210/endocr/bqae078. PMID: 38954536. PMCID: PMC11247170. DOI: 10.1210/endocr/bqae078

Isometric Exercise Training and Arterial Hypertension: An Updated Review. Edwards, J. J., Coleman, D. A., Ritti-Dias, R. M., Farah, B. Q., Stensel, D. J., Lucas, S. J. E., Millar, P. J., Gordon, B. D. H., Cornelissen, V., Smart, N. A., Carlson, D. J., McGowan, C., Swaine, I., Pescatello, L. S., Howden, R., Bruce-Low, S., Farmer, C. K. T., Leeson, P., Sharma, R., & O’Driscoll, J. M. (2024). Isometric Exercise Training and Arterial Hypertension: An Updated Review. Sports medicine (Auckland, N.Z.), 54(6), 1459–1497. https://doi.org/10.1007/s40279-024-02036-x. PMID: 38762832. PMCID: PMC11239608.
DOI: 10.1007/s40279-024-02036-x

Sympathetic determinants of resting blood pressure in males and females. Nardone, M., Foster, M., O’Brien, M. W., Coovadia, Y., Xie, S., Usselman, C. W., Kimmerly, D. S., Taylor, C. E., & Millar, P. J. (2024). Sympathetic determinants of resting blood pressure in males and females. American journal of physiology. Heart and circulatory physiology, 326(3), H612–H622. https://doi.org/10.1152/ajpheart.00497.2023. PMID: 38214907. DOI: 10.1152/ajpheart.00497.2023

Effects of aerobic exercise on ambulatory blood pressure responses to acute partial sleep deprivation: impact of chronotype and sleep quality. Bommarito, J. C., & Millar, P. J. (2024). Effects of aerobic exercise on ambulatory blood pressure responses to acute partial sleep deprivation: impact of chronotype and sleep quality. American journal of physiology. Heart and circulatory physiology, 326(1), H291–H301. https://doi.org/10.1152/ajpheart.00441.2023. PMID: 38038716. DOI: 10.1152/ajpheart.00441.2023

Consideration of absolute intensity when examining sex differences in blood pressure responses during static exercise. Lee, J. B., & Millar, P. J. (2024). Consideration of absolute intensity when examining sex differences in blood pressure responses during static exercise. American journal of physiology. Regulatory, integrative and comparative physiology, 327(5), R508–R516. https://doi.org/10.1152/ajpregu.00152.2024. PMID: 39250541. DOI: 10.1152/ajpregu.00152.2024

Sympathoinhibition during cardiopulmonary baroreceptor loading is attenuated in older females. Katayama, K., Shiozawa, K., Lee, J. B., Kondo, H., Seo, N., Ishida, K., Millar, P. J., Banno, R., & Ogoh, S. (2024). Sympathoinhibition during cardiopulmonary baroreceptor loading is attenuated in older females. American journal of physiology. Regulatory, integrative and comparative physiology, 327(1), R88–R96. https://doi.org/10.1152/ajpregu.00109.2024. PMID: 38842517. DOI: 10.1152/ajpregu.00109.2024

Workload-indexed blood pressure response to exercise: considerations for future studies estimating maximal oxygen uptake. Rycroft, A. D., Hilton, S. E., Khangura, P. K., Bommarito, J. C., Nardone, M., & Millar, P. J. (2024). Workload-indexed blood pressure response to exercise: considerations for future studies estimating maximal oxygen uptake. European journal of preventive cardiology, 31(12), 1553–1555. https://doi.org/10.1093/eurjpc/zwae071. PMID: 38420870. PMCID: PMC11378264. DOI: 10.1093/eurjpc/zwae071

Influence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals. Katayama, K., Shiozawa, K., Lee, J. B., Seo, N., Kondo, H., Saito, M., Ishida, K., Millar, P. J., Banno, R., & Ogoh, S. (2024). Influence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals. The journal of physiological sciences : JPS, 74(1), 19. https://doi.org/10.1186/s12576-024-00909-4. PMID: 38500058. PMCID: PMC10949681. DOI: 10.1186/s12576-024-00909-4

Intra- and interday reliability of sympathetic transduction to blood pressure in young, healthy adults. Teixeira, A. L., Nardone, M., Fernandes, I. A., Millar, P. J., & Vianna, L. C. (2024). Intra- and interday reliability of sympathetic transduction to blood pressure in young, healthy adults. Journal of applied physiology (Bethesda, Md. : 1985), 136(4), 917–927. https://doi.org/10.1152/japplphysiol.00009.2024. PMID: 38385178.
DOI: 10.1152/japplphysiol.00009.2024

Characteristics associated with responsiveness to isometric handgrip training in medicated hypertensive patients: secondary data analysis. Farah, B. Q., Forjaz, C. L. M., O’Driscoll, J. M., Millar, P. J., Oliveira, M. S., Fecchio, R., Kanegusuku, H., Sousa, J. C. S., Correia, M. A., & Ritti-Dias, R. M. (2024). Characteristics associated with responsiveness to isometric handgrip training in medicated hypertensive patients: secondary data analysis. Journal of hypertension, 42(8), 1421–1426. https://doi.org/10.1097/HJH.0000000000003749. PMID: 38690928. DOI: 10.1097/HJH.0000000000003749.

Relationship between regional sympathetic vascular transduction and sympathetic transduction of blood pressure in young adults at rest. McCarthy, D. G., Nardone, M., Pfundt, K., & Millar, P. J. (2024). Relationship between regional sympathetic vascular transduction and sympathetic transduction of blood pressure in young adults at rest. American journal of physiology. Regulatory, integrative and comparative physiology, 327(6), R528–R533. https://doi.org/10.1152/ajpregu.00199.2024. PMID: 39374083. DOI: 10.1152/ajpregu.00199.2024

Aging in females has minimal effect on changes in celiac artery blood flow during dynamic light-intensity exercise. Shiozawa, K., Saito, M., Lee, J. B., Seo, N., Kondo, H., Kashima, H., Endo, M. Y., Ishida, K., Millar, P. J., & Katayama, K. (2024). Aging in females has minimal effect on changes in celiac artery blood flow during dynamic light-intensity exercise. American journal of physiology. Regulatory, integrative and comparative physiology, 327(1), R14–R24. PMID: 38738294. DOI: 10.1152/ajpregu.00012.2024

Test-retest reliability of exercise blood pressure and the workload-indexed systolic blood pressure slope in healthy males and females. Hilton, S. E., Rycroft, A. D., Matharu, T. S., Khangura, P. K., Bommarito, J. C., Rocha, L. C., Stapleton, R. K., Nardone, M., & Millar, P. J. (2024). Test-retest reliability of exercise blood pressure and the workload-indexed systolic blood pressure slope in healthy males and females. Journal of applied physiology (Bethesda, Md. : 1985), 137(5), 1425–1433. https://doi.org/10.1152/japplphysiol.00493.2024. PMID: 39323394. DOI: 10.1152/japplphysiol.00493.2024

Evaluation of potential novel biomarkers for feline hypertrophic cardiomyopathy. Chong, A., Joshua, J., Raheb, S., Pires, A., Colpitts, M., Caswell, J. L., & Fonfara, S. (2024). Evaluation of potential novel biomarkers for feline hypertrophic cardiomyopathy. Research in veterinary science, 180, 105430. Advance online publication. https://doi.org/10.1016/j.rvsc.2024.105430. PMID: 39395261. DOI: 10.1016/j.rvsc.2024.105430

Effects of hemodynamic load on cardiac remodeling in fish and mammals: the value of comparative models. Shaftoe, J. B., & Gillis, T. E. (2024). Effects of hemodynamic load on cardiac remodeling in fish and mammals: the value of comparative models. The Journal of experimental biology, 227(20), jeb247836. https://doi.org/10.1242/jeb.247836. PMID: 39429041. DOI: 10.1242/jeb.247836

Integrated cellular response of the zebrafish (Danio rerio) heart to temperature change. Shaftoe, J. B., Geddes-McAlister, J., & Gillis, T. E. (2024). Integrated cellular response of the zebrafish (Danio rerio) heart to temperature change. The Journal of experimental biology, 227(20), jeb247522. https://doi.org/10.1242/jeb.247522. PMID: 39091230. DOI: 10.1242/jeb.247522

The influence of triiodothyronine on the immune response and extracellular matrix remodeling during zebrafish heart regeneration. Long, R. R. B., Bullingham, O. M. N., Baylis, B., Shaftoe, J. B., Dutcher, J. R., & Gillis, T. E. (2024). The influence of triiodothyronine on the immune response and extracellular matrix remodeling during zebrafish heart regeneration. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 111769. Advance online publication. https://doi.org/10.1016/j.cbpa.2024.111769. PMID: 39490638. DOI: 10.1016/j.cbpa.2024.111769

Mitochondria from the systemic heart of Pacific hagfish (Eptatretus stoutii) are insensitive to one hour of anoxia followed by reoxygenation. Yutsyschyna, M. A., Shaftoe, J. B., & Gillis, T. E. (2024). Mitochondria from the systemic heart of Pacific hagfish (Eptatretus stoutii) are insensitive to one hour of anoxia followed by reoxygenation. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 275, 111022. Advance online publication. https://doi.org/10.1016/j.cbpb.2024.111022. PMID: 39151663. DOI: 10.1016/j.cbpb.2024.111022

The role of pannexin/purinergic signaling in intervascular communication from capillaries during skeletal muscle contraction in male Golden hamsters. Lamb, I. R., Novielli-Kuntz, N. M., & Murrant, C. L. (2024). The role of pannexin/purinergic signaling in intervascular communication from capillaries during skeletal muscle contraction in male Golden hamsters. Physiological reports, 12(12), e16113. https://doi.org/10.14814/phy2.16113. PMID: 38898485. PMCID: PMC11186745. DOI: 10.14814/phy2.16113

Depletion of dexamethasone in cattle: Food safety study in dairy and beef cattle. Chicoine, A., Renaud, D. L., Enouri, S. S., Dowling, P. M., Gu, Y., & Johnson, R. J. (2024). Depletion of dexamethasone in cattle: Food safety study in dairy and beef cattle. Journal of veterinary pharmacology and therapeutics, 47(2), 80–86. https://doi.org/10.1111/jvp.13409. PMID: 37755169. DOI: 10.1111/jvp.13409

Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats. Tucker, L. E., Sanchez, A., Valverde, A., Blois, S., Monteith, G., Longworth, P., Downie, A., Gu, Y., & Johnson, R. (2024). Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats. Journal of feline medicine and surgery, 26(10), 1098612X241281481. https://doi.org/10.1177/1098612X241281481. PMID: 39475768. PMCID: PMC11529088. DOI: 10.1177/1098612X241281481

Sex Differences in the Neural and Behavioral Effects of Acute High-Dose Edible Cannabis Consumption in Rats. Quansah Amissah, R., Kayir, H., Talhat, M. A., Hassan, A., Gu, Y., Johnson, R., Urban, K., & Khokhar, J. Y. (2024). Sex Differences in the Neural and Behavioral Effects of Acute High-Dose Edible Cannabis Consumption in Rats. The Journal of pharmacology and experimental therapeutics, 391(2), 182–193. https://doi.org/10.1124/jpet.123.001987. PMID: 38844363. DOI: 10.1124/jpet.123.001987

11β-Hydroxysteroid dehydrogenase type 2 may mediate the stress-specific effects of cortisol on brain cell proliferation in adult zebrafish (Danio rerio). Flatt, E. E., & Alderman, S. L. (2024). 11β-Hydroxysteroid dehydrogenase type 2 may mediate the stress-specific effects of cortisol on brain cell proliferation in adult zebrafish (Danio rerio). The Journal of experimental biology, 227(16), jeb248020. https://doi.org/10.1242/jeb.248020. PMID: 39092490. PMCID: PMC11418181. DOI: 10.1242/jeb.248020

Comparison of the diagnostic yield of 3 and 5 mm laparoscopic liver biopsy forceps in cats. Dobberstein, R. E. A., Brisson, B. A., Foster, R. A., Monteith, G., Larose, P. C., Rankovic, A., Verbrugghe, A., & Shoveller, A. K. (2024). Comparison of the diagnostic yield of 3 and 5 mm laparoscopic liver biopsy forceps in cats. Veterinary surgery : VS, 53(2), 302–310. https://doi.org/10.1111/vsu.14049. PMID: 37935060.
DOI: 10.1111/vsu.14049

Development and validation of an LC-MS/MS method for the quantification of oral-sugar probes in plasma to test small intestinal permeability and absorptive capacity in the domestic cat (Felis catus). Patterson, K., Fraser, K., Bernstein, D., Bermingham, E. N., Weidgraaf, K., Kate Shoveller, A., & Thomas, D. (2024). Development and validation of an LC-MS/MS method for the quantification of oral-sugar probes in plasma to test small intestinal permeability and absorptive capacity in the domestic cat (Felis catus). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1242, 124216. https://doi.org/10.1016/j.jchromb.2024.124216. PMID: 38917651.
DOI: 10.1016/j.jchromb.2024.124216

The balance of n-6 and n-3 fatty acids in canine, feline, and equine nutrition: exploring sources and the significance of alpha-linolenic acid. Burron, S., Richards, T., Krebs, G., Trevizan, L., Rankovic, A., Hartwig, S., Pearson, W., Ma, D. W. L., & Shoveller, A. K. (2024). The balance of n-6 and n-3 fatty acids in canine, feline, and equine nutrition: exploring sources and the significance of alpha-linolenic acid. Journal of animal science, 102, skae143. https://doi.org/10.1093/jas/skae143. PMID: 38776363. PMCID: PMC11161904.
DOI: 10.1093/jas/skae143

LHousehold Food Waste Intervention Is Feasible, Acceptable, and Effective. Laila, A., Gallant, M., Bain, M., Alexander, C., Reis, L., Welboren, A., von Massow, M., Parizeau, K., Walton, K., Ma, D. W. L., & Haines, J. (2024). Household Food Waste Intervention Is Feasible, Acceptable, and Effective. Journal of nutrition education and behavior, 56(2), 110–117. https://doi.org/10.1016/j.jneb.2023.11.004. PMID: 38325952.
DOI: 10.1016/j.jneb.2023.11.004

Parental Cooking Confidence is Associated with Children’s Intake of Fish and Seafood. Burns, J. L., PhD, Bhattacharjee, A., Darlington, G., PhD, Haines, J., PhD, Ma, D. W. L., PhD, & The Guelph Family Health Study (2024). Parental Cooking Confidence is Associated with Children’s Intake of Fish and Seafood. Canadian journal of dietetic practice and research : a publication of Dietitians of Canada = Revue canadienne de la pratique et de la recherche en dietetique : une publication des Dietetistes du Canada, 85(1), 54–57. https://doi.org/10.3148/cjdpr-2023-012. PMID: 37403973. DOI: 10.3148/cjdpr-2023-012

Fathers’ use of social media for social comparison is associated with their food parenting practices. Saher, A., Tang, L., Douglas, S., Jacob, R., Walton, K., Sadowski, A., Ma, D. W. L., Haines, J., & Guelph Family Health Study (2024). Fathers’ use of social media for social comparison is associated with their food parenting practices. Appetite, 194, 107201. https://doi.org/10.1016/j.appet.2024.107201. PMID: 38191076. DOI: 10.1016/j.appet.2024.107201

Early life involvement in food skills is associated with children’s cooking skills: a longitudinal analysis. Sahye-Pudaruth, S., Ma, D. W. L., Prashad, M., Haines, J., & Guelph Family Health Study (2024). Early life involvement in food skills is associated with children’s cooking skills: a longitudinal analysis. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 49(5), 718–722. https://doi.org/10.1139/apnm-2023-0497. PMID: 38224581. DOI: 10.1139/apnm-2023-0497

n-3 PUFA ameliorate functional outcomes following repetitive mTBI in the fat-1 mouse model. Lau, J. S., Lust, C. A. C., Lecques, J. D., Hillyer, L. M., Mountjoy, M., Kang, J. X., Robinson, L. E., & Ma, D. W. L. (2024). n-3 PUFA ameliorate functional outcomes following repetitive mTBI in the fat-1 mouse model. Frontiers in nutrition, 11, 1410884. https://doi.org/10.3389/fnut.2024.1410884. PMID: 39070251. MCID: PMC11272621.
DOI: 10.3389/fnut.2024.1410884

The degree of food processing contributes to sugar intakes in families with preschool-aged children. Ashraf, R., Duncan, A. M., Darlington, G., Buchholz, A. C., Haines, J., Ma, D. W. L., & Guelph Family Health Study (2024). The degree of food processing contributes to sugar intakes in families with preschool-aged children. Clinical nutrition ESPEN, 59, 37–47. https://doi.org/10.1016/j.clnesp.2023.11.010. PMID: 38220399. DOI: 10.1016/j.clnesp.2023.11.010

n-3 and n-6 Polyunsaturated Fatty Acids Modulate Macrophage-Myocyte Inflammatory Crosstalk and Improve Myocyte Insulin Sensitivity. Hutchinson, A. L., Liddle, D. M., Monk, J. M., Ma, D. W. L., & Robinson, L. E. (2024). n-3 and n-6 Polyunsaturated Fatty Acids Modulate Macrophage-Myocyte Inflammatory Crosstalk and Improve Myocyte Insulin Sensitivity. Nutrients, 16(13), 2086. https://doi.org/10.3390/nu16132086. PMID: 38999834. PMCID: PMC11243049.
DOI: 10.3390/nu16132086

Dietary Sugar and Anthropometrics among Young Children in the Guelph Family Health Study: Longitudinal Associations. Mahajan, A., PhD, RD, Duncan, A. M., PhD, RD, Darlington, G., PhD, Haines, J., PhD, RD, Ma, D. W. L., PhD, Buchholz, A. C., PhD, RD, & Guelph Family Health Study (2024). Dietary Sugar and Anthropometrics among Young Children in the Guelph Family Health Study: Longitudinal Associations. Canadian journal of dietetic practice and research : a publication of Dietitians of Canada = Revue canadienne de la pratique et de la recherche en dietetique : une publication des Dietetistes du Canada, 85(3), 132–139. https://doi.org/10.3148/cjdpr-2024-001. PMID: 38836464. DOI: 10.3148/cjdpr-2024-001

Correction: Acosta et al. Plant-Based Dietary Indices in Relation to Nutrient and Food Group Intakes in Preschool-Aged Children. Nutrients 2023, 15, 4617. Acosta, P. F. C., Landon, O. A., Ribau, Z. J., Haines, J., Ma, D. W. L., Duncan, A. M., & On Behalf Of The Guelph Family Health Study (2024). Correction: Acosta et al. Plant-Based Dietary Indices in Relation to Nutrient and Food Group Intakes in Preschool-Aged Children. Nutrients 2023, 15, 4617. Nutrients, 16(8), 1186. https://doi.org/10.3390/nu16081186. PMID: 38674940. PMCID: PMC11055010. DOI: 10.3390/nu16081186

Feeding flaxseed to chicken hens changes the size and fatty acid composition of their chicks’ brains. Whittle, R. H., Kiarie, E. G., Ma, D. W. L., & Widowski, T. M. (2024). Feeding flaxseed to chicken hens changes the size and fatty acid composition of their chicks’ brains. Frontiers in physiology, 15, 1400611. https://doi.org/10.3389/fphys.2024.1400611. PMID: 38911324. PMCID: PMC11190958.
DOI: 10.3389/fphys.2024.1400611

Compliance with the 24-hour movement behavior guidelines and the impact of sleep methods among toddler, preschool, and school-aged children enrolled in the Guelph Family Health Study. Coyle-Asbil, H. J., Breau, B., Ma, D. W. L., Haines, J., Buchholz, A. C., Vallis, L. A., & Guelph Family Health Study (2024). Compliance with the 24-hour movement behavior guidelines and the impact of sleep methods among toddler, preschool, and school-aged children enrolled in the Guelph Family Health Study. Journal of science and medicine in sport, 27(9), 631–639. https://doi.org/10.1016/j.jsams.2024.05.014. PMID: 38937183. DOI: 10.1016/j.jsams.2024.05.014

Effect of Lifelong Exposure to Dietary Plant and Marine Sources of n-3 Polyunsaturated Fatty Acids on Morphologic and Gene Expression Biomarkers of Intestinal Health in Early Life. Acosta, J. E., Burns, J. L., Hillyer, L. M., Van, K., Brendel, E. B. K., Law, C., Ma, D. W. L., & Monk, J. M. (2024). Effect of Lifelong Exposure to Dietary Plant and Marine Sources of n-3 Polyunsaturated Fatty Acids on Morphologic and Gene Expression Biomarkers of Intestinal Health in Early Life. Nutrients, 16(5), 719. https://doi.org/10.3390/nu16050719. PMID: 38474847. PMCID: PMC10934214. DOI: 10.3390/nu16050719

Testing a Biobehavioral Model of Chronic Stress and Weight Gain in Young Children (Family Stress Study): Protocol and Baseline Demographics for a Prospective Observational Study. Pare, S. M., Gunn, E., Morrison, K. M., Miller, A. L., Duncan, A. M., Buchholz, A. C., Ma, D. W. L., Tremblay, P. F., Vallis, L. A., Mercer, N. J., & Haines, J. (2024). Testing a Biobehavioral Model of Chronic Stress and Weight Gain in Young Children (Family Stress Study): Protocol and Baseline Demographics for a Prospective Observational Study. JMIR research protocols, 13, e48549. https://doi.org/10.2196/48549. PMID: 38900565.
PMCID: PMC11224706. DOI: 10.2196/48549

Description of the fasted serum metabolomic signature of lean and obese cats at maintenance and of obese cats under energy restriction. Grant, C. E., Godfrey, H., Tal, M., Bakovic, M., Shoveller, A. K., Blois, S. L., Hesta, M., & Verbrugghe, A. (2024). Description of the fasted serum metabolomic signature of lean and obese cats at maintenance and of obese cats under energy restriction. PloS one, 19(3), e0299375. https://doi.org/10.1371/journal.pone.0299375. PMID: 38489282. PMCID: PMC10942044.
DOI: 10.1371/journal.pone.0299375

Exposure to prenatal excess or imbalanced micronutrients leads to long-term perturbations in one-carbon metabolism, trimethylamine-N-oxide and DNA methylation in Wistar rat offspring. Shelp, G. V., Dong, J., Orlov, N. O., Malysheva, O. V., Bender, E., Shoveller, A. K., Bakovic, M., & Cho, C. E. (2024). Exposure to prenatal excess or imbalanced micronutrients leads to long-term perturbations in one-carbon metabolism, trimethylamine-N-oxide and DNA methylation in Wistar rat offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 38(16), e70032. https://doi.org/10.1096/fj.202401018RR. PMID: 39212230. DOI: 10.1096/fj.202401018RR

Methyl donor micronutrients, hypothalamic development and programming for metabolic disease. Kubant, R., Cho, C. E., Pannia, E., Hammoud, R., Yang, N. V., Simonian, R., & Anderson, G. H. (2024). Methyl donor micronutrients, hypothalamic development and programming for metabolic disease. Neuroscience and biobehavioral reviews, 157, 105512. https://doi.org/10.1016/j.neubiorev.2023.105512. PMID: 38128771. DOI: 10.1016/j.neubiorev.2023.105512

Understanding the role of the human gut microbiome in overweight and obesity. McBurney, M. I., & Cho, C. E. (2024). Understanding the role of the human gut microbiome in overweight and obesity. Annals of the New York Academy of Sciences, 1540(1), 61–88. https://doi.org/10.1111/nyas.15215. PMID: 39283061. DOI: 10.1111/nyas.15215

The Effect of Micronutrients on Obese Phenotype of Adult Mice Is Dependent on the Experimental Environment. Yang, Z., Kubant, R., Kranenburg, E., Cho, C. E., & Anderson, G. H. (2024). The Effect of Micronutrients on Obese Phenotype of Adult Mice Is Dependent on the Experimental Environment. Nutrients, 16(5), 696. https://doi.org/10.3390/nu16050696. PMID: 38474824. PMCID: PMC10935069. DOI: 10.3390/nu16050696

Creating your own line: reflections from early career scientists. Bruce, C. D., DuBose, L. E., Tremblay, J. C., Oliveira, B., Islam, H., Teixeira, A. L., Brewster, L. M., Meah, V. L., & Tymko, M. M. (2024). Creating your own line: reflections from early career scientists. Advances in physiology education, 48(1), 49–60. https://doi.org/10.1152/advan.00202.2023. PMID: 38059282. PMCID: PMC11192467 (available on 2025-03-01). DOI: 10.1152/advan.00202.2023

Evidence for direct CO₂ -mediated alterations in cerebral oxidative metabolism in humans. Caldwell, H. G., Hoiland, R. L., Bain, A. R., Howe, C. A., Carr, J. M. J. R., Gibbons, T. D., Durrer, C. G., Tymko, M. M., Stacey, B. S., Bailey, D. M., Sekhon, M. S., MacLeod, D. B., & Ainslie, P. N. (2024). Evidence for direct CO₂ -mediated alterations in cerebral oxidative metabolism in humans. Acta physiologica (Oxford, England), 240(9), e14197. https://doi.org/10.1111/apha.14197. PMID: 38958262. DOI: 10.1111/apha.14197

Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans. Tymko, M. M., Drapeau, A., Vieira-Coelho, M. A., Labrecque, L., Imhoff, S., Coombs, G. B., Langevin, S., Fortin, M., Châteauvert, N., Ainslie, P. N., & Brassard, P. (2024). Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 44(10), 1840–1851. https://doi.org/10.1177/0271678X241248228. PMID: 38613232. DOI: 10.1177/0271678X241248228

Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest. Sekhon, M. S., Stukas, S., Hirsch-Reinshagen, V., Thiara, S., Schoenthal, T., Tymko, M., McNagny, K. M., Wellington, C., & Hoiland, R. (2024). Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest. The Journal of physiology, 602(21), 5731–5744. https://doi.org/10.1113/JP284588. PMID: 37639379. DOI: 10.1113/JP284588

Unveiling the enigma from sick to beauty: Hungry to standardize metrics for dynamic cerebral autoregulation. Tymko M. M. (2024). Unveiling the enigma from sick to beauty: Hungry to standardize metrics for dynamic cerebral autoregulation. Experimental physiology, 109(4), 472–473. https://doi.org/10.1113/EP091781. PMID: 38402582. PMCID: PMC10988677. DOI: 10.1113/EP091781

THC and sperm: Impact on fertilization capability, pre-implantation in vitro development and epigenetic modifications. Kuzma-Hunt, A. G., Sabry, R., Davis, O. S., Truong, V. B., Khokhar, J. Y., & Favetta, L. A. (2024). THC and sperm: Impact on fertilization capability, pre-implantation in vitro development and epigenetic modifications. PloS one, 19(3), e0298697. https://doi.org/10.1371/journal.pone.0298697. PMID: 38536780.
PMCID: PMC10971525. DOI: 10.1371/journal.pone.0298697

Factors influencing JUUL e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters. Frie, J. A., McCunn, P., Eed, A., Hassan, A., Luciani, K. R., Chen, C., Tyndale, R. F., & Khokhar, J. Y. (2024). Factors influencing JUUL e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 49(5), 782–795. https://doi.org/10.1038/s41386-023-01773-3. PMID: 38057369. PMCID: PMC10948865. DOI: 10.1038/s41386-023-01773-3

Behavioral and Pharmacokinetic Assessment of Nicotine e-Cigarette Inhalation in Female Rats. Roeder, N. M., Mihalkovic, A., Richardson, B. J., Penman, S. L., Novalen, M., Hammond, N., Eiden, R., Khokhar, J. Y., Tyndale, R. F., & Thanos, P. K. (2024). Behavioral and Pharmacokinetic Assessment of Nicotine e-Cigarette Inhalation in Female Rats. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 26(6), 724–732. https://doi.org/10.1093/ntr/ntad240. PMID: 38092656.
PMCID: PMC11109488 (available on 2024-12-13). DOI: 10.1093/ntr/ntad240

Genome-wide association studies of lifetime and frequency cannabis use in 131,895 individuals. Thorpe, H. H. A., Fontanillas, P., Meredith, J. J., Jennings, M. V., Cupertino, R. B., Pakala, S., 23andMe Research Team, Elson, S. L., Khokhar, J. Y., Davis, L. K., Johnson, E. C., Palmer, A. A., & Sanchez-Roige, S. (2024). Genome-wide association studies of lifetime and frequency cannabis use in 131,895 individuals. medRxiv : the preprint server for health sciences, 2024.06.14.24308946. https://doi.org/10.1101/2024.06.14.24308946. PMID: 38947071. PMCID: PMC11213095. DOI: 10.1101/2024.06.14.24308946

Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking. Johnson, E. C., Austin-Zimmerman, I., Thorpe, H. H., Levey, D. F., Baranger, D. A., Colbert, S. M., Demontis, D., Khokhar, J. Y., Davis, L. K., Edenberg, H. J., Forti, M. D., Sanchez-Roige, S., Gelernter, J., & Agrawal, A. (2024). Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking. medRxiv : the preprint server for health sciences, 2024.01.17.24301430. https://doi.org/10.1101/2024.01.17.24301430. PMID: 38293235.
PMCID: PMC10827265. DOI: 10.1101/2024.01.17.24301430

Acute nicotine vapor normalizes sensorimotor gating and reduces locomotor activity deficits in HIV-1 transgenic rats. Jha, N. A., Ayoub, S. M., Flesher, M. M., Morton, K., Sikkink, M., de Guglielmo, G., Khokhar, J. Y., Minassian, A., Brody, A. L., & Young, J. W. (2024). Acute nicotine vapor normalizes sensorimotor gating and reduces locomotor activity deficits in HIV-1 transgenic rats. bioRxiv : the preprint server for biology, 2024.06.18.599641. https://doi.org/10.1101/2024.06.18.599641. PMID: 38948796. PMCID: PMC11212989.
DOI: 10.1101/2024.06.18.599641

Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations. Thorpe, H. H. A., Fontanillas, P., Pham, B. K., Meredith, J. J., Jennings, M. V., Courchesne-Krak, N. S., Vilar-Ribó, L., Bianchi, S. B., Mutz, J., 23andMe Research Team, Elson, S. L., Khokhar, J. Y., Abdellaoui, A., Davis, L. K., Palmer, A. A., & Sanchez-Roige, S. (2024). Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 49(10), 1609–1618. https://doi.org/10.1038/s41386-024-01870-x. PMID: 38858598. PMCID: PMC11319477 (available on 2025-09-01). DOI: 10.1038/s41386-024-01870-x

DNA methylation, but not microRNA expression, is affected by in vitro THC exposure in bovine granulosa cells. Floccari, S., Sabry, R., Choux, L., Neal, M. S., Khokhar, J. Y., & Favetta, L. A. (2024). DNA methylation, but not microRNA expression, is affected by in vitro THC exposure in bovine granulosa cells. BMC pharmacology & toxicology, 25(1), 42. https://doi.org/10.1186/s40360-024-00763-5. PMID: 39010179.
PMCID: PMC11247865. DOI: 10.1186/s40360-024-00763-5

Randomized Laboratory Study of Single-Dose Cannabis, Dronabinol, and Placebo in Patients With Schizophrenia and Cannabis Use Disorder. Brunette, M. F., Roth, R. M., Trask, C., Khokhar, J. Y., Ford, J. C., Park, S. H., Hickey, S. M., Zeffiro, T., & Xie, H. (2024). Randomized Laboratory Study of Single-Dose Cannabis, Dronabinol, and Placebo in Patients With Schizophrenia and Cannabis Use Disorder. Schizophrenia bulletin, sbae097. Advance online publication. https://doi.org/10.1093/schbul/sbae097. PMID: 38900958. DOI: 10.1093/schbul/sbae097

Plasma essential amino acid levels in first episode psychosis at baseline and after antipsychotic treatment. Garip, B., Khokhar, J. Y., & Kayir, H. (2024). Plasma essential amino acid levels in first episode psychosis at baseline and after antipsychotic treatment. Schizophrenia (Heidelberg, Germany), 10(1), 103. https://doi.org/10.1038/s41537-024-00528-3. PMID: 39505892. PMCID: PMC11542070.
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Advances in three dimensional metal enhanced fluorescence based biosensors using metal nanomaterial and nano-patterned surfaces. Goodrum, R., & Li, H. (2024). Advances in three dimensional metal enhanced fluorescence based biosensors using metal nanomaterial and nano-patterned surfaces. Biotechnology journal, 19(1), e2300519. https://doi.org/10.1002/biot.202300519. PMID: 37997672. DOI: 10.1002/biot.202300519

Bactericidal Effect and Cytotoxicity of Graphene Oxide/Silver Nanocomposites. Durairaj, S., Sridhar, D., Ströhle, G., Li, H., & Chen, A. (2024). Bactericidal Effect and Cytotoxicity of Graphene Oxide/Silver Nanocomposites. ACS applied materials & interfaces, 16(15), 18300–18310. https://doi.org/10.1021/acsami.3c15798. PMID: 38574271. DOI: 10.1021/acsami.3c15798

Lysis of Extracellular Vesicles and Multiplexed Protein Detection via a Reverse Phase Immunoassay Using a Gold-Nanoparticle-Embedded Membrane Platform. Goodrum, R., & Li, H. (2024). Lysis of Extracellular Vesicles and Multiplexed Protein Detection via a Reverse Phase Immunoassay Using a Gold-Nanoparticle-Embedded Membrane Platform. Langmuir : the ACS journal of surfaces and colloids, 40(42), 22177–22189. https://doi.org/10.1021/acs.langmuir.4c02696. PMID: 39388120. DOI: 10.1021/acs.langmuir.4c02696

Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity. Wu, M., Song, G., Li, J., Song, Z., Zhao, B., Liang, L., Li, W., Hu, H., Tu, H., Li, S., Li, P., Zhang, B., Wang, W., Zhang, Y., Zhang, W., Zheng, W., Wang, J., Wen, Y., Wang, K., Li, A., … Li, H. (2024). Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity. Cell, 187(12), 2935–2951.e19. https://doi.org/10.1016/j.cell.2024.04.027. PMID: 38772371.DOI: 10.1016/j.cell.2024.04.027

Phosphocreatine Promotes Epigenetic Reprogramming to Facilitate Glioblastoma Growth Through Stabilizing BRD2. Chen, L., Qi, Q., Jiang, X., Wu, J., Li, Y., Liu, Z., Cai, Y., Ran, H., Zhang, S., Zhang, C., Wu, H., Cao, S., Mi, L., Xiao, D., Huang, H., Jiang, S., Wu, J., Li, B., Xie, J., Qi, J., … Man, J. (2024). Phosphocreatine Promotes Epigenetic Reprogramming to Facilitate Glioblastoma Growth Through Stabilizing BRD2. Cancer discovery, 14(8), 1547–1565. https://doi.org/10.1158/2159-8290.CD-23-1348. PMID: 38563585.
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Nutrient-delivery and metabolism reactivation therapy for melanoma. Chen, Y., Wang, C., Wu, Y., Wang, Y., Meng, Y., Wu, F., Zhang, H., Cheng, Y. Y., Jiang, X., Shi, J., Li, H., Zhao, P., Wu, J., Zheng, B., Jin, D., & Bu, W. (2024). Nutrient-delivery and metabolism reactivation therapy for melanoma. Nature nanotechnology, 19(9), 1399–1408. https://doi.org/10.1038/s41565-024-01690-6. PMID: 38862714.
DOI: 10.1038/s41565-024-01690-6

Active Magnesium Boride/Alginate Hydrogels Rejuvenate Senescent Cells. Han, Y., Zheng, D., Ji, Y., Feng, Y., Chen, Z., Chen, L., Li, H., Jiang, X., Shen, H., Tao, B., Zhuang, H., & Bu, W. (2024). Active Magnesium Boride/Alginate Hydrogels Rejuvenate Senescent Cells. ACS nano, 18(34), 23566–23578. https://doi.org/10.1021/acsnano.4c07833. PMID: 39145584. DOI: 10.1021/acsnano.4c07833

TGF-β1/SMAD3-driven GLI2 isoform expression contributes to aggressive phenotypes of hepatocellular carcinoma. Ding, J., Yang, Y. Y., Li, P. T., Ma, Y., Zhang, L., Zhou, Y., Jin, C., Li, H. Y., Zhu, Y. F., Liu, X. P., Liu, Z. J., Jia, H. L., Liu, P. G., & Wu, J. (2024). TGF-β1/SMAD3-driven GLI2 isoform expression contributes to aggressive phenotypes of hepatocellular carcinoma. Cancer letters, 588, 216768. https://doi.org/10.1016/j.canlet.2024.216768. PMID: 38453045. DOI: 10.1016/j.canlet.2024.216768

Genetic overlap and causal inferences between diet-derived antioxidants and small-cell lung cancer. Xiao, L., Mo, X., Li, H., Weng, X., Wang, D., & Zhang, W. (2024). Genetic overlap and causal inferences between diet-derived antioxidants and small-cell lung cancer. Medicine, 103(8), e37206. https://doi.org/10.1097/MD.0000000000037206. PMID: 38394493. PMCID: PMC11309643. DOI: 10.1097/MD.0000000000037206

Malonate differentially affects cell survival and confers chemoresistance in cancer cells via the induction of p53-dependent autophagy. Cui, H., Zhu, B., Li, H., Meng, Y., Cai, M., Wang, H., Yuan, M., Zhong, X., Wang, B., Shan, H., Zhe Miao, M., Chai, K., Zheng, J., Zhang, L., & Liu, Y. (2024). Malonate differentially affects cell survival and confers chemoresistance in cancer cells via the induction of p53-dependent autophagy. Biochemical pharmacology, 219, 115950. https://doi.org/10.1016/j.bcp.2023.115950. PMID: 38043718. DOI: 10.1016/j.bcp.2023.115950

Skin-Inspired All-Natural Biogel for Bioadhesive Interface. Lan, L., Ping, J., Li, H., Wang, C., Li, G., Song, J., & Ying, Y. (2024). Skin-Inspired All-Natural Biogel for Bioadhesive Interface. Advanced materials (Deerfield Beach, Fla.), 36(25), e2401151. https://doi.org/10.1002/adma.202401151. PMID: 38558183. DOI: 10.1002/adma.202401151

USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast cancer cell migration and invasion. Tang, K., Yin, T., Deng, B., Wang, M., Ren, Z., Wang, S., Liu, X., Li, H., Wang, J., Du, Y., Zhou, J., Chen, Y., & Wang, Y. (2024). USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast cancer cell migration and invasion. The Journal of biological chemistry, 300(9), 107672. https://doi.org/10.1016/j.jbc.2024.107672. PMID: 39128723. PMCID: PMC11403496.
DOI: 10.1016/j.jbc.2024.107672

Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis. Li, H., Ni, H., Li, Y., Zhou, A., Qin, X., Li, Y., Che, L., Mo, H., Qin, C., & Li, J. (2024). Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis. Cell death discovery, 10(1), 227. https://doi.org/10.1038/s41420-024-01984-7. PMID: 38740747. PMCID: PMC11091123.
DOI: 10.1038/s41420-024-01984-7

Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy. Zhou, S., Li, H., Zhao, C., Zhao, W., Pan, X., Jian, W., & Wang, J. (2024). Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy. International immunopharmacology, 140, 112855. https://doi.org/10.1016/j.intimp.2024.112855. PMID: 39133955.
DOI: 10.1016/j.intimp.2024.112855

VHL suppresses UBE3B-mediated breast tumor growth and metastasis. Wang, S., Li, H., Liu, X., Yin, T., Li, T., Zheng, M., Liu, M., Meng, X., Zhou, J., Wang, Y., & Chen, Y. (2024). VHL suppresses UBE3B-mediated breast tumor growth and metastasis. Cell death & disease, 15(6), 446. https://doi.org/10.1038/s41419-024-06844-x. PMID: 38914543. PMCID: PMC11196597. DOI: 10.1038/s41419-024-06844-x

2023

Advances in 3D metal enhanced fluorescence based biosensors using metal nanomaterial and nano‐patterned surfaces. Goodrum, Rebecca & Li, Huiyan. (2023). Advances in 3D metal enhanced fluorescence based biosensors using metal nanomaterial and nano‐patterned surfaces. Biotechnology Journal. 19. 10.1002/biot.202300519. PMID: 37997672

Intracellular metal enhanced fluorescence utilizing gold nanoparticles embedded in hydrogel droplets for sensitive protein detection in cells. Sebben, David & Li, Huiyan. (2023). Intracellular metal enhanced fluorescence utilizing gold nanoparticles embedded in hydrogel droplets for sensitive protein detection in cells. Talanta Open. 8. 100265. 10.1016/j.talo.2023.100265.

Microarray fabrication techniques for multiplexed bioassay applications Aggarwal, R. T., Lai, L., & Li, H. (2023). Microarray fabrication techniques for multiplexed bioassay applications. Analytical Biochemistry, 683, 115369–115369. https://doi.org/10.1016/j.ab.2023.115369. PMCID: PMC7692379; PMID: 33138051

A digital microfluidic chip with programmable open system actuation and enhanced optical annealing with near‐infrared light Lepard, S., Spotts, I., Brodie, C. H., Leclerc, C. A. A., Eswar, R., Li, H., & Collier, C. M. M. (2023). A digital microfluidic chip with programmable open system actuation and enhanced optical annealing with near-infrared light. Engineering Reports, 6(3). https://doi.org/10.1002/eng2.12737.

Compartmentalized Linker Array: A Scalable and Transferrable Microarray Format for Multiplexed Immunoassays Aggarwal, R., Ferris, B., & Li, H. (2023). Compartmentalized Linker Array: A Scalable and Transferrable Microarray Format for Multiplexed Immunoassays. Analytical Chemistry (Washington), 95(23), 9068–9075. https://doi.org/10.1021/acs.analchem.3c01442. PMID: 37267452

Gold-nanoparticle-embedded hydrogel droplets with enhanced fluorescence for imaging and quantification of proteins in cells Sebben, D., Strohle, G., Roy, P. S., & Li, H. (2023). Gold-nanoparticle-embedded hydrogel droplets with enhanced fluorescence for imaging and quantification of proteins in cells. Mikrochimica Acta (1966), 190(4), 144–144. https://doi.org/10.1007/s00604-023-05728-9. PMID: 36939899

Graphene-based nanostructures from green processes and their applications in biomedical sensors Goodrum, R., Weldekidan, H., Li, H., Mohanty, A. K., & Misra, M. (2024). Graphene-based nanostructures from green processes and their applications in biomedical sensors. Advanced Industrial and Engineering Polymer Research, 7(1), 37–53. https://doi.org/10.1016/j.aiepr.2023.03.001

Comparison of blocking reagents for antibody microarray-based immunoassays on glass and paper membrane substrates Ströhle, G., & Li, H. (2023). Comparison of blocking reagents for antibody microarray-based immunoassays on glass and paper membrane substrates. Analytical and Bioanalytical Chemistry, 415(10), 1967–1977. https://doi.org/10.1007/s00216-023-04614-w. PMID: 36829042

Intracellular Metal Enhanced Fluorescence Utilizing Gold Nanoparticles Embedded in Hydrogel Droplets for Sensitive Protein Detection in Cells Sebben, D., & Li, H. (2023). Intracellular metal enhanced fluorescence utilizing gold nanoparticles embedded in hydrogel droplets for sensitive protein detection in cells. Talanta Open, 8, 100265-. https://doi.org/10.1016/j.talo.2023.100265. PMID: 36939899

Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development. Golding AP, Ferrier B, New LA, et al. Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development. J Mammary Gland Biol Neoplasia. 2023;28(1):19. Published 2023 Jul 21. doi:10.1007/s10911-023-09541-1. PMID: 37479911; PMCID: PMC10361900

Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca²⁺ entry and accelerated differentiation. Hewitt T, Alural B, Tilak M, et al. Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca²⁺ entry and accelerated differentiation. Mol Psychiatry. 2023;28(12):5237-5250. doi:10.1038/s41380-023-02152-6. PMID: 37402854; PMCID: PMC11041787

Uniform-density Bose-Einstein condensates of the Gross-Pitaevskii equation found by solving the inverse problem for the confining potential. Cooper F, Khare A, Dawson JF, Charalampidis EG, Saxena A. Uniform-density Bose-Einstein condensates of the Gross-Pitaevskii equation found by solving the inverse problem for the confining potential. Phys Rev E. 2023;107(6-1):064202. doi:10.1103/PhysRevE.107.064202. PMID: 37464684

Actin’s C-terminus coordinates actin structural changes and functions. Steffensen KE, Dawson JF. Actin’s C-terminus coordinates actin structural changes and functions. Cytoskeleton (Hoboken). 2023;80(9-10):313-329. doi:10.1002/cm.21757. PMID: 37036084

Increasing the calcium sensitivity of muscle using trifluoperazine-induced manipulations in silico, in vitro and in vivo systems Prill K, Jones MR, Steffensen K, Teng GZ, Dawson JF. Increasing the calcium sensitivity of muscle using trifluoperazine-induced manipulations in silico, in vitro and in vivo systems. Arch Biochem Biophys. 2023;735:109521. doi:10.1016/j.abb.2023.109521. PMID: 36657606

Dietary choline, but not L-carnitine, increases circulating lipid and lipoprotein concentrations, without affecting body composition, energy expenditure or respiratory quotient in lean and obese male cats during weight maintenance. Rankovic A, Verton-Shaw S, Shoveller AK, Bakovic M, Kirby G, Verbrugghe A. Dietary choline, but not L-carnitine, increases circulating lipid and lipoprotein concentrations, without affecting body composition, energy expenditure or respiratory quotient in lean and obese male cats during weight maintenance. Front Vet Sci. 2023;10:1198175. Published 2023 Jul 26. doi:10.3389/fvets.2023.1198175. PMID: 37565085; PMCID: PMC10410278

Author Correction: Pcyt2 deficiency causes age-dependent development of nonalcoholic steatohepatitis and insulin resistance that could be attenuated with phosphoethanolamine. Grapentine S, Singh RK, Basu P, et al. Author Correction: Pcyt2 deficiency causes age-dependent development of nonalcoholic steatohepatitis and insulin resistance that could be attenuated with phosphoethanolamine. Sci Rep. 2023;13(1):10175. Published 2023 Jun 22. doi:10.1038/s41598-023-36725-w. PMID: 37349480; PMCID: PMC10287634

Skeletal Muscle Consequences of Phosphatidylethanolamine Synthesis Deficiency. Grapentine S, Singh RK, Bakovic M. Skeletal Muscle Consequences of Phosphatidylethanolamine Synthesis Deficiency. Function (Oxf). 2023;4(4):zqad020. Published 2023 Apr 29. doi:10.1093/function/zqad020. PMID: 37342414; PMCID: PMC10278983

PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing. Cikes D, Elsayad K, Sezgin E, et al. PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing [published correction appears in Nat Metab. 2023 Apr;5(4):711. doi: 10.1038/s42255-023-00791-1]. Nat Metab. 2023;5(3):495-515. doi:10.1038/s42255-023-00766-2. PMID: 36941451

Serum metabolomic analysis of the dose-response effect of dietary choline in overweight male cats fed at maintenance energy requirements. Rankovic A, Godfrey H, Grant CE, et al. Serum metabolomic analysis of the dose-response effect of dietary choline in overweight male cats fed at maintenance energy requirements. PLoS One. 2023;18(1):e0280734. Published 2023 Jan 23. doi:10.1371/journal.pone.0280734. PMID: 36689425; PMCID: PMC9870128

Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation. St Germain M, Iraji R, Bakovic M. Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation. Front Nutr. 2023;9:1094273. Published 2023 Jan 5. doi:10.3389/fnut.2022.1094273. PMID: 36687696; PMCID: PMC9849821

ER stress-associated transcription factor CREB3 is essential for normal Ca²⁺, ATP, and ROS homeostasis. Smith BS, Hewitt T, Bakovic M, Lu R. ER stress-associated transcription factor CREB3 is essential for normal Ca²⁺, ATP, and ROS homeostasis. Mitochondrion. 2023;69:10-17. doi:10.1016/j.mito.2023.01.001. PMID: 36627030

Circulating direct infusion MS and NMR metabolomic profiles of post-gonadectomy kittens with or without additional dietary choline supplementation. Godfrey H, Rankovic A, Grant CE, et al. Circulating direct infusion MS and NMR metabolomic profiles of post-gonadectomy kittens with or without additional dietary choline supplementation. Br J Nutr. 2023;130(3):369-388. doi:10.1017/S0007114522003385. PMID: 36305498; PMCID: PMC10331439

Inhalation of THC-containing cannabis selectively diminishes cardiac autonomic function in humans. Nardone M, Cheung CP, Baker RE, et al. Inhalation of THC-containing cannabis selectively diminishes cardiac autonomic function in humans. Clin Auton Res. 2023;33(6):919-922. doi:10.1007/s10286-023-00993-3. PMID: 37907708

Effects of sex and menstrual cycle phase on celiac artery blood flow during dynamic moderate-intensity leg exercise in young individuals. Shiozawa K, Saito M, Lee JB, et al. Effects of sex and menstrual cycle phase on celiac artery blood flow during dynamic moderate-intensity leg exercise in young individuals. J Appl Physiol (1985). 2023;135(4):956-967. doi:10.1152/japplphysiol.00472.2023. PMID: 37675470

A single high-fat Western meal modulates vascular responsiveness to sympathetic activation at rest and during exercise in humans: a randomized controlled trial. Teixeira AL, Gangat A, Millar PJ. A single high-fat Western meal modulates vascular responsiveness to sympathetic activation at rest and during exercise in humans: a randomized controlled trial. Am J Physiol Heart Circ Physiol. 2023;325(3):H529-H538. doi:10.1152/ajpheart.00283.2023. PMID: 37477687

Higher sympathetic transduction is independently associated with greater very short-term diastolic blood pressure variability in young healthy males and females. O’Brien MW, Nardone M, Foster M, et al. Higher sympathetic transduction is independently associated with greater very short-term diastolic blood pressure variability in young healthy males and females. Clin Auton Res. 2023;33(4):529-532. doi:10.1007/s10286-023-00949-7. PMID: 37243873

Blood Pressure Responses to Postexercise Circulatory Occlusion Are Attenuated After Exercise-Induced Muscle Weakness. Lee JB, Katerberg C, Bommarito JC, Power GA, Millar PJ. Blood Pressure Responses to Postexercise Circulatory Occlusion Are Attenuated After Exercise-Induced Muscle Weakness. Med Sci Sports Exerc. 2023;55(9):1660-1671. PMID: 37017549

Acute hypoxia elicits lasting reductions in the sympathetic action potential transduction of arterial blood pressure in males. Shafer BM, Nardone M, Incognito AV, et al. Acute hypoxia elicits lasting reductions in the sympathetic action potential transduction of arterial blood pressure in males. J Physiol. 2023;601(3):669-687. doi:10.1113/JP283979. PMID: 36542455

Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation. Badrov MB, Keir DA, Tomlinson G, et al. Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation. Eur J Heart Fail. 2023;25(2):201-210. doi:10.1002/ejhf.2749. PMID: 36459000

Folate and Choline: Does It Take Two to Tango in Early Programming of Disease? Chen V, Schwartz JL, Cho CE. Folate and Choline: Does It Take Two to Tango in Early Programming of Disease?. Lifestyle Genom. 2023;16(1):177-191. doi:10.1159/000534452. PMID: 37797585

Micronutrients in High-Fat Diet Modify Insulin Resistance and Its Regulatory Genes in Adult Male Mice. Yang Z, Kubant R, Cho CE, et al. Micronutrients in High-Fat Diet Modify Insulin Resistance and Its Regulatory Genes in Adult Male Mice. Mol Nutr Food Res. 2023;67(18):e2300199. doi:10.1002/mnfr.202300199. PMID: 37526337

Modification of the serotonergic systems and phenotypes by gestational micronutrients. Chen V, Shelp GV, Schwartz JL, Aardema NDJ, Bunnell ML, Cho CE. Modification of the serotonergic systems and phenotypes by gestational micronutrients. J Endocrinol 2023;257(2):e220305. Published 2023 Apr 19. doi:10.1530/JOE-22-0305. PMID: 36930294; PMCID: PMC10160553

Physiological and clinical responses to cycling 7850 km over 85 days in a physically active middle-aged man with idiopathic Parkinson’s disease. Kathia MM, Bommarito JC, Hinks A, et al. Physiological and clinical responses to cycling 7850 km over 85 days in a physically active middle-aged man with idiopathic Parkinson’s disease. Physiol Rep. 2023;11(14):e15772. doi:10.14814/phy2.15772. PMID: 37474301; PMCID: PMC10359154

Renal vascular conductance is unrelated to leg vascular conductance or muscle sympathetic nerve activity at rest and during stress in humans. Teixeira AL, Lee JB, Nardone M, Burr JF, Millar PJ. Renal vascular conductance is unrelated to leg vascular conductance or muscle sympathetic nerve activity at rest and during stress in humans. J Appl Physiol (1985) 2023;135(1):154-164. doi:10.1152/japplphysiol.00673.2022. PMID: 37289954

Time Management Strategies of Rock Climbers in World Cup Bouldering Finals. Mckellar BJ, Coates AM, Cohen JN, Burr JF. Time Management Strategies of Rock Climbers in World Cup Bouldering Finals. J Hum Kinet. 2023;86:165-174. Published 2023 Jan 20. doi:10.5114/jhk/159652. PMID: 37181256; PMCID: PMC10170546

Blood flow restriction does not alter the early hypertrophic signaling and short-term adaptive response to resistance exercise when performed to task failure. Pignanelli C, Holloway GP, Burr JF. Blood flow restriction does not alter the early hypertrophic signaling and short-term adaptive response to resistance exercise when performed to task failure. J Appl Physiol (1985). 2023;134(5):1265-1277. doi:10.1152/japplphysiol.00529.2022. PMID: 37055038

Ischemic Preconditioning Acutely Improves Functional Sympatholysis during Handgrip Exercise in Healthy Males but not Females Teixeira AL, Gangat A, Bommarito JC, Burr JF, Millar PJ. Ischemic Preconditioning Acutely Improves Functional Sympatholysis during Handgrip Exercise in Healthy Males but not Females. Med Sci Sports Exerc. 2023;55(7):1250-1257. doi:10.1249/MSS.0000000000003148. PMID: 36878187

Investigating sensor location on the effectiveness of continuous glucose monitoring during exercise in a non-diabetic population. Coates AM, Cohen JN, Burr JF. Investigating sensor location on the effectiveness of continuous glucose monitoring during exercise in a non-diabetic population. Eur J Sport Sci. 2023;23(10):2109-2117. doi:10.1080/17461391.2023.2174452. PMID: 36715137

Blood flow restriction during high-intensity interval cycling exacerbates psychophysiological responses to a greater extent in females than males. McClean ZJ, Young A, Pohl AJ, et al. Blood flow restriction during high-intensity interval cycling exacerbates psychophysiological responses to a greater extent in females than males. J Appl Physiol (1985). 2023;134(3):596-609. doi:10.1152/japplphysiol.00567.2022. PMID: 36701480

Investigating the roles of exercise intensity and biological sex on postexercise alterations in cardiac function. Coates AM, Millar PJ, Burr JF. Investigating the roles of exercise intensity and biological sex on postexercise alterations in cardiac function. J Appl Physiol (1985). 2023;134(2):455-466. doi:10.1152/japplphysiol.00570.2022. PMID: 36656982

Implementation of the International Olympic Committee Sport Mental Health Assessment Tool 1: Screening for Mental Health Symptoms in a Canadian Multisport University Program. Mountjoy M, Edwards C, Cheung CP, Burr J, Gouttebarge V. Implementation of the International Olympic Committee Sport Mental Health Assessment Tool 1: Screening for Mental Health Symptoms in a Canadian Multisport University Program. Clin J Sport Med. 2023;33(1):5-12. doi:10.1097/JSM.0000000000001077. PMID: 36599359

Ergogenic effect of ischemic preconditioning is not directly conferred to isolated skeletal muscle via blood. Morley WN, Murrant CL, Burr JF. Ergogenic effect of ischemic preconditioning is not directly conferred to isolated skeletal muscle via blood. Eur J Appl Physiol. 2023;123(8):1851-1861. doi:10.1007/s00421-023-05197-1. PMID: 37074464

Cardiac remodeling caused by cold acclimation is reversible with rewarming in zebrafish (Danio rerio). Shaftoe JB, Manchester EA, Gillis TE. Cardiac remodeling caused by cold acclimation is reversible with rewarming in zebrafish (Danio rerio). Comp Biochem Physiol A Mol Integr Physiol. 2023;283:111466. doi:10.1016/j.cbpa.2023.111466. PMID: 37302568

A Revised Perspective on the Evolution of Troponin I and Troponin T Gene Families in Vertebrates. Joyce W, Ripley DM, Gillis T, Black AC, Shiels HA, Hoffmann FG. A Revised Perspective on the Evolution of Troponin I and Troponin T Gene Families in Vertebrates. Genome Biol Evol. 2023;15(1):evac173. doi:10.1093/gbe/evac173. PMID: 36518048; PMCID: PMC9825255

Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults. Parikh K, Shepley BR, Tymko MM, et al. Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults. J Physiol. 2023;601(24):5601-5616. doi:10.1113/JP285265. PMID: 37975212

The effect of hypoxemia on muscle sympathetic nerve activity and cardiovascular function: a systematic review and meta-analysis. Tymko MM, Young D, Vergel D, et al. The effect of hypoxemia on muscle sympathetic nerve activity and cardiovascular function: a systematic review and meta-analysis. Am J Physiol Regul Integr Comp Physiol. 2023;325(5):R474-R489. doi:10.1152/ajpregu.00021.2023. PMID: 37642283

High Altitude-Related Circulating Extracellular Microvesicles Promote a Proinflammatory Endothelial Phenotype In Vitro. Brewster LM, Bain AR, Garcia VP, et al. Global REACH 2018: High Altitude-Related Circulating Extracellular Microvesicles Promote a Proinflammatory Endothelial Phenotype In Vitro. High Alt Med Biol. 2023;24(3):223-229. doi:10.1089/ham.2023.0013. PMID: 37504958

Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction. Hoiland RL, MacLeod DB, Stacey BS, et al. Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction. J Cereb Blood Flow Metab. 2023;43(9):1519-1531. doi:10.1177/0271678X231169579. PMID: 37042194; PMCID: PMC10414015

Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders. Patrician A, Willie C, Hoiland RL, et al. Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders. J Cereb Blood Flow Metab. 2023;43(7):1166-1179. doi:10.1177/0271678X231152734. PMID: 36883428; PMCID: PMC10291452

Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males. Simpson LL, Hansen AB, Moralez G, et al. Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males. Am J Physiol Regul Integr Comp Physiol. 2023;324(4):R457-R469. doi:10.1152/ajpregu.00230.2022. PMID: 36717165; PMCID: PMC10026988

Lifelong exposure to high-altitude hypoxia in humans is associated with improved redox homeostasis and structural-functional adaptations of the neurovascular unit. Stacey BS, Hoiland RL, Caldwell HG, et al. Lifelong exposure to high-altitude hypoxia in humans is associated with improved redox homeostasis and structural-functional adaptations of the neurovascular unit. J Physiol. 2023;601(6):1095-1120. doi:10.1113/JP283362. PMID: 36633375; PMCID: PMC10952731

Circadian medicine: a critical strategy for cardiac care. Sole MJ, Martino TA. Circadian medicine: a critical strategy for cardiac care. Nat Rev Cardiol. 2023;20(11):715-716. doi:10.1038/s41569-023-00925-8. PMID: 37644115;

Cardiovascular research and the arrival of circadian medicine. Martino TA, Delisle BP. Cardiovascular research and the arrival of circadian medicine. Chronobiol Int. 2023;40(1):1-3. doi:10.1080/07420528.2022.2151862. PMID: 37096348; PMCID: PMC11027555

Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension. Gumz ML, Shimbo D, Abdalla M, et al. Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension – 2021 NHLBI Workshop Report. Hypertension. 2023;80(3):503-522. doi:10.1161/HYPERTENSIONAHA.122.19372. PMID: 36448463; PMCID: PMC9931676

Disrupting circadian control of peripheral myogenic reactivity mitigates cardiac injury following myocardial infarction. Kroetsch JT, Lidington D, Alibhai FJ, et al. Disrupting circadian control of peripheral myogenic reactivity mitigates cardiac injury following myocardial infarction. Cardiovasc Res. 2023;119(6):1403-1415. doi:10.1093/cvr/cvac174. PMID: 36418171; PMCID: PMC10262184

2022

A brief morning rest period benefits cardiac repair in pressure overload hypertrophy and postmyocardial infarction.
Reitz CJ, Rasouli M, Alibhai FJ, Khatua TN, Pyle WG, Martino TA. A brief morning rest period benefits cardiac repair in pressure overload hypertrophy and postmyocardial infarction. JCI Insight. 2022 Nov 22;7(22):e164700. doi: 10.1172/jci.insight.164700. PMID: 36256456; PMCID: PMC9746813.
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The Impact of Sex, Circadian Disruption, and the Clock^Δ19/Δ19 Genotype on Alcohol Drinking in Mice.
Rizk AA, Jenkins BW, Al-Sabagh Y, Hamidullah S, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. The Impact of Sex, Circadian Disruption, and the Clock^Δ19/Δ19 Genotype on Alcohol Drinking in Mice. Genes (Basel). 2022 Apr 15;13(4):701. doi: 10.3390/genes13040701. PMID: 35456507; PMCID: PMC9031797.
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Rev-erb α Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice
Al-Sabagh Y, Thorpe HHA, Jenkins BW, Hamidullah S, Talhat MA, Suggett CB, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. Rev-erbα Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice. Int J Mol Sci. 2022 May 6;23(9):5197. doi: 10.3390/ijms23095197. PMID: 35563586; PMCID: PMC9104180.
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Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension – 2021 NHLBI Workshop Report.
Gumz ML, Shimbo D, Abdalla M, Balijepalli RC, Benedict C, Chen Y, Earnest DJ, Gamble KL, Garrison SR, Gong MC, Hogenesch JB, Hong Y, Ivy JR, Joe B, Laposky AD, Liang M, MacLaughlin EJ, Martino TA, Pollock DM, Redline S, Rogers A, Dan Rudic R, Schernhammer ES, Stergiou GS, St-Onge MP, Wang X, Wright J, Oh YS. Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension – 2021 NHLBI Workshop Report. Hypertension. 2023 Mar;80(3):503-522. doi: 10.1161/HYPERTENSIONAHA.122.19372. Epub 2022 Nov 30. PMID: 36448463; PMCID: PMC9931676.– Print Publication

Cardiac Remodeling in Elite Aquatic Sport Athletes. Coates, A. M., Cheung, C. P., Currie, K. D., King, T. J., Mountjoy, M. L., & Burr, J. F. (2022). Cardiac Remodeling in Elite Aquatic Sport Athletes. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 32(5), e485–e491. https://doi.org/10.1097/JSM.0000000000001024. PMID: 36083335. DOI: 10.1097/JSM.0000000000001024

Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans. Cheung, C. P., Nardone, M., Lee, J. B., Baker, R. E., Millar, P. J., & Burr, J. F. (2022). Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans. Circulation, 146(25), 1972–1974. https://doi.org/10.1161/CIRCULATIONAHA.122.062564. PMID: 36314198.
DOI: 10.1161/CIRCULATIONAHA.122.062564

Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology. Badenhorst, C. E., Millet, G. P., Debevec, T., Brocherie, F., Coates, A. M., Burr, J. F., Andersen, A. B., Bejder, J., Gliemann, L., Pedlar, C. R., Brugnara, C., Shiffman, V. J., Peters, C. M., Sheel, A. W., Bruinvels, G., Govus, A. D., Shivgulam, M. E., Petterson, J. L., O’Brien, M. W., Burden, R. J., … Sánchez-Briones, M. E. (2022). Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology. Journal of applied physiology (Bethesda, Md. : 1985), 132(3), 703–709. https://doi.org/10.1152/japplphysiol.00016.2022. PMID: 35274549.
DOI: 10.1152/japplphysiol.00016.2022

Off-Ice Resisted Sprints Best Predict All-Out Skating Performance in Varsity Hockey Players. Thompson, K. M. A., Safadie, A., Ford, J., & Burr, J. F. (2022). Off-Ice Resisted Sprints Best Predict All-Out Skating Performance in Varsity Hockey Players. Journal of strength and conditioning research, 36(9), 2597–2601. https://doi.org/10.1519/JSC.0000000000003861. PMID: 33136771. DOI: 10.1519/JSC.0000000000003861

Relationship of Fitness Combine Results and National Hockey League Performance: A 25-Year Analysis. Cohen, J. N., Thompson, K. M. A., Jamnik, V. K., Gledhill, N., & Burr, J. F. (2022). Relationship of Fitness Combine Results and National Hockey League Performance: A 25-Year Analysis. International journal of sports physiology and performance, 17(6), 908–916. https://doi.org/10.1123/ijspp.2021-0317. PMID: 35245896. DOI: 10.1123/ijspp.2021-0317

Markers of Low Energy Availability in Overreached Athletes: A Systematic Review and Meta-analysis. Kuikman, M. A., Coates, A. M., & Burr, J. F. (2022). Markers of Low Energy Availability in Overreached Athletes: A Systematic Review and Meta-analysis. Sports medicine (Auckland, N.Z.), 52(12), 2925–2941. https://doi.org/10.1007/s40279-022-01723-x. PMID: 35819582. DOI: 10.1007/s40279-022-01723-x

Differences in Left Ventricular Function at Rest and during Isometric Handgrip Exercise in Elite Aquatic Sport Athletes. Coates, A. M., Cheung, C. P., Currie, K. D., King, T. J., Mountjoy, M. L., & Burr, J. F. (2022). Differences in Left Ventricular Function at Rest and during Isometric Handgrip Exercise in Elite Aquatic Sport Athletes. Medicine and science in sports and exercise, 54(3), 507–516. https://doi.org/10.1249/MSS.0000000000002812. PMID: 34690288. DOI: 10.1249/MSS.0000000000002812

Blood flow restriction and stimulated muscle contractions do not improve metabolic or vascular outcomes following glucose ingestion in young, active individuals. Cohen, J. N., Kuikman, M. A., Politis-Barber, V., Stairs, B. E., Coates, A. M., Millar, P. J., & Burr, J. F. (2022). Blood flow restriction and stimulated muscle contractions do not improve metabolic or vascular outcomes following glucose ingestion in young, active individuals. Journal of applied physiology (Bethesda, Md. : 1985), 133(1), 75–86. https://doi.org/10.1152/japplphysiol.00178.2022. PMID: 35608205. DOI: 10.1152/japplphysiol.00178.2022

Reliability and validity of an indoor local positioning system for measuring external load in ice hockey players. Gamble, A. S. D., Bigg, J. L., Pignanelli, C., Nyman, D. L. E., Burr, J. F., & Spriet, L. L. (2023). Reliability and validity of an indoor local positioning system for measuring external load in ice hockey players. European journal of sport science, 23(3), 311–318. https://doi.org/10.1080/17461391.2022.2032371. PMID: 35062856.
DOI: 10.1080/17461391.2022.2032371

Implementation of the International Olympic Committee Sport Mental Health Assessment Tool 1: Screening for Mental Health Symptoms in a Canadian Multisport University Program. International Olympic Committee Sport Mental Health Assessment Tool 1: Screening for Mental Health Symptoms in a Canadian Multisport University Program. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 33(1), 5–12. https://doi.org/10.1097/JSM.0000000000001077. PMID: 36599359. DOI: 10.1097/JSM.0000000000001077

A review of the osteoderms of lizards (Reptilia: Squamata). Williams, C., Kirby, A., Marghoub, A., Kéver, L., Ostashevskaya-Gohstand, S., Bertazzo, S., Moazen, M., Abzhanov, A., Herrel, A., Evans, S. E., & Vickaryous, M. (2022). A review of the osteoderms of lizards (Reptilia: Squamata). Biological reviews of the Cambridge Philosophical Society, 97(1), 1–19. https://doi.org/10.1111/brv.12788. PMID: 34397141.
PMCID: PMC9292694. DOI: 10.1111/brv.12788

Left Atrial Tachycardia and Third-Degree Atrioventricular Block in a Dog. Côté, E., O’Sullivan, M. L., Agarwal, D., & Santilli, R. (2022). Left Atrial Tachycardia and Third-Degree Atrioventricular Block in a Dog. CASE (Philadelphia, Pa.), 6(2), 83–86. https://doi.org/10.1016/j.case.2021.12.001. PMID: 35492289.
PMCID: PMC9050603. DOI: 10.1016/j.case.2021.12.001

Cardiac gene activation varies between young and adult cats and in the presence of hypertrophic cardiomyopathy. Colpitts, M. E., Caswell, J. L., Monteith, G., Joshua, J., O’Sullivan, M. L., Raheb, S., & Fonfara, S. (2022). Cardiac gene activation varies between young and adult cats and in the presence of hypertrophic cardiomyopathy. Research in veterinary science, 152, 38–47. https://doi.org/10.1016/j.rvsc.2022.07.007. PMID: 35917592. DOI: 10.1016/j.rvsc.2022.07.007

Complementary Nck1/2 Signaling in Podocytes Controls α Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition. Martin, C. E., Phippen, N. J., Keyvani Chahi, A., Tilak, M., Banerjee, S. L., Lu, P., New, L. A., Williamson, C. R., Platt, M. J., Simpson, J. A., Krendel, M., Bisson, N., Gingras, A. C., & Jones, N. (2022). Complementary Nck1/2 Signaling in Podocytes Controls α Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition. Journal of the American Society of Nephrology : JASN, 33(8), 1546–1567. https://doi.org/10.1681/ASN.2021101343. PMID: 35906089. PMCID: PMC9342632. DOI: 10.1681/ASN.2021101343

Sex Differences in Glomerular Protein Expression and Effects of Soy-Based Diet on Podocyte Signaling. Mahesaniya, A., Williamson, C. R., Keyvani Chahi, A., Martin, C. E., Mitro, A. E., Lu, P., New, L. A., Watson, K. L., Moorehead, R. A., & Jones, N. (2022). Sex Differences in Glomerular Protein Expression and Effects of Soy-Based Diet on Podocyte Signaling. Canadian journal of kidney health and disease, 9, 20543581221121636. https://doi.org/10.1177/20543581221121636. PMID: 36199279. MCID: PMC9528100. DOI: 10.1177/20543581221121636

Investigation and analysis of microplastics in sewage sludge and biosolids: A case study from one wastewater treatment works in the UK. Harley-Nyang, D., Memon, F. A., Jones, N., & Galloway, T. (2022). Investigation and analysis of microplastics in sewage sludge and biosolids: A case study from one wastewater treatment works in the UK. The Science of the total environment, 823, 153735. https://doi.org/10.1016/j.scitotenv.2022.153735. PMID: 35149057. DOI: 10.1016/j.scitotenv.2022.153735

Involving Patient Partners in the KRESCENT Peer Review: Intent, Process, Challenges, and Opportunities. Fowler, E. A., Bell, K., Burns, K., Chiazzese, A., DeSerres, S. A., Foster, B. J., Hartwig, S., Herrington, G., James, M. T., Jensen, V., Jones, N., Kidston, S., Lemay, S., Levin, A., MacPhee, A., McCutcheon, S., Ravani, P., Samuel, S., Scholey, J., Takano, T., … Clase, C. M. (2022). Involving Patient Partners in the KRESCENT Peer Review: Intent, Process, Challenges, and Opportunities. Canadian journal of kidney health and disease, 9, 20543581221136402. https://doi.org/10.1177/20543581221136402. PMID: 36406869. MCID: PMC9669682
DOI: 10.1177/20543581221136402

Ingested plastics in beach-washed Fairy Prions Pachyptila turtur from Tasmania. Lavers, J. L., de Jersey, A. M., Jones, N. R., Stewart, L. G., Charlton-Howard, H. S., Grant, M. L., & Woehler, E. J. (2022). Ingested plastics in beach-washed Fairy Prions Pachyptila turtur from Tasmania. Marine pollution bulletin, 184, 114096. https://doi.org/10.1016/j.marpolbul.2022.114096. PMID: 36113176. DOI: 10.1016/j.marpolbul.2022.114096

Reply to Fadel et al. Nardone, M., Vianna, L. C., & Millar, P. J. (2022). Reply to Fadel et al. American journal of physiology. Regulatory, integrative and comparative physiology, 322(2), R123–R125. https://doi.org/10.1152/ajpregu.00265.2021. PMID: 35043690. DOI: 10.1152/ajpregu.00265.2021

Elevated muscle sympathetic activity in former smokers with heart failure. Incognito, A. V., Murai, H., Hamaoka, T., Sugimoto, H., Millar, P. J., & Takamura, M. (2022). Elevated muscle sympathetic activity in former smokers with heart failure. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 32(2), 151–154. https://doi.org/10.1007/s10286-022-00857-2. PMID: 35182279.
DOI: 10.1007/s10286-022-00857-2

Autonomic modulation in heart failure patients by cardiopulmonary rehabilitation: who benefits? Notarius, C. F., Keir, D. A., Badrov, M. B., Millar, P. J., Oh, P., & Floras, J. S. (2022). Autonomic modulation in heart failure patients by cardiopulmonary rehabilitation: who benefits?. European journal of preventive cardiology, 29(12), 1699–1702. https://doi.org/10.1093/eurjpc/zwac106. PMID: 35653370.
DOI: 10.1093/eurjpc/zwac106

Lower sympathetic transduction of blood pressure in uncontrolled hypertensives: physiological adaptation, methodological limitation, or both? Nardone, M., & Millar, P. J. (2022). Lower sympathetic transduction of blood pressure in uncontrolled hypertensives: physiological adaptation, methodological limitation, or both?. Journal of human hypertension, 36(4), 423–424. https://doi.org/10.1038/s41371-021-00638-w. PMID: 34795392. DOI: 10.1038/s41371-021-00638-w

Upper and lower limb muscle sympathetic responses to contralateral exercise in healthy humans: A pilot study. Lee, J. B., Katayama, K., & Millar, P. J. (2022). Upper and lower limb muscle sympathetic responses to contralateral exercise in healthy humans: A pilot study. Autonomic neuroscience : basic & clinical, 243, 103024. https://doi.org/10.1016/j.autneu.2022.103024. PMID: 36108469. DOI: 10.1016/j.autneu.2022.103024

Attenuated Sympathetic Blood Pressure Transduction in Patients With Treated Heart Failure With Reduced Ejection Fraction. Nardone, M., Notarius, C. F., Badrov, M. B., Millar, P. J., & Floras, J. S. (2022). Attenuated Sympathetic Blood Pressure Transduction in Patients With Treated Heart Failure With Reduced Ejection Fraction. Hypertension (Dallas, Tex. : 1979), 79(12), 2764–2773. https://doi.org/10.1161/HYPERTENSIONAHA.122.19850. PMID: 36252088.
DOI: 10.1161/HYPERTENSIONAHA.122.19850

Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia-induced sympathetic long-term facilitation. Shafer, B. M., Incognito, A. V., Vermeulen, T. D., Nardone, M., Teixeira, A. L., Klassen, S. A., Millar, P. J., & Foster, G. E. (2022). Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia-induced sympathetic long-term facilitation. The Journal of physiology, 600(13), 3127–3147. https://doi.org/10.1113/JP282933. PMID: 35661360.
DOI: 10.1113/JP282933

Sympathetic transduction of blood pressure during graded lower body negative pressure in young healthy adults. Nardone, M., Katerberg, C., Teixeira, A. L., Lee, J. B., Bommarito, J. C., & Millar, P. J. (2022). Sympathetic transduction of blood pressure during graded lower body negative pressure in young healthy adults. American journal of physiology. Regulatory, integrative and comparative physiology, 322(6), R620–R628. https://doi.org/10.1152/ajpregu.00034.2022. PMID: 35470697.
DOI: 10.1152/ajpregu.00034.2022

Influence of sex and age on the relationship between aerobic fitness and muscle sympathetic nerve activity in healthy adults. Badrov, M. B., Keir, D. A., Notarius, C. F., O’Donnell, E., Millar, P. J., Kimmerly, D. S., Shoemaker, J. K., & Floras, J. S. (2022). Influence of sex and age on the relationship between aerobic fitness and muscle sympathetic nerve activity in healthy adults. American journal of physiology. Heart and circulatory physiology, 323(5), H934–H940. https://doi.org/10.1152/ajpheart.00450.2022. PMID: 36206052.
DOI: 10.1152/ajpheart.00450.2022

Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation. Badrov, M. B., Keir, D. A., Tomlinson, G., Notarius, C. F., Millar, P. J., Kimmerly, D. S., Shoemaker, J. K., Keys, E., & Floras, J. S. (2023). Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation. European journal of heart failure, 25(2), 201–210. https://doi.org/10.1002/ejhf.2749. PMID: 36459000. DOI: 10.1002/ejhf.2749

Assessing functional sympatholysis during rhythmic handgrip exercise using Doppler ultrasound and near-infrared spectroscopy: sex differences and test-retest reliability. Teixeira, A. L., Garland, M., Lee, J. B., Nardone, M., & Millar, P. J. (2022). Assessing functional sympatholysis during rhythmic handgrip exercise using Doppler ultrasound and near-infrared spectroscopy: sex differences and test-retest reliability. American journal of physiology. Regulatory, integrative and comparative physiology, 323(5), R810–R821. https://doi.org/10.1152/ajpregu.00123.2022. PMID: 36189987.
DOI: 10.1152/ajpregu.00123.2022

Potentiation of GABAergic synaptic transmission by diazepam acutely increases resting beat-to-beat blood pressure variability in young adults. Teixeira, A. L., Nardone, M., Samora, M., Fernandes, I. A., Ramos, P. S., Sabino-Carvalho, J. L., Ricardo, D. R., Millar, P. J., & Vianna, L. C. (2022). Potentiation of GABAergic synaptic transmission by diazepam acutely increases resting beat-to-beat blood pressure variability in young adults. American journal of physiology. Regulatory, integrative and comparative physiology, 322(6), R501–R510. https://doi.org/10.1152/ajpregu.00291.2021. PMID: 35348021. DOI: 10.1152/ajpregu.00291.2021

Naturally Occurring Antioxidant Therapy in Alzheimer’s Disease. Collins, A. E., Saleh, T. M., & Kalisch, B. E. (2022). Naturally Occurring Antioxidant Therapy in Alzheimer’s Disease. Antioxidants (Basel, Switzerland), 11(2), 213. https://doi.org/10.3390/antiox11020213. PMID: 35204096. PMCID: PMC8868221. DOI: 10.3390/antiox11020213

VANL-100 Attenuates Beta-Amyloid-Induced Toxicity in SH-SY5Y Cells. Collins, A. E., Saleh, T. M., & Kalisch, B. E. (2022). VANL-100 Attenuates Beta-Amyloid-Induced Toxicity in SH-SY5Y Cells. International journal of molecular sciences, 24(1), 442. https://doi.org/10.3390/ijms24010442. PMID: 36613883. PMCID: PMC9820495.
DOI: 10.3390/ijms24010442

Hemorrhagic Resuscitation Guided by Viscoelastography in Far-Forward Combat and Austere Civilian Environments: Goal-Directed Whole-Blood and Blood-Component Therapy Far from the Trauma Center. Lantry, J. H., Mason, P., Logsdon, M. G., Bunch, C. M., Peck, E. E., Moore, E. E., Moore, H. B., Neal, M. D., Thomas, S. G., Khan, R. Z., Gillespie, L., Florance, C., Korzan, J., Preuss, F. R., Mason, D., Saleh, T., Marsee, M. K., Vande Lune, S., Ayoub, Q., Fries, D., … Walsh, M. M. (2022). Hemorrhagic Resuscitation Guided by Viscoelastography in Far-Forward Combat and Austere Civilian Environments: Goal-Directed Whole-Blood and Blood-Component Therapy Far from the Trauma Center. Journal of clinical medicine, 11(2), 356. https://doi.org/10.3390/jcm11020356. PMID: 35054050. PMCID: PMC8778082.
DOI: 10.3390/jcm11020356

Influence of staple line number and configuration on the leakage of small intestinal functional end-to-end stapled anastomosis: An ex vivo study. Quitzan, J. G., Singh, A., Beaufrère, H., & Saleh, T. M. (2022). Influence of staple line number and configuration on the leakage of small intestinal functional end-to-end stapled anastomosis: An ex vivo study. Veterinary surgery : VS, 51(5), 781–787. https://doi.org/10.1111/vsu.13818. PMID: 35500144. DOI: 10.1111/vsu.13818

Feline hypertrophic cardiomyopathy: reduced microvascular density and involvement of CD34+ interstitial cells. Rodríguez, J. M. M., Fonfara, S., Hetzel, U., & Kipar, A. (2022). Feline hypertrophic cardiomyopathy: reduced microvascular density and involvement of CD34+ interstitial cells. Veterinary pathology, 59(2), 269–283. https://doi.org/10.1177/03009858211062631. PMID: 34955067. PMCID: PMC8928422.
DOI: 10.1177/03009858211062631

Transcutaneous Cervical Vagus Nerve Stimulation Induces Changes in the Electroencephalogram and Heart Rate Variability of Healthy Dogs, a Pilot Study. Castillo, G., Gaitero, L., Fonfara, S., Czura, C. J., Monteith, G., & James, F. (2022). Transcutaneous Cervical Vagus Nerve Stimulation Induces Changes in the Electroencephalogram and Heart Rate Variability of Healthy Dogs, a Pilot Study. Frontiers in veterinary science, 9, 878962. https://doi.org/10.3389/fvets.2022.878962. PMID: 35769324. PMCID: PMC9234651
DOI: 10.3389/fvets.2022.878962

Age matters: Comparing life-stage responses to diluted bitumen exposure in coho salmon (Oncorhynchus kisutch). Perugini, G., Edgar, M., Lin, F., Kennedy, C. J., Farrell, A. P., Gillis, T. E., & Alderman, S. L. (2022). Age matters: Comparing life-stage responses to diluted bitumen exposure in coho salmon (Oncorhynchus kisutch). Aquatic toxicology (Amsterdam, Netherlands), 253, 106350. https://doi.org/10.1016/j.aquatox.2022.106350. PMID: 36370651. DOI: 10.1016/j.aquatox.2022.106350

Regulation of collagen deposition in the trout heart during thermal acclimation. Johnston, E. F., & Gillis, T. E. (2022). Regulation of collagen deposition in the trout heart during thermal acclimation. Current research in physiology, 5, 99–108. https://doi.org/10.1016/j.crphys.2022.02.004. PMID: 35243359. PMCID: PMC8857596
DOI: 10.1016/j.crphys.2022.02.004

Diluted Bitumen Affects Multiple Physiological Systems in Sockeye Salmon (Oncorhynchus nerka) Embryo to Juvenile Life Stages. Lin, F., Alderman, S. L., Gillis, T. E., & Kennedy, C. J. (2022). Diluted Bitumen Affects Multiple Physiological Systems in Sockeye Salmon (Oncorhynchus nerka) Embryo to Juvenile Life Stages. Environmental toxicology and chemistry, 41(8), 1937–1949. https://doi.org/10.1002/etc.5362. PMID: 35596707. DOI: 10.1002/etc.5362

Capillary communication: the role of capillaries in sensing the tissue environment, coordinating the microvascular, and controlling blood flow. Murrant, C. L., & Fletcher, N. M. (2022). Capillary communication: the role of capillaries in sensing the tissue environment, coordinating the microvascular, and controlling blood flow. American journal of physiology. Heart and circulatory physiology, 323(5), H1019–H1036. https://doi.org/10.1152/ajpheart.00088.2022. PMID: 36149771.
DOI: 10.1152/ajpheart.00088.2022

Dietary nitrate increases submaximal SERCA activity and ADP transfer to mitochondria in slow-twitch muscle of female mice. Petrick, H. L., Brownell, S., Vachon, B., Brunetta, H. S., Handy, R. M., van Loon, L. J. C., Murrant, C. L., & Holloway, G. P. (2022). Dietary nitrate increases submaximal SERCA activity and ADP transfer to mitochondria in slow-twitch muscle of female mice. American journal of physiology. Endocrinology and metabolism, 323(2), E171–E184. https://doi.org/10.1152/ajpendo.00371.2021. PMID: 35732003. DOI: 10.1152/ajpendo.00371.2021

Network analysis of Standardbred horse movements between racetracks in Canada and the United States in 2019: Implications for disease spread and control. Brown, J., Physick-Sheard, P., Greer, A., & Poljak, Z. (2022). Network analysis of Standardbred horse movements between racetracks in Canada and the United States in 2019: Implications for disease spread and control. Preventive veterinary medicine, 204, 105643. https://doi.org/10.1016/j.prevetmed.2022.105643. PMID: 35462328. DOI: 10.1016/j.prevetmed.2022.105643

Pharmacokinetics of combined administration of iron dextran with meloxicam or flunixin meglumine in piglets. Enouri, S. S., O’Sullivan, T. L., Ramkissoon, S., Friendship, R. M., Gu, Y., & Johnson, R. J. (2022). Pharmacokinetics of combined administration of iron dextran with meloxicam or flunixin meglumine in piglets. The Canadian veterinary journal = La revue veterinaire canadienne, 63(7), 727–734. PMID: 35784780. PMCID: PMC9207966

Disruption of targeted muscle reinnervation due to heterotopic ossification in an amputated lower extremity. Anderson, S. R., Gupta, N., Johnson, E. A., & Johnson, R. M. (2022). Disruption of targeted muscle reinnervation due to heterotopic ossification in an amputated lower extremity. BMJ case reports, 15(5), e249705. https://doi.org/10.1136/bcr-2022-249705. PMID: 35568417.
PMCID: PMC9109042. DOI: 10.1136/bcr-2022-249705

Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis. Ströhle, G., Gan, J., & Li, H. (2022). Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis. Analytical and bioanalytical chemistry, 414(24), 7051–7067. https://doi.org/10.1007/s00216-022-04178-1. PMID: 35732746. DOI: 10.1007/s00216-022-04178-1

In-silico selection of cancer blood plasma proteins by integrating genomic and proteomic databases. Chatterjee, G., Ferris, B., Momenbeitollahi, N., & Li, H. (2022). In-silico selection of cancer blood plasma proteins by integrating genomic and proteomic databases. Proteomics, 22(4), e2100230. https://doi.org/10.1002/pmic.202100230. PMID: 34933412. DOI: 10.1002/pmic.202100230

Hydrogel Stamping for Rapid, Multiplexed, Point-of-Care Immunostaining of Cells and Tissues. Chin, L. K., Li, H., Choi, J. H., Iwamoto, Y., Oh, J., Min, J., Beak, S. K., Yoo, D., Castro, C. M., Lee, D., & Im, H. (2022). Hydrogel Stamping for Rapid, Multiplexed, Point-of-Care Immunostaining of Cells and Tissues. ACS applied materials & interfaces, 14(24), 27613–27622. https://doi.org/10.1021/acsami.2c05071. PMID: 35671240. DOI: 10.1021/acsami.2c05071

Extracellular Vesicle (EV) Dot Blotting for Multiplexed EV Protein Detection in Complex Biofluids. Momenbeitollahi, N., Aggarwal, R., Strohle, G., Bouriayee, A., & Li, H. (2022). Extracellular Vesicle (EV) Dot Blotting for Multiplexed EV Protein Detection in Complex Biofluids. Analytical chemistry, 94(20), 7368–7374. https://doi.org/10.1021/acs.analchem.2c00846. PMID: 35533397. DOI: 10.1021/acs.analchem.2c00846

Entrapping gold nanoparticles in membranes for simple-to-use enhanced fluorescence detection of proteins. Momenbeitollahi, N., van der Zalm, J., Chen, A., & Li, H. (2022). Entrapping gold nanoparticles in membranes for simple-to-use enhanced fluorescence detection of proteins. Analytica chimica acta, 1195, 339443. https://doi.org/10.1016/j.aca.2022.339443. PMID: 35090665. DOI: 10.1016/j.aca.2022.339443

Intensity-Varied Closed-Loop Noise Stimulation for Oscillation Suppression in the Parkinsonian State. Yu, H., Meng, Z., Li, H., Liu, C., & Wang, J. (2022). Intensity-Varied Closed-Loop Noise Stimulation for Oscillation Suppression in the Parkinsonian State. IEEE transactions on cybernetics, 52(9), 9861–9870. https://doi.org/10.1109/TCYB.2021.3079100. PMID: 34398769. DOI: 10.1109/TCYB.2021.3079100

Methods for Enhanced Fluorescence Detection of Proteins by using Entrapped Gold Nanoparticles in Membranes. Momenbeitollahi, N., van der Zalm, J., Chen, A., & Li, H. (2022). Methods for Enhanced Fluorescence Detection of Proteins by using Entrapped Gold Nanoparticles in Membranes. Current protocols, 2(3), e404. https://doi.org/10.1002/cpz1.404. PMID: 35333454. DOI: 10.1002/cpz1.404

Cardiac gene activation varies between young and adult cats and in the presence of hypertrophic cardiomyopathy. Colpitts, M. E., Caswell, J. L., Monteith, G., Joshua, J., O’Sullivan, M. L., Raheb, S., & Fonfara, S. (2022). Cardiac gene activation varies between young and adult cats and in the presence of hypertrophic cardiomyopathy. Research in veterinary science, 152, 38–47. https://doi.org/10.1016/j.rvsc.2022.07.007. PMID: 35917592. DOI: 10.1016/j.rvsc.2022.07.007

A case of tail-biting on a multi-site swine operation in Ontario. Henry, M., O’Sullivan, T. L., Shoveller, A. K., Niel, L., & Friendship, R. M. (2022). A case of tail-biting on a multi-site swine operation in Ontario. The Canadian veterinary journal = La revue veterinaire canadienne, 63(8), 835–840. PMID: 35919461.
PMCID: PMC9281881

Effect of Varying Levels of Dietary Tryptophan on Aggression and Abnormal Behavior in Growing Pigs. Henry, M., Shoveller, A. K., O’Sullivan, T. L., Niel, L., & Friendship, R. (2022). Effect of Varying Levels of Dietary Tryptophan on Aggression and Abnormal Behavior in Growing Pigs. Frontiers in veterinary science, 9, 849970. https://doi.org/10.3389/fvets.2022.849970. PMID: 35720838. PMCID: PMC9198587
DOI: 10.3389/fvets.2022.849970

Circulating direct infusion MS and NMR metabolomic profiles of post-gonadectomy kittens with or without additional dietary choline supplementation. Godfrey, H., Rankovic, A., Grant, C. E., Abood, S. K., Shoveller, A. K., Bakovic, M., & Verbrugghe, A. (2023). Circulating direct infusion MS and NMR metabolomic profiles of post-gonadectomy kittens with or without additional dietary choline supplementation. The British journal of nutrition, 130(3), 369–388. https://doi.org/10.1017/S0007114522003385. PMID: 36305498. PMCID: PMC10331439
DOI: 10.1017/S0007114522003385

Dietary choline in gonadectomized kittens improved food intake and body composition but not satiety, serum lipids, or energy expenditure. Godfrey, H., Rankovic, A., Grant, C. E., Shoveller, A. K., Bakovic, M., Abood, S. K., & Verbrugghe, A. (2022). Dietary choline in gonadectomized kittens improved food intake and body composition but not satiety, serum lipids, or energy expenditure. PloS one, 17(3), e0264321. https://doi.org/10.1371/journal.pone.0264321. PMID: 35298484. PMCID: PMC8929592
DOI: 10.1371/journal.pone.0264321

Comparative protein quality in black soldier fly larvae meal vs. soybean meal and fish meal using classical protein efficiency ratio (PER) chick growth assay model. Cheng, V., Shoveller, A. K., Huber, L. A., & Kiarie, E. G. (2023). Comparative protein quality in black soldier fly larvae meal vs. soybean meal and fish meal using classical protein efficiency ratio (PER) chick growth assay model. Poultry science, 102(1), 102255. https://doi.org/10.1016/j.psj.2022.102255. PMID: 36343434. PMCID: PMC9646975.
DOI: 10.1016/j.psj.2022.102255

Breakfast Quality of Preschool-aged Canadian Children. Smith, E. K., Lewis, R., Buchholz, A. C., Haines, J., Ma, D. W. L., & Duncan, A. M. (2023). Breakfast Quality of Preschool-aged Canadian Children. Canadian journal of dietetic practice and research : a publication of Dietitians of Canada = Revue canadienne de la pratique et de la recherche en dietetique : une publication des Dietetistes du Canada, 84(1), 58–61. https://doi.org/10.3148/cjdpr-2022-023. PMID: 36004742. DOI: 10.3148/cjdpr-2022-023

Short communication: Tissue distribution of major cannabinoids following intraperitoneal injection in male rats. Lust, C. A. C., Lin, X., Rock, E. M., Limebeer, C. L., Parker, L. A., & Ma, D. W. L. (2022). Short communication: Tissue distribution of major cannabinoids following intraperitoneal injection in male rats. PloS one, 17(1), e0262633. https://doi.org/10.1371/journal.pone.0262633. PMID: 35045097.
PMCID: PMC8769355. DOI: 10.1371/journal.pone.0262633

Cheese Intake is Inversely Associated with LDL Cholesterol in Young Children. Sheremeta, J., Ma, D. W. L., Haines, J., Duncan, A. M., Darlington, G., Newton, G., Buchholz, A. C., & Guelph Family Health Study (2022). Cheese Intake is Inversely Associated with LDL Cholesterol in Young Children. Canadian journal of dietetic practice and research : a publication of Dietitians of Canada = Revue canadienne de la pratique et de la recherche en dietetique : une publication des Dietetistes du Canada, 83(4), 208–211. https://doi.org/10.3148/cjdpr-2022-012. PMID: 35503897.
DOI: 10.3148/cjdpr-2022-012

Knowledge and perceptions of the 2019 Canada’s Food Guide: a qualitative study with Canadian children. Zhang, F., Laila, A., Leme, A. C. B., Ma, D. W. L., & Haines, J. (2022). Knowledge and perceptions of the 2019 Canada’s Food Guide: a qualitative study with Canadian children. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 47(11), 1096–1103. https://doi.org/10.1139/apnm-2022-0271. PMID: 36095331. DOI: 10.1139/apnm-2022-0271

Non-Nutritive Sweetener Intake Is Low in Preschool-Aged Children in the Guelph Family Health Pilot Study. Mahajan, A., Haines, J., Carriero, A., Hogan, J. L., Yu, J., Buchholz, A. C., Duncan, A. M., Darlington, G., Ma, D. W. L., & On Behalf Of The Guelph Family Health Study (2022). Non-Nutritive Sweetener Intake Is Low in Preschool-Aged Children in the Guelph Family Health Pilot Study. Nutrients, 14(10), 2091. https://doi.org/10.3390/nu14102091. PMID: 35631232. PMCID: PMC9145788.
DOI: 10.3390/nu14102091

Intakes of PUFA are low in preschool-aged children in the Guelph Family Health Study pilot cohort. Burns, J. L., Mirotta, J. A., Duncan, A. M., Darlington, G., Haines, J., Shivappa, N., Hébert, J. R., Ma, D. W. L., & The Guelph Family Health Study (2022). Intakes of PUFA are low in preschool-aged children in the Guelph Family Health Study pilot cohort. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 47(9), 973–978. https://doi.org/10.1139/apnm-2021-0618. PMID: 35649282. DOI: 10.1139/apnm-2021-0618

Comparing the perceptions and opinions of the 2007 and 2019 Canada’s food guides among parents of young children. Ramuscak, A. V., Ma, D. W. L., Forbes, L. E., Duncan, A. M., Sadowski, A., & Haines, J. (2022). Comparing the perceptions and opinions of the 2007 and 2019 Canada’s food guides among parents of young children. Frontiers in public health, 10, 944648. https://doi.org/10.3389/fpubh.2022.944648. PMID: 36016900. PMCID: PMC9395618.
DOI: 10.3389/fpubh.2022.944648

Δ5 and Δ6 desaturase indices are not associated with zinc intake as determined by dietary assessment or modified by a zinc-FADS1 rs174547 SNP interaction in young Canadian adults. LeMoire, A., Abdelmagid, S., Ma, D. W. L., El-Sohemy, A., & Mutch, D. M. (2022). Δ5 and Δ6 desaturase indices are not associated with zinc intake as determined by dietary assessment or modified by a zinc-FADS1 rs174547 SNP interaction in young Canadian adults. Prostaglandins, leukotrienes, and essential fatty acids, 180, 102439. https://doi.org/10.1016/j.plefa.2022.102439. PMID: 35500529. DOI: 10.1016/j.plefa.2022.102439

Perceived challenges and strategies to achieve Canada’s Food Guide recommendation to “Cook more often”: Findings from parents of young children. Laila, A., Leme, A. C., Hou, S., Ma, D. W. L., & Haines, J. (2023). Perceived challenges and strategies to achieve Canada’s Food Guide recommendation to “Cook more often”: Findings from parents of young children. Appetite, 182, 106413. https://doi.org/10.1016/j.appet.2022.106413. PMID: 36529319. DOI: 10.1016/j.appet.2022.106413

The degree of food processing is associated with anthropometric measures of obesity in Canadian families with preschool-aged children. Ashraf, R., Duncan, A. M., Darlington, G., Buchholz, A. C., Haines, J., & Ma, D. W. L. (2022). The degree of food processing is associated with anthropometric measures of obesity in Canadian families with preschool-aged children. Frontiers in nutrition, 9, 1005227. https://doi.org/10.3389/fnut.2022.1005227. PMID: 36211496. PMCID: PMC9537364.
DOI: 10.3389/fnut.2022.1005227

Differential Effects of Short-Chain Fatty Acids on L6 Myotube Inflammatory Mediator Production in Response to Lipopolysaccharide- or Palmitic Acid-Stimulation. Martin, J. L. A., Cartwright, N. M., Hutchinson, A. L., Robinson, L. E., Ma, D. W. L., & Monk, J. M. (2022). Differential Effects of Short-Chain Fatty Acids on L6 Myotube Inflammatory Mediator Production in Response to Lipopolysaccharide- or Palmitic Acid-Stimulation. Nutrients, 14(14), 2826. https://doi.org/10.3390/nu14142826. PMID: 35889783.
PMCID: PMC9320465. DOI: 10.3390/nu14142826

Bilayer Forming Phospholipids as Targets for Cancer Therapy. Stoica, C., Ferreira, A. K., Hannan, K., & Bakovic, M. (2022). Bilayer Forming Phospholipids as Targets for Cancer Therapy. International journal of molecular sciences, 23(9), 5266. https://doi.org/10.3390/ijms23095266. PMID: 35563655.
PMCID: PMC9100777. DOI: 10.3390/ijms23095266

Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation. St Germain, M., Iraji, R., & Bakovic, M. (2023). Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation. Frontiers in nutrition, 9, 1094273. https://doi.org/10.3389/fnut.2022.1094273. PMID: 36687696. PMCID: PMC9849821.
DOI: 10.3389/fnut.2022.1094273

Transcription factor CREB3 is a potent regulator of high-fat diet-induced obesity and energy metabolism. Smith, B. S., Diaguarachchige De Silva, K. H., Hashemi, A., Duncan, R. E., Grapentine, S., Bakovic, M., & Lu, R. (2022). Transcription factor CREB3 is a potent regulator of high-fat diet-induced obesity and energy metabolism. International journal of obesity (2005), 46(8), 1446–1455. https://doi.org/10.1038/s41366-022-01128-w. PMID: 35637262. DOI: 10.1038/s41366-022-01128-w

Pcyt2 deficiency causes age-dependant development of nonalcoholic steatohepatitis and insulin resistance that could be attenuated with phosphoethanolamine. Grapentine, S., Singh, R. K., Basu, P., Sivanesan, S., Mattos, G., Oresajo, O., Cheema, J., Demeke, W., Dolinsky, V. W., & Bakovic, M. (2022). Pcyt2 deficiency causes age-dependant development of nonalcoholic steatohepatitis and insulin resistance that could be attenuated with phosphoethanolamine. Scientific reports, 12(1), 1048. https://doi.org/10.1038/s41598-022-05140-y. PMID: 35058529. PMCID: PMC8776951.
DOI: 10.1038/s41598-022-05140-y

Dose-response relationship between dietary choline and serum lipid profile, energy expenditure, and respiratory quotient in overweight adult cats fed at maintenance energy requirements. Rankovic, A., Godfrey, H., Grant, C. E., Shoveller, A. K., Bakovic, M., Kirby, G., & Verbrugghe, A. (2022). Dose-response relationship between dietary choline and serum lipid profile, energy expenditure, and respiratory quotient in overweight adult cats fed at maintenance energy requirements. Journal of animal science, 100(7), skac202. https://doi.org/10.1093/jas/skac202. PMID: 35641141. PMCID: PMC9259596.
DOI: 10.1093/jas/skac202

Sex Differences in the Behavioural Outcomes of Prenatal Nicotine and Tobacco Exposure. Sikic, A., Frie, J. A., Khokhar, J. Y., & Murray, J. E. (2022). Sex Differences in the Behavioural Outcomes of Prenatal Nicotine and Tobacco Exposure. Frontiers in neuroscience, 16, 921429. https://doi.org/10.3389/fnins.2022.921429. PMID: 35873826. PMCID: PMC9304689. DOI: 10.3389/fnins.2022.921429

Addiction-Related Outcomes of Nicotine and Alcohol Co-use: New Insights Following the Rise in Vaping. Frie, J. A., Nolan, C. J., Murray, J. E., & Khokhar, J. Y. (2022). Addiction-Related Outcomes of Nicotine and Alcohol Co-use: New Insights Following the Rise in Vaping. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 24(8), 1141–1149. https://doi.org/10.1093/ntr/ntab23. PMID: 34758090. PMCID: PMC9278825. DOI: 10.1093/ntr/ntab231

Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet. Doucette, W. T., Smedley, E. B., Ruiz-Jaquez, M., Khokhar, J. Y., & Smith, K. S. (2022). Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet. Brain research, 1784, 147886. https://doi.org/10.1016/j.brainres.2022.147886. PMID: 35314149. PMCID: PMC9161366.
DOI: 10.1016/j.brainres.2022.147886

Rev-erb α Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice. Al-Sabagh, Y., Thorpe, H. H. A., Jenkins, B. W., Hamidullah, S., Talhat, M. A., Suggett, C. B., Reitz, C. J., Rasouli, M., Martino, T. A., & Khokhar, J. Y. (2022). Rev-erbα Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice. International journal of molecular sciences, 23(9), 5197. https://doi.org/10.3390/ijms23095197. PMID: 35563586.
PMCID: PMC9104180. DOI: 10.3390/ijms23095197

Intermittent cold exposure improves glucose homeostasis despite exacerbating diet-induced obesity in mice housed at thermoneutrality. McKie, G. L., Shamshoum, H., Hunt, K. L., Thorpe, H. H. A., Dibe, H. A., Khokhar, J. Y., Doucette, C. A., & Wright, D. C. (2022). Intermittent cold exposure improves glucose homeostasis despite exacerbating diet-induced obesity in mice housed at thermoneutrality. The Journal of physiology, 600(4), 829–845. https://doi.org/10.1113/JP281774. PMID: 34192813. DOI: 10.1113/JP281774

Alcohol and Vaporized Nicotine Co-exposure During Adolescence Contribute Differentially to Sex-Specific Behavioral Effects in Adulthood. Ruffolo, J., Frie, J. A., Thorpe, H. H. A., Talhat, M. A., & Khokhar, J. Y. (2022). Alcohol and Vaporized Nicotine Co-exposure During Adolescence Contribute Differentially to Sex-Specific Behavioral Effects in Adulthood. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 24(8), 1177–1185. https://doi.org/10.1093/ntr/ntab250. PMID: 34865152.
PMCID: PMC9278839. DOI: 10.1093/ntr/ntab250

Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells. Dufour, J., Sabry, R., Khokhar, J. Y., & Favetta, L. A. (2023). Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells. Toxicology in vitro : an international journal published in association with BIBRA, 88, 105549. https://doi.org/10.1016/j.tiv.2022.105549. PMID: 36596389. DOI: 10.1016/j.tiv.2022.105549

Clozapine Increases Nestin Concentration in the Adult Male Rat Hippocampus: A Preliminary Study. Kayir, H., Jenkins, B. W., Alural, B., & Khokhar, J. Y. (2022). Clozapine Increases Nestin Concentration in the Adult Male Rat Hippocampus: A Preliminary Study. International journal of molecular sciences, 23(7), 3436. https://doi.org/10.3390/ijms23073436. PMID: 35408792. PMCID: PMC8998718.
DOI: 10.3390/ijms23073436

Maternal immune activation and adolescent alcohol exposure increase alcohol drinking and disrupt cortical-striatal-hippocampal oscillations in adult offspring. Henricks, A. M., Sullivan, E. D. K., Dwiel, L. L., Li, J. Y., Wallin, D. J., Khokhar, J. Y., & Doucette, W. T. (2022). Maternal immune activation and adolescent alcohol exposure increase alcohol drinking and disrupt cortical-striatal-hippocampal oscillations in adult offspring. Translational psychiatry, 12(1), 288. https://doi.org/10.1038/s41398-022-02065-y. PMID: 35859084. PMCID: PMC9300672.
DOI: 10.1038/s41398-022-02065-y

Prevalence and characteristics of cannabis-induced toxicoses in pets: Results from a survey of veterinarians in North America. Amissah, R. Q., Vogt, N. A., Chen, C., Urban, K., & Khokhar, J. (2022). Prevalence and characteristics of cannabis-induced toxicoses in pets: Results from a survey of veterinarians in North America. PloS one, 17(4), e0261909. https://doi.org/10.1371/journal.pone.0261909. PMID: 35442991. PMCID: PMC9020701. DOI: 10.1371/journal.pone.0261909

Glutamine and GABA alterations in cingulate cortex may underlie alcohol drinking in a rat model of co-occurring alcohol use disorder and schizophrenia: an 1H-MRS study. McCunn, P., Chen, X., Gimi, B., Green, A. I., & Khokhar, J. Y. (2022). Glutamine and GABA alterations in cingulate cortex may underlie alcohol drinking in a rat model of co-occurring alcohol use disorder and schizophrenia: an 1H-MRS study. Schizophrenia (Heidelberg, Germany), 8(1), 67. https://doi.org/10.1038/s41537-022-00272-6. PMID: 35999232. PMCID: PMC9399110. DOI: 10.1038/s41537-022-00272-6

Cannabis Vapor Exposure Alters Neural Circuit Oscillatory Activity in a Neurodevelopmental Model of Schizophrenia: Exploring the Differential Impact of Cannabis Constituents. Jenkins, B. W., Buckhalter, S., Perreault, M. L., & Khokhar, J. Y. (2021). Cannabis Vapor Exposure Alters Neural Circuit Oscillatory Activity in a Neurodevelopmental Model of Schizophrenia: Exploring the Differential Impact of Cannabis Constituents. Schizophrenia bulletin open, 3(1), sgab052. https://doi.org/10.1093/schizbullopen/sgab052. PMID: 35036917. PMCID: PMC8752653. DOI: 10.1093/schizbullopen/sgab052

Genotyping of Chlamydia abortus using multiple loci variable number of tandem repeats analysis technique. Barati, S., Bakhtiari, N. M., Shokoohizadeh, L., Ghorbanpoor, M., & Momtaz, H. (2022). Genotyping of Chlamydia abortus using multiple loci variable number of tandem repeats analysis technique. BMC veterinary research, 18(1), 54. https://doi.org/10.1186/s12917-022-03142-6. PMID: 35073930. PMCID: PMC8785486. DOI: 10.1186/s12917-022-03142-6

An exploratory study on the presence of Helicobacter heilmannii and Helicobacter billis in the feces of companion dogs. Fatemi Khader, M., Pourmahdi Borujeni, M., Moori Bakhtiari, N., & Avizeh, R. (2022). An exploratory study on the presence of Helicobacter heilmannii and Helicobacter billis in the feces of companion dogs. Veterinary medicine and science, 8(2), 537–545. https://doi.org/10.1002/vms3.765. PMID: 35152551. PMCID: PMC8959293. DOI: 10.1002/vms3.765

2021

Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress.
Inna Rabinovich-Nikitin, Mina Rasouli, Cristine J Reitz, Illana Posen, Victoria Margulets, Rimpy Dhingra, Tarak N Khatua, James A Thliveris, Tami A Martino , Lorrie A Kirshenbaum. Autophagy. 2021 Nov;17(11):3794-3812. PMID: 34085589
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Circadian influence on inflammatory response during cardiovascular disease.
Iman S Aziz, Adam M McMahon, David Friedman, Inna Rabinovich-Nikitin, Lorrie A Kirshenbaum, Tami A Martino. Curr Opin Pharmacol. 2021 Apr;57:60-70. PMID: 33340915
– Print Publication

Blood flow restriction training and the high-performance athlete: science to application.
Christopher Pignanelli, Danny Christiansen, Jamie F Burr. J Appl Physiol (1985). 2021 Apr 1;130(4):1163-1170. PMID: 33600282.
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Cannabis and Athletic Performance.
Jamie F Burr, Christian P Cheung, Andreas M Kasper, Scott H Gillham, Graeme L Close. Sports Med. 2021 Sep;51(Suppl 1):75-87. PMID: 34515970.
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Editorial: Blood Flow Restriction: Rehabilitation to Performance.
Stephen D Patterson, Jamie F Burr, Stuart Warmington. Front Physiol. 2021 Apr 30;12:566421. PMID: 33995115.
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Sink or swim: innovations in aquatic health.
Lee Hill, Margo Mountjoy, James Miller, Jamie Burr. J Sports Med Phys Fitness. 2021 Aug;61(8):1104-1114. PMID: 34137575.
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Ischemic Preconditioning: Modulating Pain Sensitivity and Exercise Performance.
Joshua T Slysz, Jamie F Burr. Front Physiol. 2021 Jun 22;12:696488. PMID: 34239452.
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Vascular Function Is Differentially Altered by Distance after Prolonged Running.
Trevor J King, Alexandra M Coates, Joshua C Tremblay, Joshua T Slysz, Heather L Petrick, Christopher Pignanelli, Philip J Millar, Jamie F Burr. Med Sci Sports Exerc. 2021 Mar 1;53(3):597-605. PMID: 32804900.
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Cardiac autonomic recovery following traditional and augmented remote ischemic preconditioning.
William N Morley, Alexandra M Coates, Jamie F Burr. Eur J Appl Physiol. 2021 Jan;121(1):265-277. PMID: 33047259.
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Blood Flow Restriction Combined with Electrical Stimulation Attenuates Thigh Muscle Disuse Atrophy.
Joshua T Slysz, Matthew Boston, Robert King, Christopher Pignanelli, Geoffrey A Power, Jamie F Burr. Med Sci Sports Exerc. 2021 May 1;53(5):1033-1040. PMID: 33105390.
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Exercise alters cardiac function independent of acute systemic inflammation in healthy men.
Alexandra M Coates, Heather L Petrick, Philip J Millar, Jamie F Burr. Am J Physiol Heart Circ Physiol. 2021 May 1;320(5):H1762-H1773. PMID: 33710926.
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Examining the relationship between arterial stiffness and swim-training volume in elite aquatic athletes.
Christian P Cheung, Alexandra M Coates, Katharine D Currie, Trevor J King, Margo L Mountjoy, Jamie F Burr. Eur J Appl Physiol. 2021 Sep;121(9):2635-2645. PMID: 34132871.
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Examining the Relationship between Exercise Dependence, Disordered Eating, and Low Energy Availability.
Megan A Kuikman, Margo Mountjoy, Jamie F Burr. Nutrients. 2021 Jul 28;13(8):2601. PMID: 34444761.
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Moderate Load Resisted Sprints Do Not Improve Subsequent Sprint Performance in Varsity-Level Sprinters.
Kyle M A Thompson, Alanna K Whinton, Shane Ferth, Lawrence L Spriet, Jamie F Burr. J Strength Cond Res. 2021 Jan 1;35(1):72-77. PMID: 29570579.
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Endurance and Sprint Training Improve Glycemia and V?O2peak but only Frequent Endurance Benefits Blood Pressure and Lipidemia.
Heather L Petrick, Trevor J King, Christopher Pignanelli, Tara E Vanderlinde, Jeremy N Cohen, Graham P Holloway, Jamie F Burr. Med Sci Sports Exerc. 2021 Jun 1;53(6):1194-1205. PMID: 33315809.
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Habitual cannabis use is associated with altered cardiac mechanics and arterial stiffness, but not endothelial function in young healthy smokers.
Christian P Cheung, Alexandra M Coates, Philip J Millar, Jamie F Burr. J Appl Physiol (1985). 2021 Mar 1;130(3):660-670. PMID: 33444123.
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Blood flow restriction in the presence or absence of muscle contractions does not preserve vasculature structure and function following 14-days of limb immobilization.
Jeremy N Cohen, Joshua T Slysz, Trevor J King, Alexandra M Coates, Robert T King, Jamie F Burr. Eur J Appl Physiol. 2021 Sep;121(9):2437-2447. PMID: 34002326.
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The Dendrite Arbor of Purkinje Cells Is Altered Following to Tail Regeneration in the Leopard Gecko.
Stefanie S Bradley, Erika Howe, Craig D C Bailey, Matthew K Vickaryous. Integr Comp Biol. 2021 Sep 8;61(2):370-384. PMID: 34038505.
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Cranial ornamentation in the Late Cretaceous nodosaurid ankylosaur Hungarosaurus.
Attila Osi, Janos Magyar, Karoly Rosta, Matthew Vickaryous. PeerJ. 2021 Mar 3;9:e11010. PMID: 33717709.
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Lizard osteoderms – Morphological characterisation, biomimetic design and manufacturing based on three species.
Ce Liang, Arsalan Marghoub, Loic Kever, Sergio Bertazzo, Arkhat Abzhanov, Matthew Vickaryous, Anthony Herrel, Susan E Evans, Mehran Moazen. Bioinspir Biomim. 2021 Oct 25;16(6). PMID: 34525458.
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Future Tail Tales: A Forward-Looking, Integrative Perspective on Tail Research.
M J Schwaner, S T Hsieh, I Braasch, S Bradley, C B Campos, C E Collins, C M Donatelli, F E Fish, O E Fitch, B E Flammang, B E Jackson, A Jusufi, P J Mekdara, A Patel, B J Swalla, M Vickaryous, C P McGowan. Integr Comp Biol. 2021 Sep 8;61(2):521-537. PMID: 33999184.
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Cutaneous tactile sensitivity before and after tail loss and regeneration in the leopard gecko ( Eublepharis macularius)
Stefanie S Bradley, Erika Howe, Leah R Bent, Matthew K Vickaryous. J Exp Biol. 2021 Mar 1;224(Pt 5):jeb234054. PMID: 33526555.
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Characteristics and outcomes of cats with and without pacemaker placement for high-grade atrioventricular block.
M E Colpitts, S Fonfara, G Monteith, A R Pires, A Wong, S Raheb, M Lynne O’Sullivan. J Vet Cardiol. 2021 Apr;34:37-47. PMID: 33548737.
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ShcA expression in podocytes is dispensable for glomerular development but its upregulation is associated with kidney disease.
Claire E Martin, Nina Jones. Am J Transl Res. 2021 Aug 15;13(8):9874-9882. PMID: 34540124.
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Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma Multiforme.
Manali Tilak, Jennifer Holborn, Laura A New, Jasmin Lalonde, Nina Jones. Int J Mol Sci. 2021 Feb 12;22(4):1831. PMID: 33673213.
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Lower sympathetic transduction of blood pressure in uncontrolled hypertensives: physiological adaptation, methodological limitation, or both?
Massimo Nardone, Philip J Millar. J Hum Hypertens. 2021 Nov 18. PMID: 34795392.
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Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow.
Massimo Nardone, Carlin Katerberg, Anthony V Incognito, Andre L Teixeira, Lauro C Vianna, Philip J Millar. Am J Physiol Heart Circ Physiol. 2021 Oct 1;321(4):H798-H806. PMID: 34506224.
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Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise.
Jordan B Lee, Karambir Notay, Jeremy D Seed, Massimo Nardone, Lucas J Omazic, Philip J Millar. Med Sci Sports Exerc. 2021 Dec 1;53(12):2596-2604. PMID: 34310499.
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Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?
Massimo Nardone, Anthony V Incognito, Muhammad M Kathia, Lucas J Omazic, Jordan B Lee, Andre L Teixeira, Shengkun Xie, Lauro C Vianna, Philip J Millar. Am J Physiol Regul Integr Comp Physiol. 2021 Sep 1;321(3):R484-R494. PMID: 34287075.
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Postprandial superior mesenteric artery blood flow is related to changes in peripheral pulse wave harmonics and heart rate: implications for wearable technology?
Eamon Abdullah, Jordan B Lee, Karambir Notay, Philip J Millar. J Appl Physiol (1985). 2021 Aug 1;131(2):681-688. PMID: 34264128.
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Muscle sympathetic single-unit responses during rhythmic handgrip exercise and isocapnic hypoxia in males: the role of sympathoexcitation magnitude.
Anthony V Incognito, Andre L Teixeira, Brooke M Shafer, Massimo Nardone, Tyler D Vermeulen, Glen E Foster, Philip J Millar. Neurophysiol. 2021 Jul 1;126(1):170-180. PMID: 34133241.
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Blood Pressure Responses to Static and Dynamic Knee Extensor Exercise between Sexes: Role of Absolute Contraction Intensity.
Jordan B Lee, William Lutz, Lucas J Omazic, Mitchell A Jordan, Joseph Cacoilo, Matthew Garland, Geoffrey A Power, Philip J Millar. Med Sci Sports Exerc. 2021 Sep 1;53(9):1958-1968. PMID: 33756524.
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Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury.
Jordan W Squair, Matthieu Gautier, Lois Mahe, Jan Elaine Soriano, Andreas Rowald, Arnaud Bichat, Newton Cho, Mark A Anderson, Nicholas D James, Jerome Gandar, Anthony V Incognito, Giuseppe Schiavone, Zoe K Sarafis, Achilleas Laskaratos, Kay Bartholdi, Robin Demesmaeker, Salif Komi, Charlotte Moerman, Bita Vaseghi, Berkeley Scott, Ryan Rosentreter, Claudia Kathe, Jimmy Ravier, Laura McCracken, Xiaoyang Kang, Nicolas Vachicouras, Florian Fallegger, Ileana Jelescu, YunLong Cheng, Qin Li, Rik Buschman, Nicolas Buse, Tim Denison, Sean Dukelow, Rebecca Charbonneau, Ian Rigby, Steven K Boyd, Philip J Millar, Eduardo Martin Moraud, Marco Capogrosso, Fabien B Wagner, Quentin Barraud, Erwan Bezard, Stephanie P Lacour, Jocelyne Bloch, Gregoire Courtine, Aaron A Phillips. Nature. 2021 Feb;590(7845):308-314. PMID: 33505019.
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Remote ischemic conditioning for acute respiratory distress syndrome in COVID-19.
Anthony V Incognito, Philip J Millar, W Glen Pyle. Am J Physiol Lung Cell Mol Physiol. 2021 Mar 1;320(3):L331-L338. PMID: 33404365.
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Do skeletal muscle motor units and microvascular units align to help match blood flow to metabolic demand?
Coral L Murrant, Nicole M Fletcher, Eamon J H Fitzpatrick, Kinley S Gee. Eur J Appl Physiol. 2021 May;121(5):1241-1254. PMID: 33538852.
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Capillaries communicate with the arteriolar microvascular network by a pannexin/purinergic-dependent pathway in hamster skeletal muscle.
Iain R Lamb, Nicole M Novielli-Kuntz, Coral L Murrant. Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1699-H1711. PMID: 33606585.
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Cold acclimation induces life stage-specific responses in the cardiac proteome of western painted turtles (Chrysemys picta bellii): implications for anoxia tolerance.
Sarah L Alderman, Claire L Riggs, Oliver M N Bullingham, Todd E Gillis, Daniel E Warren. J Exp Biol. 2021 Jul 15;224(14):jeb242387. PMID: 34328184.
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Pharmacokinetics and bioavailability of ketoprofen when compounded with iron dextran for use in nursing piglets.
Kristen J Reynolds, Ron Johnson, Robert M Friendship, Jennifer Brown, Saad Enouri, Ronette Gehring, Terri L O’Sullivan. Can Vet J. 2021 Nov;62(11):1211-1218. PMID: 34728849.
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Pharmacokinetics and pharmacodynamics of doxycycline in a Streptococcusequi subsp. zooepidemicus infection model in horses.
Ronan J J Chapuis, Joe S Smith, Fabienne D Uehlinger, Melissa Meachem, Ron Johnson, Patricia M Dowling. J Vet Pharmacol Ther. 2021 Sep;44(5):766-775. PMID: 34057219.
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Feline hypertrophic cardiomyopathy: reduced microvascular density and involvement of CD34+ interstitial cells.
Josep M Monne Rodriguez, Sonja Fonfara, Udo Hetzel, Anja Kipar. Vet Pathol. 2021 Dec 27:3009858211062631. PMID: 34955067.
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Association of myocardial parasitic load with cardiac biomarkers and other selected variables in 10 dogs with advanced Canine Leishmaniasis.
Domingo Casamian-Sorrosal, Rafael Barrera-Chacon, Sonja Fonfara, Silvia Belinchon-Lorenzo, Luis Gomez-Gordo, Javier Galapero-Arroyo, Javier Fernandez-Cotrina, Jose Ignacio Cristobal-Verdejo, Francisco Javier Duque. Vet Rec. 2021 Sep;189(6):e198. PMID: 33899945.
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Myocardial transcription of inflammatory and remodeling markers in cats with hypertrophic cardiomyopathy and systemic diseases associated with an inflammatory phenotype.
Sonja Fonfara, Sarah Kitz, Gabrielle Monteith, Shelley Hahn, Anja Kipar. Res Vet Sci. 2021 May;136:484-494. PMID: 33848803.
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2020

Circadian Mutant Mice with Obesity and Metabolic Syndrome are Resilient to Cardiovascular Disease.
Cristine J Reitz, Faisal J Alibhai , Bruna Gazzi de Lima Seolin, Ashley Susan Nemec-Bakk, Neelam Khaper, Tami A Martino. Am J Physiol Heart Circ Physiol. 2020 Sep 28. PMID: 32986958
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Circadian influence on the microbiome improves heart failure outcomes.
Priya Mistry, Cristine J Reitz, Tarak Nath Khatua, Mina Rasouli, Kaitlyn Oliphant, Martin E Young, Emma Allen-Vercoe, Tami A Martino. J Mol Cell Cardiol. 2020 Sep 19;149:54-72. PMID: 32961201
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Differential effects of REV-ERBa/b agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption.
Sobuj Mia, Mariame S Kane , Mary N Latimer , Cristine J Reitz , Ravi Sonkar, Gloria A Benavides, Samuel R Smith, Stuart J Frank , Tami A Martino , Jianhua Zhang , Victor M Darley-Usmar , Martin E Young. Am J Physiol Heart Circ Physiol. 2020 Jun 1PMID: 32357113
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The Time for Circadian Medicine.
Tami A Martino, Mary E Harrington. J Biol Rhythms. 2020 Oct;35(5):419-420. PMID: 32746705
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Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study.
Adrian Boswood, Sonya G Gordon, Jens Haggstrom, Martin Vanselow, Gerhard Wess, Rebecca L Stepien, Mark A Oyama, Bruce W Keene, John Bonagura, Kristin A MacDonald, Mark Patteson , Sarah Smith , Philip R Fox, Karen Sanderson, Richard Woolley , Viktor Szatmari , Pierre Menaut , Whitney M Church , M Lynne OSullivan , Jean-Philippe Jaudon , Jan-Gerd Kresken, John Rush , Kirstie A Barrett , Steven L Rosenthal , Ashley B Saunders , Ingrid Ljungvall , Michael Deinert, Eric Bomassi, Amara H Estrada, Maria J Fernandez Del Palacio, N Sydney Moise , Jonathan A Abbott, Yoko Fujii, Alan Spier , Michael W Luethy , Roberto A Santilli , Masami Uechi, Anna Tidholm , Christoph Schummer, Philip Watson J Vet Intern Med. 2020 May PMID: 32200574
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Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases.
Kendal Prill, John F Dawson. Int J Mol Sci. 2020 Jan 15;21(2):542. PMID: 31952119
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The Dark Side of Actin: Cardiac actin variants highlight the role of allostery in disease development.
Grace Zi Teng, John F Dawson. Arch Biochem Biophys. 2020 Oct 10;695:108624.PMID: 33049292
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An examination of individual responses to ischemic preconditioning and the effect of repeated ischemic preconditioning on cycling performance.
J T Slysz, H L Petrick, J P Marrow, J F Burr. Eur J Sport Sci. 2020 Jun;20(5):633-640. PMID: 31429381
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Low-load resistance training to task failure with and without blood flow restriction: muscular functional and structural adaptations.
Christopher Pignanelli, Heather L Petrick, Fatemeh Keyvani, George J F Heigenhauser, Joe Quadrilatero, Graham P Holloway, Jamie F Burr. Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R284-R295. PMID: 31823670
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Impairment of Thermoregulation and Performance via Mild Dehydration in Ice Hockey Goaltenders.
CDevin G McCarthy, Kate A Wickham, Tyler F Vermeulen, Danielle L Nyman, Shane Ferth, Jamie M Pereira, Dennis J Larson, Jamie F Burr, Lawrence L Spriet. Int J Sports Physiol Perform. 2020 Feb 25;15(6):833-840. PMID: 32101792
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In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle.
Heather L Petrick, Henver S Brunetta, Chris Pignanelli, Everson A Nunes, Luc J C van Loon, Jamie F Burr, Graham P Holloway. J Physiol. 2020 Jul 31. doi: 10.1113/JP280032. PMID: 32735362
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Vascular Function Is Differentially Altered by Distance following Prolonged Running.
Trevor J King, Alexandra M Coates, Joshua C Tremblay, Joshua T Slysz, Heather L Petrick, Christopher Pignanelli, Philip J Millar, Jamie F Burr. Med Sci Sports Exerc. 2020 Aug 15. PMID: 32804900
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Repeated Application of a Novel Creatine Cream Improves Muscular Peak and Average Power in Male Subjects.
Alanna K Whinton, Katelynn Donahoe, Ruirui Gao, Kyle M A Thompson, Rachel Aubry, Travis J Saunders, Adam Johnston, Philip D Chilibeck, Jamie F Burr. J Strength Cond Res. 2020 Sep;34(9):2482-2491. PMID: 32865944
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In Response to: Risk of Muscle Damage With Blood Flow-Restricted Exercise Should Not Be Overlooked.
Kyle M A Thompson, Jamie F Burr. Clin J Sport Med. 2020 Sep 15. PMID: 32941382
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The Effect of a Stretch-Shortening Cycle on Muscle Activation and Muscle Oxygen Consumption: A Study of History-Dependenc.
Kevin E Caron, Jamie F Burr, Geoffrey A Power. J Strength Cond Res. 2020 Sep 16. PMID: 32947570
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Cardiac autonomic recovery following traditional and augmented remote ischemic preconditioning.
William N Morley, Alexandra M Coates, Jamie F Burr. Eur J Appl Physiol. 2020 Oct 13.
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Alterations in Cardiac Function Following Endurance Exercise Are Not Duration Dependent.
Alexandra M Coates, Trevor J King, Katharine D Currie, Joshua C Tremblay, Heather L Petrick, Joshua T Slysz, Christopher Pignanelli, Jordan A Berard, Philip J Millar, Jamie F Burr. Front Physiol. 2020 Sep 18 PMID: 33071833.
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Blood Flow Restriction Combined with Electrical Stimulation Attenuates Thigh Muscle Disuse Atrophy.
Joshua T Slysz, Matthew Boston, Robert King, Christopher Pignanelli, Geoffrey A Power, Jamie F Burr. Med Sci Sports Exerc. 2020 Oct 22.
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Off-Ice Resisted Sprints Best Predict All-Out Skating Performance in Varsity Hockey Players.
Kyle M A Thompson, Abdul Safadie, Josh Ford, Jamie F Burr. J Strength Cond Res. 2020 Oct 30.
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Response: Commentary: Can Blood Flow Restricted Exercise Cause Muscle Damage? Commentary on Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety.
Jamie F Burr, Luke Hughes, Stuart Warmington, Brendan R Scott, Johnny Owens, Takashi Abe, Jakob L Nielsen, Cleiton Augusto Libardi, Gilberto Laurentino, Gabriel Rodrigues Neto, Christopher Brandner, Juan Martin-Hernandez, Jeremy Loenneke, Stephen D Patterson. Front Physiol. 2020 Oct 30;11:574633.
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Multivalent nephrin-Nck interactions define a threshold for clustering and tyrosine-dependent nephrin endocytosis.
Claire E Martin, Laura A New, Noah J Phippen, Ava Keyvani Chahi, Alexander E Mitro, Tomoko Takano, Tony Pawson, Ivan M Blasutig, Nina Jones. J Cell Sci. 2020 Feb 24 PMID: 31974115.
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Sympathetic neural modulation of arterial stiffness in humans.
Massimo Nardone, John S Floras, Philip J Millar. Am J Physiol Heart Circ Physiol. 2020 Oct 9 PMID: 33035441.
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Sympathetic arterial baroreflex hysteresis in humans: different patterns during low- and high-pressure levels.
Anthony V Incognito , Milena Samora, Andrew D Shepherd, Roberta A Cartafina , Gabriel M N Guimaraes , Mauricio Daher , Lauro C Vianna , Philip J Millar. Am J Physiol Heart Circ Physiol. 2020 Oct 1 PMID: 32857604.
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Influence of Sex and Age on Muscle Sympathetic Nerve Activity of Healthy Normotensive Adults.
Daniel A Keir, Mark B Badrov, George Tomlinson, Catherine F Notarius, Derek S Kimmerly, Philip J Millar, J Kevin Shoemaker, John S Floras Hypertension. 2020 Sep. PMID: 32783757.
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Case Studies in Physiology: Sympathetic neural discharge patterns in a healthy young male during end-expiratory breath hold-induced sinus pause.
Tyler D Vermeulen, Brooke M Shafer, Anthony V Incognito, Massimo Nardone, Andre L Teixeira, Philip J Millar, J Kevin Shoemaker, Glen E Foster. J Appl Physiol (1985). 2020 Aug 1. PMID: 32644911.
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Within-breath sympathetic baroreflex sensitivity is modulated by lung volume but unaffected by acute intermittent hypercapnic hypoxia in men.
Massimo Nardone, Andre L Teixeira, Anthony V Incognito, Tyler D Vermeulen, Brooke M Shafer, Philip J Millar, Glen E Foster. Am J Physiol Heart Circ Physiol. 2020 Jul 1. PMID: 32502372.
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Looking beyond the mean: Are racial differences in beat-to-beat blood pressure variability among young men a harbinger for future cardiovascular risk?
Philip J Millar. Exp Physiol. 2020 Jul PMID: 32428314.
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New insights into the complexity of arterial baroreflex control of muscle sympathetic outflow in humans.
Anthony V Incognito, Philip J Millar. J Physiol 2020 May PMID: 32246770.
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Muscle sympathetic single-unit response patterns during progressive muscle metaboreflex activation in young healthy adults.
Anthony V Incognito, Massimo Nardone, Andr� L Teixeira, Jordan B Lee, Muhammad M Kathia, Philip J Millar J Neurophysiol . 2020 Sep 1;124(3):682-690. PMID: 32727266.
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2019

SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome.
Cristine J Reitz , Faisal J Alibhai , Tarak N Khatua , Mina Rasouli , Byram W Bridle , Thomas P Burris, Tami A Martino, Commun Biol. 2019 Oct 3;2:353. PMID: 31602405
– Print Publication

Circadian-Regulated Cell Death in Cardiovascular Diseases.
Inna Rabinovich-Nikitin , Brooke Lieberman , Tami A Martino , Lorrie A Kirshenbaum, Circulation. 2019 Feb 12;139(7):965-980.PMID: 30742538
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The Clock Mechanism Influences Neurobiology and Adaptations to Heart Failure in Clock 19/19 Mice With Implications for Circadian Medicine.
Austin T H Duong , Cristine J Reitz , Emma L Louth , Samantha D Creighton, Mina Rasouli , Ashley Zwaiman , Jeffrey T Kroetsch , Steffen-Sebastian Bolz , Boyer D Winters , Craig D C Bailey , Tami A Martino, Sci Rep. 2019 Mar 21;9(1):4994. PMID: 30899044
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A crosslinked and ribosylated actin trimer does not interact productively with myosin.
Navneet Sidhu, John F Dawson. Biochem Cell Biol. 2019 Apr;97(2):140-147. PMID: 30193076
– Print Publication

M-class hypertrophic cardiomyopathy cardiac actin mutations increase calcium sensitivity of regulated thin filaments.
Grace Zi Teng, Zeeshan Shaikh, Haidun Liu, John F Dawson. Biochem Biophys Res Commun. 2019 Oct 29;519(1):148-152. PMID: 31481237
– Print Publication

Impact of 8 weeks of repeated ischemic preconditioning on running performance.
Joshua T Slysz, Jamie F Burr. Eur J Appl Physiol. 2019 Jun;119(6):1431-1437. PMID: 30953176
– Print Publication

Ischemic Preconditioning: Improved Cycling Performance Despite Nocebo Expectation.
Christian P Cheung, Joshua T Slysz, Jamie F Burr. Int J Sports Physiol Perform. 2019 Oct 11;1-7. PMID: 31188700
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Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H 2 O 2 emission rates in human skeletal muscle.
Heather L Petrick, Christopher Pignanelli, Pierre-Andre Barbeau, Tyler A Churchward-Venne, Kaitlyn M J H Dennis, Luc J C van Loon, Jamie F Burr, Gijs H Goossens, Graham P Holloway. J Physiol. 2019 Aug;597(15):3985-3997. PMID: 31194254
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Effects of dynamic arm and leg exercise on muscle sympathetic nerve activity and vascular conductance in the inactive leg.
Connor J Doherty, Trevor J King, Anthony V Incognito, Jordan B Lee, Andrew D Shepherd, Joseph A Cacoilo, Joshua T Slysz, Jamie F Burr, Philip J Millar. J Appl Physiol (1985). 2019 Aug 1;127(2):464-472. PMID: 31246555
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The relationship of high-intensity cross-training with arterial stiffness.
Jamie F Burr, Jenny L Beck, John J Duroche. J Sport Health Sci. 2019 Jul;8(4):370-375. PMID: 31333891
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Localization of phosphotyrosine adaptor protein ShcD/SHC4 in the adult rat central nervous system.
Hannah N Robeson, Hayley R Lau, Laura A New , Jasmin Lalonde, John N Armstrong, Nina Jones. BMC Neurosci. 2019 Dec 10 PMID: 31823725
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2018

Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology.
Khaper N, Bailey CDC, Ghugre NR, Reitz C, Awosanmi Z, Waines R, Martino TA. Free Radic Biol Med. 2018:1;119:85-92. PMID: 29146117
– Print Publication

Constitutive cardiomyocyte proliferation in the leopard gecko (Eublepharis macularius).
Jacyniak K, Vickaryous MK. J Morphol. 2018 Sep;279(9):1355-1367.PMID: 30221788
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PI3Ka-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.
Patel VB, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, McLean BA, Basu R, Zhang P, Shah S, Dawson JF, Pyle WG, Hazra M, Kassiri Z, Hazra S, Vanhaesebroeck B, McCulloch CA, Oudit GY. Nat Commun. 2018;9(1):5390. PMID: 30568254
– Print Publication

Analytical validation of cardiac troponin I assays in horses.
Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW. J Vet Diagn Invest. 2018;(2):226-232. PMID: 29224512
– Print Publication

A crosslinked and ribosylated actin trimer does not interact productively with myosin.
Sidhu N, Dawson JF. Biochem Cell Biol. 2018. PMID: 30193076
– Print Publication

Identification of the actc1c cardiac actin gene in zebrafish.
Ojehomon M, Alderman SL, Sandhu L, Sutcliffe S, Van Raay T, Gillis TE, Dawson JF. Prog Biophys Mol Biol. 2018;138:32-37. PMID: 29913180
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Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy.
Despond EA, Dawson JF. Front Physiol. 2018;9:405. PMID: 29719515
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How the expression of green fluorescent protein and human cardiac actin in the heart influences cardiac function and aerobic performance in zebrafish Danio rerio.
Avey SR, Ojehomon M, Dawson JF, Gillis TE. J Fish Biol. 2018;92(1):177-189. PMID: 29194605
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Cardiac actin changes in the actomyosin interface have different effects on myosin duty ratio.
Liu H, Henein M, Anillo M, Dawson JF. Biochem Cell Biol. 2018;96(1):26-31. PMID: 28972856
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Characterization of a novel disease-associated mutation within NPHS1 and its effects on nephrin phosphorylation and signaling.
Cooper CJ, Dutta NT, Martin CE, Piscione TD, Thorner PS, Jones N. PLoS One. 2018;13(9):e0203905. PMID: 30212551
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Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation.
Smith TL, Van Slyke P, Jones N, Dumont DJ, McGlade CJ. Cell Signal. 2018 Nov;51:211-221. PMID: 30077653
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Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond.
Martin CE, Jones N. Front Endocrinol (Lausanne). 2018;9:302. PMID: 29922234
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Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors.
Kostas M, Haugsten EM, Zhen Y, Sorensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J. Mol Cell Proteomics. 2018;17(5):850-870. PMID: 29371290
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ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.
Martin CE, Petersen KA, Aoudjit L, Tilak M, Eremina V, Hardy WR, Quaggin SE, Takano T, Jones N. J Am Soc Nephrol. 2018;29(1):92-103. PMID: 29018139
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Left Ventricular Structure and Function in Elite Swimmers and Runners.
Currie KD, Coates AM, Slysz JT, Aubry RL, Whinton AK, Mountjoy ML, Millar PJ, Burr JF. Front Physiol. 2018;9:1700. PMID: 30546320
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Evidence for differential control of muscle sympathetic single units during mild sympathoexcitation in young healthy humans.
Incognito AV, Doherty CJ, Nardone M, Lee JB, Notay K, Seed JD, Millar PJ. Am J Physiol Heart Circ Physiol. 2018. PMID: 30388036
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Cardiovascular responses during isometric exercise following lengthening and shortening contractions.
Seed JD, St Peters B, Power GA, Millar PJ. J Appl Physiol (1985). 2018. PMID: 30382808
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TRPV1 and BDKRB2 receptor polymorphisms can influence the exercise pressor reflex.
Notay K, Klingel SL, Lee JB, Doherty CJ, Seed JD, Swiatczak M, Mutch DM, Millar PJ. J Physiol. 2018;596(21):5135-5148. PMID: 30206938
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Pharmacological assessment of the arterial baroreflex in a young healthy obese male with extremely low baseline muscle sympathetic nerve activity.
Incognito AV, Samora M, Cartafina RA, Guimaraes GMN, Daher M, Millar PJ, Vianna LC. Clin Auton Res. 2018;28(6):593-595. PMID: 30128682
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Blunted Cardiac Output from Overtraining Is Related to Increased Arterial Stiffness.
Coates AM, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018;50(12):2459-2464. PMID: 30102678
– Print Publication

Microneurographic characterization of sympathetic responses during 1-leg exercise in young and middle-aged humans.
Notarius CF, Millar PJ, Doherty CJ, Incognito AV, Haruki N, O’Donnell E, Floras JS. Appl Physiol Nutr Metab. 2018. PMID: 30063163
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Hypertensive Response With Exercise to Reveal Increased Cardiovascular Risk in Adults With Aortic Coarctation Repair: Value and Caution.
Millar PJ, Oechslin EN. Can J Cardiol. 2018;34(5):536-539. PMID: 29731016
– Print Publication

Heart Rate Variability Responses of Individuals With and Without Saline-Induced Obstructive Sleep Apnea.
Vena D, Bradley TD, Millar PJ, Floras JS, Rubianto J, Gavrilovic B, Perger E, Yadollahi A. J Clin Sleep Med. 2018;14(4):503-510. PMID: 29609720
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Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms.
Allwood MA, Edgett BA, Eadie AL, Huber JS, Romanova N, Millar PJ, Brunt KR, Simpson JA. J Physiol. 2018;596(15):3391-3410. PMID: 29604069
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Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.
Munoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H. J Hypertens. 2018;36(7):1477-1485. PMID: 29557905
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Comparison of laboratory and ambulatory measures of central blood pressure and pulse wave reflection: hitting the target or missing the mark?.
Burns MJ, Seed JD, Incognito AV, Doherty CJ, Notay K, Millar PJ. J Am Soc Hypertens. 2018;12(4):275-284. PMID: 29477564
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Evidence for Pressure-Independent Sympathetic Modulation of Central Pulse Wave Velocity.
Nardone M, Incognito AV, Millar PJ. J Am Heart Assoc. 2018;7(3). PMID: 29378730
– Print Publication

A comparison of static and dynamic cerebral autoregulation during mild whole-body cold stress in individuals with and without cervical spinal cord injury: a pilot study.
van der Scheer JW, Kamijo YI, Leicht CA, Millar PJ, Shibasaki M, Goosey-Tolfrey VL, Tajima F. Spinal Cord. 2018;56(5):469-477. PMID: 29330514
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Three Weeks of Overload Training Increases Resting Muscle Sympathetic Activity.
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018;50(5):928-937. PMID: 29206785
– Print Publication

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women.
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ. Med Sci Sports Exerc. 2018;50(4):778-784. PMID: 29135658
– Print Publication

Interindividual variability in muscle sympathetic responses to static handgrip in young men: evidence for sympathetic responder types?.
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Am J Physiol Regul Integr Comp Physiol. 2018;314(1):R114-R121. PMID: 29070505
– Print Publication

Muscle sympathetic nerve responses to passive and active one-legged cycling: insights into the contributions of central command.
Doherty CJ, Incognito AV, Notay K, Burns MJ, Slysz JT, Seed JD, Nardone M, Burr JF, Millar PJ. Am J Physiol Heart Circ Physiol. 2018;314(1):H3-H10. PMID: 28939650
– Print Publication

Enhanced Metabolic Stress Augments Ischemic Preconditioning for Exercise Performance.
Slysz JT, Burr JF. Front Physiol. 2018;9:1621. PMID: 30498458
– Print Publication

The Acute Metabolic and Vascular Impact of Interrupting Prolonged Sitting: A Systematic Review and Meta-Analysis.
Saunders TJ, Atkinson HF, Burr J, MacEwen B, Skeaff CM, Peddie MC. Sports Med. 2018;48(10):2347-2366. PMID: 30078066
– Print Publication

Testing a novel isokinetic dynamometer constructed using a 1080 Quantum.
Whinton AK, Thompson KMA, Power GA, Burr JF. PLoS One. 2018;13(7):e0201179. PMID: 30028864
– Print Publication

An Assessment of Running Power as a Training Metric for Elite and Recreational Runners.
Aubry RL, Power GA, Burr JF. J Strength Cond Res. 2018;32(8):2258-2264. PMID: 29912073
– Print Publication

Prevalence of Indicators of Low Energy Availability in Elite Female Sprinters.
Sygo J, Coates AM, Sesbreno E, Mountjoy ML, Burr JF. Int J Sport Nutr Exerc Metab. 2018;28(5):490-496. PMID: 29757049
– Print Publication

Investigating the use of pre-training measures of autonomic regulation for assessing functional overreaching in endurance athletes.
Coates AM, Hammond S, Burr JF. Eur J Sport Sci. 2018;18(7):965-974. PMID: 29635969
– Print Publication

Moderate Load Resisted Sprints do Not Improve Subsequent Sprint Performance in Varsity Level Sprinters.
Thompson KMA, Whinton AK, Ferth S, Spriet LL, Burr JF. J Strength Cond Res. 2018. PMID: 29570579
– Print Publication

Ischemic Preconditioning: No Influence on Maximal Sprint Acceleration Performance.
Thompson KMA, Whinton AK, Ferth S, Spriet LL, Burr JF. Int J Sports Physiol Perform. 2018;13(8):986-990. PMID: 29345532
– Print Publication

Risks of Exertional Rhabdomyolysis With Blood Flow-Restricted Training: Beyond the Case Report.
Thompson KMA, Slysz JT, Burr JF. Clin J Sport Med. 2018;28(6):491-492. PMID: 29084035
– Print Publication

The Effects of Blood Flow Restricted Electrostimulation on Strength and Hypertrophy.
Slysz JT, Burr JF. J Sport Rehabil. 2018;27(3):257-262. PMID: 28513326
– Print Publication

Clinicopathological features and comorbidities of cats with mild, moderate or severe hyperthyroidism: a radioiodine referral population.
Watson N, Murray JK, Fonfara S, Hibbert A. J Feline Med Surg. 2018 Dec;20(12):1130-1137. PMID: 29432704
– Print Publication

Splenic blood-flow response following myocardial infarction in rat.
Ruggiero SA, Huber JS, Murrant CL, Brunt KR, Simpson JA. Can J Physiol Pharmacol. 2018;96(11):1060-1068. PMID: 30102865
– Print Publication

Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct.
Platt MJ, Huber JS, Romanova N, Brunt KR, Simpson JA. Front Physiol. 2018;9:472. PMID: 29867532
– Print Publication

A Comparison and Calibration of a Wrist-Worn Blood Pressure Monitor for Patient Management: Assessing the Reliability of Innovative Blood Pressure Devices.
Melville S, Teskey R, Philip S, Simpson JA, Lutchmedial S, Brunt KR. J Med Internet Res. 2018;20(4):e111. PMID: 29695375
– Print Publication

Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats.
Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP. Am J Physiol Regul Integr Comp Physiol. 2018;315(2):R191-R204. PMID: 29513565
– Print Publication

Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain.
Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou YQ, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT. Am J Physiol Regul Integr Comp Physiol. 2018;314(4):R611-R622. PMID: 29351418
– Print Publication

Heritable Skeletal Disorders Arising from Defects in Processing and Transport of Type I Procollagen from the ER: Perspectives on Possible Therapeutic Approaches.
Cutrona MB, Morgan NE, Simpson JC. Handb Exp Pharmacol. 2018;245:191-225. PMID: 29071510
– Print Publication

Transforming growth factor-B1 induces differentiation of rainbow trout (Oncorhynchus mykiss) cardiac fibroblasts into myofibroblasts.
Johnston EF, Gillis TE. J Exp Biol. 2018;221(Pt 24). PMID: 30397172
– Print Publication

Developmental and latent effects of diluted bitumen exposure on early life stages of sockeye salmon (Oncorhynchus nerka).
Alderman SL, Lin F, Gillis TE, Farrell AP, Kennedy CJ. Aquat Toxicol. 2018 Sep;202:6-15. PMID: 29966910
– Print Publication

Cellular mechanisms of slime gland refilling in Pacific hagfish (Eptatretus stoutii).
Schorno S, Gillis TE, Fudge DS. J Exp Biol. 2018;221(Pt 16). PMID: 29941614
– Print Publication

Emptying and refilling of slime glands in Atlantic (Myxine glutinosa) and Pacific (Eptatretus stoutii) hagfishes.
Schorno S, Gillis TE, Fudge DS. J Exp Biol. 2018;221(Pt 7). PMID: 29487153
– Print Publication

Arteriolar and capillary responses to CO2 and H+ in hamster skeletal muscle microvasculature: Implications for active hyperemia.
Charter ME, Lamb IR, Murrant CL. Microcirculation. 2018;25(7):e12494. PMID: 30030943
– Print Publication

Capillary response to skeletal muscle contraction: evidence that redundancy between vasodilators is physiologically relevant during active hyperaemia.
Lamb IR, Novielli NM, Murrant CL. J Physiol. 2018;596(8):1357-1372. PMID: 29417589
– Print Publication

Marginal ancestral contributions to atrial fibrillation in the Standardbred racehorse: Comparison of cases and controls.
Kraus M, Physick-Sheard P, Brito LF, Sargolzaei M, Schenkel FS. PLoS One. 2018;13(5):e0197137. PMID: 29763439
– Print Publication

2017

Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Alibhai FJ, LaMarre J, Reitz CJ, Tsimakouridze EV, Kroetsch JT, Bolz SS, Shulman A, Steinberg S, Burris TP, Oudit GY, Martino TA. J Mol Cell Cardiol. 2017;105:24-37. PMID: 28223222
– Print Publication

Female Clockd19/d19 Mice are Protected from the Development of Age-Dependent Cardiomyopathy.
Alibhai FJ, Reitz CJ, Peppler WT, Basu P, Sheppard P, Choleris E, Bakovic M, Martino TA. Cardiovasc Res. 2017 Sep 12. [Epub ahead of print]. PMID: 28927226
– Print Publication

Guidelines for Genome-Scale Analysis of Biological Rhythms.
Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, et al. Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptacek LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB. J Biol Rhythms. 2017;32(5):380-393. PMID: 29098954
– Print Publication

Cardiac Clocks and Preclinical Translation.
Mistry P, Duong A, Kirshenbaum L, Martino TA. Heart Fail Clin. 2017;13(4):657-672. Review. PMID: 28865775
– Print Publication

Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology.
Khaper N, Bailey CDC, Ghugre NR, Reitz C, Awosanmi Z, Waines R, Martino TA. Free Radic Biol Med. 2017. pii: S0891-5849(17)31199-1. [Epub ahead of print] Review. PMID: 29146117
– Print Publication

Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart.
Feridooni HA, MacDonald JK, Ghimire A, Pyle WG, Howlett SE. Am J Physiol Heart Circ Physiol. 2017;312(1):H46-H59. PMID: 27793852
– Print Publication

Analytical validation of cardiac troponin I assays in horses.
Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW. J Vet Diagn Invest. 2017 Dec 1:1040638717747070. [Epub ahead of print] PMID: 29224512
– Print Publication

Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015).
Bascunan A, Thieman Mankin KM, Saunders AB, Bright JM, Scharf V, Singh A, O’Sullivan L, Brisson B, Estrada AH, Tou SP, Ruoff C. J Vet Cardiol. 2017;19(1):35-43. PMID: 27919727
– Print Publication

Development of a technique for determination of pulmonary artery pulse wave velocity in horses.
Silva GTA, Guest BB, Gomez DE, McGregor M, Viel L, O’Sullivan ML, Runciman J, Arroyo LG. J Appl Physiol (1985). 2017;122(5):1088-1094. PMID: 28183822
– Print Publication

Assessment of platelet function in healthy cats in response to commonly prescribed antiplatelet drugs using three point-of-care platelet function tests.
Ho KK, Abrams-Ogg AC, Wood RD, O’Sullivan ML, Kirby GM, Blois SL. J Feline Med Surg. 2017;19(6):638-647. PMID: 27170631
– Print Publication

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.
Boswood A, Gordon SG, Haggstrom J, Wess G, Stepien RL, Oyama MA, Keene BW, Bonagura J, MacDonald KA, Patteson M, Smith S, Fox PR, Sanderson K, Woolley R, Szatm�ri V, Menaut P, Church WM, O’Sullivan ML, Jaudon JP, Kresken JG, Rush J, Barrett KA, Rosenthal SL, Saunders AB, Ljungvall I, Deinert M, Bomassi E, Estrada AH, Fernandez Del Palacio MJ, Moise NS, Abbott JA, Fujii Y, Spier A, Luethy MW, Santilli RA, Uechi M, Tidholm A, Schummer C, Watson P. J Vet Intern Med. 2017 Dec 6. [Epub ahead of print] PMID: 29214723
– Print Publication

Cardiac actin changes in the actomyosin interface have different effects on myosin duty ratio.
Liu H, Henein ME, Anillo M, Dawson JF. Biochem Cell Biol. 2017 Oct 3. [Epub ahead of print] PMID: 28972856
– Print Publication

How the expression of green fluorescent protein and human cardiac actin in the heart influences cardiac function and aerobic performance in zebrafish Danio rerio.
Avey SR, Ojehomon M, Dawson JF, Gillis TE. J Fish Biol. 2017 Nov 30. [Epub ahead of print] PMID: 29194605

Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Wills MK, Keyvani Chahi A, Lau HR, Tilak M, Guild BD, New LA, Lu P, Jacquet K, Meakin SO, Bisson N, Jones N. J Biol Chem. 2017;292(14):5748-5759. PMID: 28213521
– Print Publication

The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking.
Wills MKB, Lau HR, Jones N. J Cell Sci. 2017;130(17):2808-2820. PMID: 28724758
– Print Publication

ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.
Martin CE, Petersen KA, Aoudjit L, Tilak M, Eremina V, Hardy WR, Quaggin SE, Takano T, Jones N. J Am Soc Nephrol. 2017 Oct 10. pii: ASN.2017030285. [Epub ahead of print] PMID: 29018139
– Print Publication

Ischemic preconditioning does not alter muscle sympathetic responses to static handgrip and metaboreflex activation in young healthy men.
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Physiol Rep. 2017;5(14). pii: e13342. PMID: 28720715
– Print Publication

Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study.
Notay K, Incognito AV, Millar PJ. Am J Physiol Heart Circ Physiol. 2017;313(1):H59-H65. PMID: 28476923
– Print Publication

Muscle sympathetic nerve responses to passive and active one-legged cycling: Insight into the contributions of central command.
Doherty CJ, Incognito AV, Notay K, Burns MJ, Slysz JT, Seed JD, Nardone M, Burr JF, Millar PJ. Am J Physiol Heart Circ Physiol. 2017 Sep 22:ajpheart.00494.2017. [Epub ahead of print] PMID: 28939650
– Print Publication

Inter-individual variability in muscle sympathetic responses to static handgrip in young men: Evidence for sympathetic responder types?
Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Am J Physiol Regul Integr Comp Physiol. 2017 Oct 25:ajpregu.00266.2017. [Epub ahead of print] PMID: 29070505
– Print Publication

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women.
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ. Med Sci Sports Exerc. 2017 Nov 10. [Epub ahead of print] PMID: 29135658
– Print Publication

Sex Differences in Cardiac Baroreflex Sensitivity following Isometric Handgrip Exercise.
Teixeira AL, Ritti-Dias R, Antonino D, Bottaro M, Millar PJ, Vianna LC. Med Sci Sports Exerc. 2017 Nov 13. [Epub ahead of print] PMID: 29135601
– Print Publication

Three Weeks of Overload Training Increases Resting Muscle Sympathetic Activity.
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF. Med Sci Sports Exerc. 2017 Dec 2. [Epub ahead of print] PMID: 29206785
– Print Publication

The Effects of Blood Flow Restricted Electrostimulation on Strength & Hypertrophy.
Slysz J, Burr JF. J Sport Rehabil. 2017:1-17. [Epub ahead of print] PMID: 28513326
-Print Publication

Incidence of Iron Deficiency and Iron Deficient Anemia in Elite Runners and Triathletes.
Coates A, Mountjoy M, Burr J. Clin J Sport Med. 2017;27(5):493-498. PMID: 27606953
– Print Publication

Risks of Exertional Rhabdomyolysis With Blood Flow-Restricted Training: Beyond the Case Report.
Thompson KMA, Slysz JT, Burr JF. Clin J Sport Med. 2017 Oct 26. [Epub ahead of print] PMID: 29084035
– Print Publication

UPEI-400, a conjugate of lipoic acid and scopoletin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Connell BJ, Saleh MC, Rajagopal D, Saleh TM. Food Chem Toxicol. 2017;100:175-182. PMID: 28017701
– Print Publication

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents.
Afifi TH, Okasha RM, Ahmed HEA, Ilas J, Saleh T, Abd-El-Aziz AS. EXCLI J. 2017;16:868-902. PMID: 28828001
– Print Publication

A novel synthetic chemical entity (UPEI-800) is neuroprotective in vitro and in an in vivo rat model of oxidative stress.
Saleh TM, Saleh MC, Connell BJ, Kucukkaya I, Abd-El-Aziz AS. Clin Exp Pharmacol Physiol. 2017;44(10):993-1000. PMID: 28504843
– Print Publication

A co-drug conjugate of naringenin and lipoic acid mediates neuroprotection in a rat model of oxidative stress.
Saleh TM, Saleh MC, Connell BJ, Song YH. Clin Exp Pharmacol Physiol. 2017;44(10):1008-1016. PMID: 28636787
– Print Publication

Myocardial leptin transcription in feline hypertrophic cardiomyopathy.
Fonfara S, Kitz S, Hetzel U, Kipar A. Res Vet Sci. 2017;112:105-108. PMID: 28213270
– Print Publication

Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.
Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA. Sci Transl Med. 2017;9(390). pii: eaag1303. PMID: 28515334
– Print Publication

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.
Yin JC, Platt MJ, Tian X, Wu X, Backx PH, Simpson JA, Araki T, Neel BG. Nat Commun. 2017;8:15518. PMID: 28548091
– Print Publication

Pulmonary Flow as an Improved Method for Determining Cardiac Output in Mice after Myocardial Infarction.
Platt MJ, Huber JS, Brunt KR, Simpson JA. J Am Soc Echocardiogr. 2017;30(6):612-623.e1. PMID: 28528655
– Print Publication

The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and Beta-cell mass.
Paglialunga S, Simnett G, Robson H, Hoang M, Pillai R, Arkell AM, Simpson JA, Bonen A, Huising M, Joseph JW, Holloway GP. Appl Physiol Nutr Metab. 2017;42(6):647-655. PMID: 28177704
– Print Publication

The Effect of Anthocyanin-Rich Purple Vegetable Diets on Metabolic Syndrome in Obese Zucker Rats.
Ayoub HM, McDonald MR, Sullivan JA, Tsao R, Platt M, Simpson J, Meckling KA. J Med Food. 2017;20(12):1240-1249. PMID: 28956702
– Print Publication

Temperature-induced cardiac remodelling in fish.
Keen AN, Klaiman JM, Shiels HA, Gillis TE. J Exp Biol. 2017;220(Pt 2):147-160. Review. PMID: 27852752
– Print Publication

Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance.
Alderman SL, Lin F, Farrell AP, Kennedy CJ, Gillis TE. Environ Toxicol Chem. 2017;36(2):354-360. PMID: 27328800
– Print Publication

Data for iTRAQ-based quantification of the cardiac proteome of rainbow trout (Oncorhynchus mykiss) at rest and with exercise training.
Dindia LA, Alderman SL, Gillis TE. Data Brief. 2017;13:32-36. PMID: 28560280
– Print Publication

Novel insights into cardiac remodelling revealed by proteomic analysis of the trout heart during exercise training.
Dindia LA, Alderman SL, Gillis TE. J Proteomics. 2017;161:38-46. PMID: 28365405
– Print Publication

Proteomic analysis of sockeye salmon serum as a tool for biomarker discovery and new insight into the sublethal toxicity of diluted bitumen.
Alderman SL, Dindia LA, Kennedy CJ, Farrell AP, Gillis TE. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:157-166. PMID: 28433920
– Print Publication

Transforming growth factor beta-1 (TGF-beta1) stimulates collagen synthesis in cultured rainbow trout cardiac fibroblasts.
Johnston EF, Gillis TE. J Exp Biol. 2017;220(Pt 14):2645-2653. PMID: 28495868
– Print Publication

Canadian Society for Exercise Physiology Symposium on Integrative Physiology Honouring Dr. Bengt Saltin: The use of Exercise to Study Integrative Physiology.
Murrant CL, MacDonald MJ. Appl Physiol Nutr Metab. 2017;42(1):99. PMID: 28055244
– Print Publication

Dose-dependent inhibition of uterine contractility by nitric oxide: A potential mechanism underlying persistent breeding-induced endometritis in the mare.
Khan FA, Chenier TS, Murrant CL, Foster RA, Hewson J, Scholtz EL. Theriogenology. 2017;90:59-64. PMID: 28166989
– Print Publication

Capillary endothelial cells as coordinators of skeletal muscle blood flow during active hyperemia.
Murrant CL, Lamb IR, Novielli NM. Microcirculation. 2017;24(3). Review. PMID: 28036147
– Print Publication

Associations of acute stress and overnight heart rate with feed efficiency in beef heifers.
Munro JC, Schenkel FS, Physick-Sheard PW, Fontoura AB, Miller SP, Tennessen T, Montanholi YR. Animal. 2017;11(3):452-460. PMID: 27514832
– Print Publication

Estimates of heritability of atrial fibrillation in the Standardbred racehorse.
Kraus M, Physick-Sheard PW, Brito LF, Schenkel FS. Equine Vet J. 2017;49(6):718-722. PMID: 28391631
– Print Publication

Perioperative analgesic use by Ontario veterinarians, 2012.
Reimann J, Dewey C, Bateman SW, Kerr C, Johnson R. Can Vet J. 2017;58(2):149-156. PMID: 28216684
– Print Publication

Pharmacokinetics of liposomal encapsulated buprenorphine suspension following subcutaneous administration to cats.
Johnson RJ, Kerr CL, Enouri SS, Modi P, Lascelles BDX, Del Castillo JRE. J Vet Pharmacol Ther. 2017;40(3):256-269. PMID: 27647259
– Print Publication

The Analysis of Phenylbutazone and Its Active Metabolite, Oxyphenbutazone, in Equine Tissues (Muscle, Kidney, and Liver), Urine, and Serum by LC-MS/MS.
Boison JO, Dowling P, Matus JL, Kinar J, Johnson R. J AOAC Int. 2017;100(4):1110-1122. PMID: 28145218
– Print Publication

2016

Day-Night Dependence of Gene Expression and Inflammatory Responses in the Remodeling Murine Heart post-Myocardial Infarction.
Bennardo M, Alibhai FJ, Tsimakouridze EV, Chinnappareddy N, Podobed P, Reitz CJ, Pyle WG, Simpson JA, Martino TA. Am J Physiol Regul Integr Comp Physiol. 2016:ajpregu.00200.2016. PMID: 27733386
– Print Publication

The neglected messengers: Control of cardiac myofilaments by protein phosphatases.
Lorenzen-Schmidt I, Clarke SB, Pyle WG. J Mol Cell Cardiol. 2016;101:81-89. PMID: 27721025
– Print Publication

Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015).
Bascunan A, Thieman Mankin KM, Saunders AB, Bright JM, Scharf V, Singh A, O’Sullivan L, Brisson B, Estrada AH, Tou SP, Ruoff C. J Vet Cardiol. 2016. pii: S1760-2734(16)30116-3. PMID: 27919727
– Print Publication

Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP.
Keyvani Chahi A, Martin CE, Jones N. J Biol Chem. 2016;291(24):12799-808. PMID: 27033705
– Print Publication

Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.
New LA, Martin CE, Scott RP, Platt MJ, Keyvani Chahi A, Stringer CD, Lu P, Samborska B, Eremina V, Takano T, Simpson JA, Quaggin SE, Jones N. J Am Soc Nephrol. 2016;27(8):2422-35. PMID: 26802179
– Print Publication

Cutaneous Mechanoreceptor Feedback from the Hand and Foot Can Modulate Muscle Sympathetic Nerve Activity.
Strzalkowski ND, Incognito AV, Bent LR, Millar PJ. Front Neurosci. 2016;10:568. eCollection 2016. PMID: 28008306
– Print Publication

Validity and reliability of measuring resting muscle sympathetic nerve activity using short sampling durations in healthy humans.
Notay K, Seed JD, Incognito AV, Doherty CJ, Nardone M, Burns MJ, Millar PJ. J Appl Physiol (1985). 2016;121(5):1065-1073. PMID: 27687563
– Print Publication

The Effects of Ischemic Preconditioning on Human Exercise Performance.
Incognito AV, Burr JF, Millar PJ. Sports Med. 2016;46(4):531-44. Review. PMID: 26645697
– Print Publication

Non-invasive electrocardiographic assessments of cardiac autonomic modulation in individuals with spinal cord injury.
Sharif H, Millar PJ, Incognito AV, Ditor DS. Spinal Cord. 2016;54(3):166-71. PMID: 26597693
– Print Publication

Incidence of Iron Deficiency and Iron Deficient Anemia in Elite Runners and Triathletes
Coates A, Mountjoy M, Burr J. Clin J Sport Med. 2016. PMID: 27606953
– Print Publication

The Acute Risks of Exercise in Apparently Healthy Adults and Relevance for Prevention of Cardiovascular Events.
Goodman JM, Burr JF, Banks L, Thomas SG. Can J Cardiol. 2016;32(4):523-32. Review. PMID: 27017149
– Print Publication

The efficacy of blood flow restricted exercise: A systematic review & meta-analysis.
Slysz J, Stultz J, Burr JF. Sci Med Sport. 2016;19(8):669-75. Review. PMID: 26463594
– Print Publication

UPEI-400, a conjugate of lipoic acid and scopoletin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Connell BJ, Saleh MC, Rajagopal D, Saleh TM. Food Chem Toxicol. 2016;100:175-182.[Epub ahead of print]. PMID: 28017701
– Print Publication

Usefulness of serum cardiac troponin I concentration as a marker of survival of harbor seal (Phoca vitulina) pups during rehabilitation.
Fonfara S, Sundermeyer J, Casamian Sorrosal D, Weber C, Rosenberger T. J Am Vet Med Assoc. 2016;249(12):1428-1435. PMID: 27901450
– Print Publication

“Fibroblast” pharmacotherapy – Advancing the next generation of therapeutics for clinical cardiology.
Eadie AL, Simpson JA, Brunt KR. J Mol Cell Cardiol. 2016;94:176-9. PMID: 27060557
– Print Publication

Dissecting the role of the myofilament in diaphragm dysfunction during the development of heart failure in mice.
Gillis TE, Klaiman JM, Foster A, Platt MJ, Huber JS, Corso MY, Simpson JA. Am J Physiol Heart Circ Physiol. 2016 Mar 1;310(5):H572-86. PMID: 26702144
– Print Publication

Temperature-induced cardiac remodeling in fish.
Keen AN, Klaiman JM, Shiels HA, Gillis TE. J Exp Biol. 2016. pii: jeb.128496. [Epub ahead of print] Review. PMID: 27852752
– Print Publication

A functional comparison of cardiac troponin C from representatives of three vertebrate taxa: Linking phylogeny and protein function.
Sears EJ, Gillis TE. Comp Biochem Physiol B Biochem Mol Biol. 2016;202:8-15. PMID: 27453566
– Print Publication

Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance.
Alderman SL, Lin F, Farrell AP, Kennedy CJ, Gillis TE. Environ Toxicol Chem. 2016. [Epub ahead of print]. PMID: 27328800
– Print Publication

Capillary endothelial cells as coordinators of skeletal muscle blood flow during active hyperaemia.
Murrant CL, Lamb IR, Novielli NM. Microcirculation. 2016. [Epub ahead of print]. PMID: 28036147
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Associations of acute stress and overnight heart rate with feed efficiency in beef heifers.
Munro JC, Schenkel FS, Physick-Sheard PW, Fontoura AB, Miller SP, Tennessen T, Montanholi YR. Animal. 2016 Aug 12:1-9. [Epub ahead of print]. PMID: 27514832
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Pharmacokinetics of liposomal encapsulated buprenorphine suspension following subcutaneous administration to cats.
Johnson RJ, Kerr CL, Enouri SS, Modi P, Lascelles BD, Del Castillo JR. J Vet Pharmacol Ther. 2016. [Epub ahead of print]. PMID: 27647259
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2015

Disruption of Circadian Rhythms and Sleep on Critical Illness and the Impact on Cardiovascular Events.
Reitz CJ, Martino TA. Curr Pharm Des. 2015;21(24):3505-11. PMID: 26144940
– Print Publication

Consequences of Circadian and Sleep Disturbances for the Cardiovascular System.
Alibhai FJ, Tsimakouridze EV, Reitz CJ, Pyle WG, Martino TA. Can J Cardiol. 2015;31(7):860-72. Epub 2015 Jan 26. PMID: 26031297
– Print Publication

Male-Specific Cardiac Dysfunction in CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)-Deficient Mice.
Basu P, Alibhai FJ, Tsimakouridze EV, Singh RK, Paglialunga S, Holloway GP, Martino TA, Bakovic M. Mol Cell Biol. 2015;35(15):2641-57. Epub 2015 May 18. PMID: 25986609
– Print Publication

Therapeutic applications of circadian rhythms for the cardiovascular system.
Tsimakouridze EV, Alibhai FJ, Martino TA. Front Pharmacol. 2015;6:77. eCollection 2015. PMID: 25941487
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Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology.
Martino TA, Young ME. J Biol Rhythms. 2015;30(3):183-205. Epub 2015 Mar 22. PMID: 25800587
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‘The Cardiac Clock’ in Circadian Clocks: Role in Health and Disease.
Alibhai FJ, Tsimakouridze EV, Reitz CJ, Pyle WG, Martino TA. Springer APS. 2015. In Press.

2-Deoxy-adenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy.
Cheng Y, Hogarth KA, O’Sullivan ML, Regnier M, Pyle WG. Am J Physiol Heart Circ Physiol. 2015:ajpheart.00530.2015. PMID: 26497964
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Do cardiac actin mutations lead to altered actomyosin interactions?
Dahari M, Dawson JF. Biochem Cell Biol. 2015;93(4):330-4. PMID: 26194323
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The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.
Bai F, Caster HM, Dawson JF, Kawai M. J Mol Cell Cardiol. 2015;79:123-32. PMID: 25451174
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Dissecting the role of the myofilament in diaphragm dysfunction during the development of heart failure in mice.
Gillis TE, Klaiman JM, Foster AJ, Platt MJ, Huber JS, Corso MY, Simpson JA. Am J Physiol Heart Circ Physiol. 2015:ajpheart.00773.2015. PMID: 26702144
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Characterizing the metabolic capacity of the anoxic hagfish heart.
Gillis TE, Regan MD, Cox GK, Harter TS, Brauner CJ, Richards JG, Farrell AP. J Exp Biol. 2015;218(Pt 23):3754-61. PMID: 26486366
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Exercise-mediated IL-6 signaling occurs independent of inflammation and is amplified by training in mouse adipose tissue.
Castellani L, Perry CG, Macpherson RE, Root-McCaig J, Huber JS, Arkell AM, Simpson JA, Wright DC. J Appl Physiol. 2015;119(11):1347-54. PMID: 26472868
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Respiratory muscle weakness in the Zucker diabetic fatty rat.
Allwood MA, Foster AJ, Arkell AM, Beaudoin MS, Snook LA, Romanova N, Murrant CL, Holloway GP, Wright DC, Simpson JA. Am J Physiol Regul Integr Comp Physiol. 2015;309(7):R780-7. PMID: 26246509
– Print Publication

High intensity interval and endurance training have opposing effects on markers of heart failure and cardiac remodeling in hypertensive rats.
Holloway TM, Bloemberg D, da Silva ML, Simpson JA, Quadrilatero J, Spriet LL. PLoS One. 2015 Mar;10(3):e0121138. eCollection 2015. PMID: 25803693
– Print Publication

Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice.
Macpherson RE, Huber JS, Frendo-Cumbo S, Simpson JA, Wright DC. Med Sci Sports Exerc. 2015;47(10):2034-42. PMID: 25785928
– Print Publication

Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFa.
Aschar-Sobbi R, Izaddoustdar F, Korogyi AS, Wang Q, Farman GP, Yang F, Yang W, Dorian D, Simpson JA, Tuomi JM, Jones DL, Nanthakumar K, Cox B, Wehrens XH, Dorian P, Backx PH. Nat Commun. 2015;6:6018. PMID: 25598495
– Print Publication

Lennie: a smartphone application with novel implications for the management of animal colonies.
Allwood MA, Griffith D, Allen C, Reed J, Mahmoud QH, Brunt KR, Simpson JA. Lab Anim. 2015;49(3):258-62. PMID: 25653169
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Muscle sympathetic activity in resting and exercising humans with and without heart failure.
Notarius CF, Millar PJ, Floras JS. Appl Physiol Nutr Metab. 2015;40(11):1107-15. PMID: 26481289
– Print Publication

Paradoxical muscle sympathetic reflex activation in human heart failure.
Millar PJ, Murai H, Floras JS. Circulation. 2015;131(5):459-68. PMID: 25466974
– Print Publication

Divergent muscle sympathetic responses to dynamic leg exercise in heart failure and age-matched healthy subjects.
Notarius CF, Millar PJ, Murai H, Morris BL, Marzolini S, Oh P, Floras JS. J Physiol. 2015;593(3):715-22. PMID: 25398528
– Print Publication

Association between Resting State Brain Functional Connectivity and Muscle Sympathetic Burst Incidence.
Taylor KS, Kucyi A, Millar PJ, Murai H, Kimmerly DS, Morris BL Rn, Bradley TD, Floras JS. J Neurophysiol. 2015:jn.00675.2015. PMID: 26538607
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The efficacy of blood flow restricted exercise: A systematic review & meta-analysis.
Slysz J, Stultz J, Burr JF. J Sci Med Sport. 2015. pii: S1440-2440(15)00182-6. PMID: 26463594
– Print Publication

Influence of Active Recovery on Cardiovascular Function During Ice Hockey.
Burr JF, Slysz JT, Boulter MS, Warburton DE. Sports Med Open. 2015;1(1):27. PMID: 26339567
– Print Publication

Arterial stiffness results from eccentrically biased downhill running exercise.
Burr JF, Boulter M, Beck K. J Sci Med Sport. 2015;18(2):230-5. PMID: 24709362
– Print Publication

A systematic review of standing and treadmill desks in the workplace.
MacEwen BT, MacDonald DJ, Burr JF. Prev Med. 2015;70:50-8. PMID: 25448843
– Print Publication

Sex differences in cardiac function after prolonged strenuous exercise.
Cote AT, Phillips AA, Foulds HJ, Charlesworth SA, Bredin SS, Burr JF, Koehle MS, Warburton DE. Clin J Sport Med. 2015;25(3):276-83. PMID: 25010150
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2014

Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.
Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, Gamble KL. J Biol Rhythms. 2014 Aug;29(4):257-76. doi: 10.1177/0748730414543141. PMID: 25238855
– Print Publication

Circadian regulation of myocardial sarcomeric Titin-cap (Tcap, telethonin): identification of cardiac clock-controlled genes using open access bioinformatics data.
Podobed PS, Alibhai FJ, Chow CW, Martino TA. PLoS One. 2014 Aug 14;9(8):e104907. PMID: 25121604
– Print Publication

The day/night proteome in the murine heart.
Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze EV, Ratcliffe WF, Mackay A, Simpson J, Wright DC, Kirby GM, Young ME, Martino TA. Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R121-37. PMID: 24789993
– Print Publication

Short-term disruption of diurnal rhythms after murine myocardial infarction adversely affects long-term myocardial structure and function.
Alibhai FJ, Tsimakouridze EV, Chinnappareddy N, Wright DC, Billia F, O’Sullivan ML, Pyle WG, Sole MJ, Martino TA. Circ Res. 2014 May 23;114(11):1713-22. doi: 10.1161/CIRCRESAHA.114.302995. PMID: 24687134
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Cardiac contraction, calcium transients, and myofilament calcium sensitivity fluctuate with the estrous cycle in young adult female mice.
MacDonald JK, Pyle WG, Reitz CJ, Howlett SE. Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H938-53. doi: 10.1152/ajpheart.00730.2013. PMID: 24464757
– Print Publication

Cold acclimation increases cardiac myofilament function and ventricular pressure generation in trout.
Klaiman JM, Pyle WG, Gillis TE. J Exp Biol. 2014 Dec 1;217(Pt 23):4132-40. doi: 10.1242/jeb.109041. PMID: 25278471
– Print Publication

Troponin assays in the assessment of the equine myocardium.
Rossi TM, Pyle WG, Maxie MG, Pearl DL, Physick-Sheard PW. Equine Vet J. 2014 May;46(3):270-5. doi: 10.1111/evj.12209. PMID: 24215569
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Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P.
Bai F, Caster HM, Rubenstein PA, Dawson JF, Kawai M. J Mol Cell Cardiol. 2014 Sep;74:64-75. doi: 10.1016/j.yjmcc.2014.04.014. PMID: 24793351
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Altered interactions between cardiac myosin binding protein-C and a-cardiac actin variants associated with cardiomyopathies.
Chow ML, Shaffer JF, Harris SP, Dawson JF. Arch Biochem Biophys. 2014 May 15;550-551:28-32. doi: 10.1016/j.abb.2014.04.003. PMID: 24736382
– Print Publication

Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Allwood MA, Kinobe RT, Ballantyne L, Romanova N, Melo LG, Ward CA, Brunt KR, Simpson JA. Cardiovasc Pathol. 2014 Jul-Aug;23(4):231-7. doi: 10.1016/j.carpath.2014.03.007. PMID: 24813593
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Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Beaudoin MS, Perry CG, Arkell AM, Chabowski A, Simpson JA, Wright DC, Holloway GP. J Physiol. 2014 Jun 15;592(Pt 12):2519-33. doi: 10.1113/jphysiol.2013.270538. PMID: 24639481
– Print Publication

Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats.
Beaudoin MS, Snook LA, Arkell AM, Stefanson A, Wan Z, Simpson JA, Holloway GP, Wright DC. Obesity (Silver Spring). 2014 Jul;22(7):1632-42. doi: 10.1002/oby.20717. PMID: 24500776
– Print Publication

Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine.
Murrant CL, Dodd JD, Foster AJ, Inch KA, Muckle FR, Ruiz DA, Simpson JA, Scholl JH. J Physiol. 2014 Mar 15;592(Pt 6):1267-81. doi: 10.1113/jphysiol.2013.264259. PMID: 24469074
– Print Publication

Cold acclimation alters the connective tissue content of the zebrafish (Danio rerio) heart.
Johnson AC, Turko AJ, Klaiman JM, Johnston EF, Gillis TE. J Exp Biol. 2014 Jun 1;217(Pt 11):1868-75. doi: 10.1242/jeb.101196. PMID: 24577447
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Self-assembly enhances the strength of fibers made from vimentin intermediate filament proteins.
Pinto N, Yang FC, Negishi A, Rheinstadter MC, Gillis TE, Fudge DS. Biomacromolecules. 2014 Feb 10;15(2):574-81. doi: 10.1021/bm401600a. PMID: 24359121
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Exercise as medicine: role in the management of primary hypertension.
Millar PJ, Goodman JM. Appl Physiol Nutr Metab. 2014 Jul;39(7):856-8. doi: 10.1139/apnm-2014-0006. PMID: 24773307
– Print Publication

Isometric exercise training for blood pressure management: a systematic review and meta-analysis.
Carlson DJ, Dieberg G, Hess NC, Millar PJ, Smart NA. Mayo Clin Proc. 2014 Mar;89(3):327-34. doi: 10.1016/j.mayocp.2013.10.030. PMID: 24582191
– Print Publication

Statins and the autonomic nervous system.
Millar PJ, Floras JS. Clin Sci (Lond). 2014 Mar;126(6):401-15. doi: 10.1042/CS20130332. PMID: 24274967
– Print Publication

Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions.
Millar PJ, McGowan CL, Cornelissen VA, Araujo CG, Swaine IL. Sports Med. 2014 Mar;44(3):345-56. doi: 10.1007/s40279-013-0118-x. PMID: 24174307
– Print Publication

Inverse relationship between muscle sympathetic activity during exercise and peak oxygen uptake in subjects with and without heart failure.
Notarius CF, Millar PJ, Murai H, Morris BL, Floras JS. J Am Coll Cardiol. 2014 Feb 18;63(6):605-6. doi: 10.1016/j.jacc.2013.08.693. PMID: 23994407
– Print Publication

Characterisation of baroreflex sensitivity of recreational ultra-endurance athletes.
Foulds HJ, Cote AT, Phillips AA, Charlesworth SA, Bredin SS, Burr JF, Drury CT, Ngai S, Fougere RJ, Ivey AC, Warburton DE. Eur J Sport Sci. 2014;14(7):686-94. doi: 10.1080/17461391.2014.884169. PMID: 24601942
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Temporal response of arterial stiffness to ultra-marathon.
Burr JF, Phillips AA, Drury TC, Ivey AC, Warburton DE. Int J Sports Med. 2014 Jul;35(8):658-63. doi: 10.1055/s-0033-1358478. PMID: 24408767
– Print Publication

Long-term ultra-marathon running and arterial compliance.
Burr JF, Drury CT, Phillips AA, Ivey A, Ku J, Warburton DE. J Sci Med Sport. 2014 May;17(3):322-5. doi: 10.1016/j.jsams.2013.04.018. PMID: 23707138
– Print Publication

Breed predisposition and heritability of atrial fibrillation in the Standardbred horse: a retrospective case-control study.
Physick-Sheard P, Kraus M, Basrur P, McGurrin K, Kenney D, Schenkel F. J Vet Cardiol. 2014 Sep;16(3):173-84. doi: 10.1016/j.jvc.2014.03.006. PMID: 25087649
– Print Publication

2013

The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart.
Fares E, Pyle WG, Ray G, Rose RA, Denovan-Wright EM, Chen RP, Howlett SE. PLoS One. 2013 Sep 18;8(9):e74719. doi: 10.1371/journal.pone.0074719. eCollection 2013. PMID: 24058623
– Print Publication

Low molecular weight fibroblast growth factor-2 signals via protein kinase C and myofibrillar proteins to protect against postischemic cardiac dysfunction.
Manning JR, Perkins SO, Sinclair EA, Gao X, Zhang Y, Newman G, Pyle WG, Schultz Jel J. Am J Physiol Heart Circ Physiol. 2013 May 15;304(10):H1382-96. doi: 10.1152/ajpheart.00613.2012. PMID: 23479264
– Print Publication

Identifying a role of the actin capping protein CapZ in B-adrenergic receptor signalling.
Gaikis L, Stewart D, Johnson R, Pyle WG. Acta Physiol (Oxf). 2013 Jan;207(1):173-82. doi: 10.1111/j.1748-1716.2012.02470.x. PMID: 22882973
– Print Publication

Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions.
Arora PD, Wang Y, Bresnick A, Dawson J, Janmey PA, McCulloch CA. Mol Biol Cell. 2013 Mar;24(6):734-47. doi: 10.1091/mbc.E12-10-0754. PMID: 23325791
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Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats.
Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC. Am J Physiol Regul Integr Comp Physiol. 2013 Sep;305(5):R542-51. doi: 10.1152/ajpregu.00200.2013. PMID: 23824959
– Print Publication

Chronic hypoxia exposure of trout embryos alters swimming performance and cardiac gene expression in larvae.
Johnston EF, Alderman SL, Gillis TE. Physiol Biochem Zool. 2013 Sep-Oct;86(5):567-75. doi: 10.1086/672012. PMID: 23995487
– Print Publication

Nucleus-localized 21.5-kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane-associated 18.5-kDa isoform.
Smith GS, Samborska B, Hawley SP, Klaiman JM, Gillis TE, Jones N, Boggs JM, Harauz G. J Neurosci Res. 2013 Mar;91(3):349-62. doi: 10.1002/jnr.23166. PMID: 23184356
– Print Publication

Alpha males: muscle sympathetic discharge on beat-to-beat forearm vascular conductance.
Millar PJ, O’Donnell E. J Physiol. 2013 Sep 15;591(Pt 18):4375-6. doi: 10.1113/jphysiol.2013.261743. PMID: 24037135
– Print Publication

Microneurographic evidence in healthy middle-aged humans for a sympathoexcitatory reflex activated by atrial pressure.
Millar PJ, Murai H, Morris BL, Floras JS. Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H931-8. doi: 10.1152/ajpheart.00375.2013. PMID: 23851279
– Print Publication

Heart rate recovery and heart rate variability are unchanged in patients with coronary artery disease following 12 weeks of high-intensity interval and moderate-intensity endurance exercise training.
Currie KD, Rosen LM, Millar PJ, McKelvie RS, MacDonald MJ. Appl Physiol Nutr Metab. 2013 Jun;38(6):644-50. doi: 10.1139/apnm-2012-0354. PMID: 23724882
– Print Publication

Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women.
Badrov MB, Bartol CL, DiBartolomeo MA, Millar PJ, McNevin NH, McGowan CL. Eur J Appl Physiol. 2013 Aug;113(8):2091-100. doi: 10.1007/s00421-013-2644-5. PMID: 23588257
– Print Publication

Reduced heart rate variability and baroreflex sensitivity in normotensive children with repaired coarctation of the aorta.
Millar PJ, Proudfoot NA, Dillenburg RF, Macdonald MJ. Int J Cardiol. 2013 Sep 20;168(1):587-8. doi: 10.1016/j.ijcard.2013.01.248. PMID: 23453876
– Print Publication

Cardiovascular stress reactivity tasks successfully predict the hypotensive response of isometric handgrip training in hypertensives.
Badrov MB, Horton S, Millar PJ, McGowan CL. Psychophysiology. 2013 Apr;50(4):407-14. doi: 10.1111/psyp.12031. PMID: 23418955
– Print Publication

Simvastatin reduces sympathetic outflow and augments endothelium-independent dilation in non-hyperlipidaemic primary hypertension.
McGowan CL, Murai H, Millar PJ, Notarius CF, Morris BL, Floras JS. Heart. 2013 Feb;99(4):240-6. doi: 10.1136/heartjnl-2012-302980. PMID: 23257173
– Print Publication

Physical activity series: cardiovascular risks of physical activity in apparently healthy individuals: risk evaluation for exercise clearance and prescription.
Goodman J, Thomas S, Burr JF. Can Fam Physician. 2013 Jan;59(1):46-9, e6-e10. PMID: 23341659
– Print Publication

Effects of injectable anesthetic combinations on left ventricular function and cardiac morphology in Sprague-Dawley rats.
Sabatini CF, O’Sullivan ML, Valcour JE, Sears W, Johnson RJ. J Am Assoc Lab Anim Sci. 2013 Jan;52(1):34-43. PMID: 23562031
– Print Publication